Who is Most Likely To Be Second Overall Pick in NFL Draft?

Ohio State linebacker Arvell Reese drops back to defend against Miami during the first half of the Cotton Bowl College Football Playoff quarterfinal game Wednesday, Dec. 31, 2025, in Arlington, Texas.
(AP Photo/Gareth Patterson)
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Arvell Reese, a linebacker from Ohio State, is most likely to be drafted second overall by the Jets, as he has the best odds of -150.

*as of April 17.

Second Overall Pick Odds NFL Draft

PlayerOdds to be Second Overall Pick
Arvell Reese-150
David Bailey+110
Sonny Styles+5000
Jeremiyah Love+10000
Rueben Bain Jr.+15000
Ty Simpson+15000

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.