Packers vs Cardinals Prediction, Odds & Best Prop Bets – NFL, Week 7

BetMGM Betting Oct 15, 2025, 6:48 PM

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A detail view of an Arizona Cardinals helmet with a 9/11 decal before an NFL football game against the Buffalo Bills in Orchard Park, N.Y., Sunday, Sept. 8, 2024. (AP Photo/Adrian Kraus)

(AP Photo/Adrian Kraus)

The Packers are -6.5 point favorites vs the Cardinals
Total (Over/Under): 44.5 points
Watch this game on FOX

The Green Bay Packers (3-1-1) visit State Farm Stadium to take on the Arizona Cardinals (2-4-0) on Oct. 19. Kickoff is scheduled for 4:25pm EDT in Glendale, AZ.

The Packers are betting favorites in this matchup, with the spread sitting at -6.5 (-110).

The Packers vs. Cardinals Over/Under is 44.5 total points for the game.

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Packers vs. Cardinals Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Packers	-6.5 -110	44.5 -110	-325
Cardinals	+6.5 -110	44.5 -110	260

Packers vs. Cardinals Prediction

The winning team model predicts the Packers will win this game with 72.6% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Packers vs Cardinals Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 52.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Packers players this game, looking at profitable historical betting trends:

Best Packers Player Prop Bets Today

Jordan Love has hit the Pass Attempts Under in 13 of his last 16 games (+9.60 Units / 53% ROI)
Dontayvion Wicks has hit the Receiving Yards Under in 7 of his last 8 away games (+5.85 Units / 65% ROI)
Tucker Kraft has hit the Receptions Under in 11 of his last 16 games (+4.50 Units / 21% ROI)
Jordan Love has hit the Passing Yards Under in 11 of his last 17 games (+4.30 Units / 23% ROI)
Jordan Love has hit the TD Passes Under in 6 of his last 8 away games (+4.20 Units / 41% ROI)

And here are some top NFL player prop bets for Cardinals players for this matchup, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today

Chad Ryland has hit the Field Goals Over in 12 of his last 17 games (+6.85 Units / 36% ROI)
Michael Wilson has hit the Receiving Yards Under in 7 of his last 8 games at home (+5.90 Units / 65% ROI)
Michael Wilson has hit the Receptions Under in 6 of his last 8 games at home (+4.10 Units / 43% ROI)
Michael Wilson has hit the Longest Reception Under in 5 of his last 6 games (+3.85 Units / 56% ROI)
Marvin Harrison Jr. has hit the Receptions Under in 6 of his last 9 games at home (+2.65 Units / 22% ROI)

Receiving Props: Total Receiving Yards for Cardinals vs Packers

Player Name	Over	Under
Tucker Kraft (GB)	45.5 -110	45.5 -118
Trey Mcbride (ARI)	61.5 -115	61.5 -115

Rushing Props: Total Rushing Yards for Cardinals vs Packers

Player Name	Over	Under
Josh Jacobs (GB)	72.5 -115	72.5 -115

Packers Best Bets:

The Green Bay Packers have hit the 1H Team Total Under in 8 of their last 9 away games (+7.15 Units / 75% ROI)
The Green Bay Packers have hit the 4Q Game Total Over in 11 of their last 17 games (+4.55 Units / 24% ROI)
The Green Bay Packers have hit the 1Q Moneyline in 11 of their last 18 games (+4.30 Units / 13% ROI)
The Green Bay Packers have hit the Team Total Over in 6 of their last 9 away games (+2.70 Units / 24% ROI)
The Green Bay Packers have covered the 4Q Spread in 10 of their last 17 games (+2.40 Units / 12% ROI)

Cardinals Best Bets:

The Arizona Cardinals have hit the 3Q Moneyline in 11 of their last 17 games (+8.20 Units / 35% ROI)
The Arizona Cardinals have covered the 3Q Spread in 12 of their last 17 games (+6.55 Units / 31% ROI)
The Arizona Cardinals have covered the 2H Spread in 11 of their last 16 games (+5.93 Units / 32% ROI)
The Arizona Cardinals have hit the 1H Moneyline in 8 of their last 11 games at home (+5.60 Units / 31% ROI)
The Arizona Cardinals have covered the 1H Spread in 8 of their last 11 games at home (+5.40 Units / 41% ROI)

Packers Against the Spread (ATS) Record

Against the spread this NFL season, the Packers are 2-3 (-1.3 Units / -23.64% ROI).

Packers are 3-1 when betting on the Moneyline for -1.2 Units / -5.87% ROI
Packers are 2-3 when betting the Over for -1.3 Units / -23.64% ROI
Packers are 3-2 when betting the Under for +0.8 Units / ROI

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals are 3-3 (-0.3 Units / -4.55% ROI).

Cardinals are 2-4 when betting on the Moneyline for -5.2 Units / -39.54% ROI
Cardinals are 3-3 when betting the Over for -0.3 Units / -4.55% ROI
Cardinals are 3-3 when betting the Under for -0.3 Units / -4.55% ROI

Green Bay Packers: Keys to the Game vs. the Arizona Cardinals

The Packers defense has allowed 6 receptions for 20+ yards this season — fewest in NFL.

The Packers defense has allowed just 8.1 yards per completion (1,105 yards/136 completions) this season — best in NFL; League Avg: 10.6.

The Packers defense has allowed a passer rating of just 42.7 on 3rd and long (99 Pass Attempts) since the 2024 season — best in NFL; League Avg: 82.1.

The Packers defense have allowed just 2.2 yards per play on first drive of the game this season — best in NFL; League Avg: 5.8.

Arizona Cardinals: Keys to the Game vs. the Green Bay Packers

The Cardinals have targeted TEs 33% of the time (68 Pass Attempts/206 plays) this season — highest in NFL; League Avg: 22%.

The Cardinals went three and out 7 times in the 2nd quarter in the last 4 weeks of the regular season — most in NFL.

The Cardinals have converted first downs on 56 of 78 plays (72%) on 3rd and short since the 2024 season — best in NFL; League Avg: 60%.

The Cardinals had a third down conversion rate of 64% in Week 6 — 2nd-best in NFL; League Avg: 38%.

Additional Matchup Notes for Green Bay Packers vs. Arizona Cardinals