Rams vs Cardinals Prediction, Odds & Best Prop Bets – NFL, Week 2

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Arizona Cardinals quarterback Kyler Murray throws a pass against the Philadelphia Eagles during the second half of an NFL football game, Sunday, Dec. 31, 2023, in Philadelphia. (AP Photo/Derik Hamilton)
(AP Photo/Derik Hamilton)
BetMGM Betting @BETMGM Sep 12, 2024, 11:29 AM
  • The Cardinals are -1.5 point favorites vs the Rams
  • Total (Over/Under): 49.5 points
  • Watch this game on FOX

The Los Angeles Rams (0-1-0) visit State Farm Stadium to take on the Arizona Cardinals (0-1-0) on Sep. 15. Kickoff is scheduled for 4:05pm EDT in Glendale, AZ.

The Cardinals are betting favorites in this matchup, with the spread sitting at -1.5 (-110).

The Rams vs. Cardinals Over/Under is 49.5 total points for the game.

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Rams vs. Cardinals Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Rams+1.5 -11049.5 -110+105
Cardinals -1.5 -11049.5 -110-125

Rams vs. Cardinals Prediction

The winning team model predicts the Rams will win this game with 51.5% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Rams vs Cardinals Spread Prediction

Based on recent against-the-spread trends, the model predicts the Rams will cover the spread with 51.5% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Rams players this playoff game, looking at profitable historical betting trends:

Best Rams Player Prop Bets Today

  • Colby Parkinson has hit the Receiving Yards Over in 9 of his last 11 games (+6.50 Units / 50% ROI)
  • Colby Parkinson has hit the Receptions Over in 6 of his last 7 games (+6.05 Units / 69% ROI)
  • Jimmy Garoppolo has hit the Interceptions Over in his last 6 games (+6.00 Units / 69% ROI)
  • Kyren Williams has hit the Carries Over in 9 of his last 12 games (+6.00 Units / 46% ROI)
  • Kyren Williams has hit the Rushing Yards Over in 9 of his last 12 games (+5.65 Units / 41% ROI)

And here are some top NFL player prop bets for Cardinals players for this matchup, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today

  • James Conner has hit the Longest Reception Under in 7 of his last 8 games (+5.75 Units / 58% ROI)
  • Desmond Ridder has hit the Rushing Yards Over in his last 5 games at home (+5.00 Units / 86% ROI)
  • James Conner has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
  • Chris Moore has hit the Receiving Yards Over in 6 of his last 7 games (+4.85 Units / 58% ROI)
  • James Conner has hit the Receiving Yards Under in 10 of his last 14 games (+4.85 Units / 26% ROI)
  • The Los Angeles Rams have covered the 1Q Spread in 14 of their last 21 games (+7.00 Units / 28% ROI)
  • The Los Angeles Rams have hit the Team Total Over in 7 of their last 8 games (+5.90 Units / 58% ROI)
  • The Los Angeles Rams have hit the Moneyline in 12 of their last 21 games (+5.80 Units / 19% ROI)
  • The Los Angeles Rams have covered the Spread in 12 of their last 21 games (+4.30 Units / 19% ROI)
  • The Los Angeles Rams have hit the 3Q Moneyline in 7 of their last 13 games (+4.25 Units / 24% ROI)
  • The Arizona Cardinals have hit the 2Q Game Total Over in 13 of their last 18 games (+7.85 Units / 38% ROI)
  • The Arizona Cardinals have hit the 2H Moneyline in 6 of their last 8 games (+7.10 Units / 89% ROI)
  • The Arizona Cardinals have hit the Game Total Over in 7 of their last 9 games at home (+4.80 Units / 48% ROI)
  • The Arizona Cardinals have scored last in 5 of their last 7 games at home (+4.35 Units / 60% ROI)
  • The Arizona Cardinals have hit the Team Total Over in 6 of their last 8 games at home (+3.95 Units / 40% ROI)

Rams Against the Spread (ATS) Record

Against the spread this NFL preseason, the Rams went 0-1 (-1.1 Units / -100% ROI).

  • Rams are 0-1 when betting on the Moneyline for -1 Units / -100% ROI
  • Rams are 0-1 when betting the Over for -1.15 Units / -100% ROI
  • Rams are 1-0 when betting the Under for +1 Units / ROI

Cardinals Against the Spread (ATS) Record

Against the spread this NFL preseason, the Cardinals went 1-0 (+1 Units / 90.91% ROI).

  • Cardinals are 0-1 when betting on the Moneyline for -1 Units / -100% ROI
  • Cardinals are 1-0 when betting the Over for +1 Units / 90.91% ROI
  • Cardinals are 0-1 when betting the Under for -1.1 Units / -100% ROI

Los Angeles Rams: Keys to the Game vs. the Arizona Cardinals

The Rams were 1-4 (.200) vs top 10 offenses last season — T-7th-worst in NFL; League Avg: .359.

The Rams were 3-1 (.750) when forcing at least one fumble last season — 8th-best in NFL; League Avg: .618.

The Rams were 3-2 (.600) when sacking the QB 3 or more times last season — T-10th-worst in NFL; League Avg: .650.

The Rams were 5-2 (.714) at home last season — 7th-best in NFL; League Avg: .558.

Arizona Cardinals: Keys to the Game vs. the Los Angeles Rams

The Cardinals were winless (0-3) when forcing 2 or more turnovers last season — worst in NFL; League Avg: .707.

The Cardinals were winless (0-10) when scoring less than 22 points last season — T-worst in NFL; League Avg: .254.

The Cardinals are winless (0-13) when losing at least one fumble since the 2022 season — worst in NFL; League Avg: .384.

The Cardinals were 1-6 (.143) when sacking the QB 3 or more times last season — 2nd-worst in NFL; League Avg: .650.

Additional Matchup Notes for Los Angeles Rams vs. Arizona Cardinals

The Cardinals ran successful plays on 46.6% of rush attempts with motion last season — 4th-best in NFL. The Rams allowed successful plays on 46.9% of rush attempts against motion last season — 3rd-worst in NFL.

The Cardinals ran successful plays on just 40.6% of pass attempts against a stacked front last season — 5th-worst in NFL. The Rams allowed successful plays on just 30.8% of pass attempts with a stacked front last season — 4th-best in NFL.

The Cardinals ran successful plays on just 29.6% of pass attempts against a heavy rush last season — worst in NFL. The Rams allowed successful plays on just 26.7% of pass attempts with a heavy rush last season — 3rd-best in NFL.

The Rams ran successful plays on 49.7% of pass attempts against a light front last season — 5th-best in NFL. The Cardinals allowed successful plays on 46.6% of pass attempts with a light front last season — 5th-worst in NFL.

The Rams were successful on 46.0% of plays they have run against a light front last season — 4th-best in NFL. The Cardinals allowed their opponents to be successful on 44.8% of plays with a light front last season — 3rd-worst in NFL.

The Rams ran successful plays on just 33.3% of pass attempts against a heavy rush last season — 3rd-worst in NFL. The Cardinals allowed successful plays on just 18.8% of pass attempts with a heavy rush last season — best in NFL.

Los Angeles Rams Offense: Important Stats

The Rams started 10 drives inside their own 10 yard line last season — 2nd-fewest in NFL.

The Rams went three and out on 6% of their drives in the 1st quarter last season — best in NFL; League Avg: 22%.

The Rams have targeted RBs 11% of the time (124 Pass Attempts/1,108 plays) since the 2022 season — lowest in NFL; League Avg: 18%.

The Rams averaged -0.51 epa per play against a light rush last season — 3rd-worst in NFL; League Avg: -0.04.

Arizona Cardinals Offense: Important Stats

The Cardinals had 23 rushes of 20+ yards last season — most in NFL.

The Cardinals went for two on 36% of PATs last season — highest in NFL; League Avg: 10%.

The Cardinals had 8 rushes of 20+ yards in the last 4 weeks of the regular season — most in NFL.

The Cardinals ran successful plays on 75% of rush attempts against a base rush last season — best in NFL; League Avg: 57%.

Los Angeles Rams Defense: Important Stats

The Rams defense allowed an average of 1.4 yards after contact per carry (388 carries) last season — T-best in NFL; League Avg: 1.8.

The Rams defense allowed successful plays on 59% of pass attempts in the 1st quarter last season — worst in NFL; League Avg: 47%.

Only 12% of the plays ran against the Rams were in the red zone last season — 2nd-best in NFL; League Avg: 14%.

The Rams defense allowed successful plays on 71% of rush attempts in Week 1 — worst in NFL; League Avg: 46%.

Arizona Cardinals Defense: Important Stats

19% of the plays ran against the Cardinals were in the red zone last season — worst in NFL; League Avg: 14%.

18% of the plays run against the Cardinals have been in the red zone since the 2022 season — worst in NFL; League Avg: 14%.

50% of the plays run against the Cardinals have been in their own territory since the 2022 season — worst in NFL; League Avg: 44%.

The Cardinals defense allowed scores on 44% of opponent drives last season — 2nd-worst in NFL; League Avg: 35%.

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About the Author

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.