Brentford vs. Southampton Prediction, Odds & Match Preview

Brentford's Bryan Mbeumo runs into position during the English Premier League soccer match between Brentford and Crystal Palace, at the Gtech Community Stadium in London, Sunday, Aug. 18, 2024.
(AP Photo/Dave Shopland)
  • Brentford is predicted to be a -0.5-goal favorite against Southampton.
  • Brentford has won three straight meetings against Southampton.
  • I predict the likeliest outcome is a Brentford victory.

Brentford will look to capture their second home win of the season on Saturday as they welcome Southampton to London.ย 

Both teams enter this match off Matchday 2 defeats. Southampton fell 1-0 as home favorites to Nottingham Forest, while Brentford lost 2-0 at Liverpool.ย 

The good news for Brentford? Theyโ€™ve historically dominated this series, winning three straight meetings.ย 

Hereโ€™s a look at the Premier League odds and my prediction for Saturdayโ€™s fixture.ย 

Brentford vs. Southampton Odds, Premier League

  • Brentford Moneyline: -135
  • Southampton Moneyline: +340
  • Draw Moneyline: +290
  • Over/Under: 2.5 Goals (-155/+110)
  • Both Teams to Score: Yes (-155), No (+110)

Brentford vs. Southampton Prediction: Game Spread

If forced to make a prediction, I would back the Brentford moneyline (-135). However, itโ€™s strictly a lean for me as this feels like a trap.ย 

I can make a case for both sides but with caveats attached to each that lead me to other bets on the board.ย 

The case for Brentford is stronger.ย 

The Bees have historically dominated Southampton. Over the last three meetings, Thomas Frankโ€™s team owns a +8 goal differential and a +6.86 expected goal differential.ย 

Thereโ€™s also a historically profitable system supporting a bet on the hosts.ย 

Since 2012, favorites priced between -199 and +106 are 68.5% SU when both teams lost their last game, and the favorite posted between a +0 and +4 margin in the last head-to-head.ย 

When those teams failed to score in their last game, they improve to 70% SU, including 73% at home.ย 

The issue? Itโ€™s generally better fading teams that closed as underdogs in their last game. That designation doesnโ€™t fit Southampton.ย 

Visitors Southampton also fit a historically profitable system outlined in my EPL predictions. However, it also comes with a caveat.ย 

The system generally works better with road underdogs. However, those road underdogs produce a higher return on investment against home teams off results.ย 

In fact, the ROI percentage of visiting underdogs against teams off a loss between one and three goals is only 2.2%.ย 

Based on conflicting reports, this match is an easy pass with a slight lean to Brentford.ย 

Brentford Record, Last 5 Matches

  • Aug. 25 at Liverpool: 0-2, L
  • Aug. 17 vs. Crystal Palace: 2-1, W
  • Aug. 9 vs. Wolfsburg: 4-4, D (Friendly)
  • Aug. 3 at Watford: 1-1, D (Friendly)
  • July 25 at Benfica: 1-1, D (Friendly)

Southampton Record, Last 5 Matches

  • Aug. 24 vs. Nottingham Forest: 0-1, L
  • Aug. 17 at Newcastle United: 0-1, L
  • Aug. 10 vs. Getafe: 0-0, D (Friendly)
  • Aug. 7 vs. Lazio: 1-1, D (Friendly)
  • Aug. 3 at Millwall: 1-0, W (Friendly)

Visit the BetMGM online sportsbook for the latest Brentford odds and Southampton odds!

EPL Match Schedule This Weekend

HomeAwayDateTime (ET)Location
TottenhamManchester UnitedNov. 87:30 a.m.Tottenham Hotspur Stadium
EvertonFulhamNov. 810 a.m.Hill Dickinson Stadium
West Ham UnitedBurnleyNov. 810 a.m.London Stadium
SunderlandArsenalNov. 812:30 p.m.Stadium of Light
ChelseaWolvesNov. 83 p.m.Stamford Bridge
Aston VillaBournemouthNov. 99 a.m.Villa Park
BrentfordNewcastle UnitedNov. 99 a.m.GTech Community Stadium
Crystal PalaceBrighton & Hove AlbionNov. 99 a.m.Selhurst Park
Nottingham ForestLeeds UnitedNov. 99 a.m.The City Ground
Manchester CityLiverpoolNov. 911:30 a.m.Etihad Stadium

EPL Standings

TeamRecord (Wins-Draws-Losses)PointsGoal Differential
Arsenal8-1-12515
Manchester City6-1-31912
Bournemouth5-3-2183
Liverpool6-0-4184
Sunderland5-3-2184
Tottenham Hotspur5-2-3179
Chelsea5-2-3177
Manchester United5-2-3171
Crystal Palace4-4-2165
Brighton & Hove Albion4-3-3152
Aston Villa4-3-315-1
Brentford4-1-513-1
Newcastle United3-3-412-1
Everton3-3-412-3
Fulham3-2-511-2
Leeds United3-2-511-8
Burnley3-1-610-7
West Ham United2-1-77-11
Nottingham Forest1-3-66-12
Wolverhampton Wanderers0-2-82-15

EPL ATS Records

TeamATS RecordATS%Home ATS RecordHome ATS%Road ATS RecordRoad ATS%
Arsenal4-3-355.0%2-2-150.0%2-1-260.0%
Aston Villa3-5-240.0%2-2-150.0%1-3-130.0%
Bournemouth6-2-270.0%4-0-190.0%2-2-150.0%
Brentford5-4-155.0%4-0-190.0%1-4-020.0%
Brighton & Hove Albion4-6-040.0%3-2-060.0%1-4-020.0%
Burnley6-2-270.0%4-0-190.0%2-2-150.0%
Chelsea5-5-050.0%2-3-040.0%3-2-060.0%
Crystal Palace6-4-060.0%2-3-040.0%4-1-080.0%
Everton3-4-345.0%2-2-150.0%1-2-240.0%
Fulham5-3-260.0%4-0-190.0%1-3-130.0%
Leeds United4-5-145.0%3-1-170.0%1-4-020.0%
Liverpool4-5-145.0%3-1-180.0%1-4-020.0%
Manchester City6-3-165.0%4-1-080.0%2-2-150.0%
Manchester United4-6-040.0%3-2-060.0%1-4-020.0%
Newcastle United2-6-230.0%1-3-130.0%1-3-130.0%
Nottingham Forest3-7-030.0%2-3-040.0%1-4-020.0%
Sunderland7-2-175.0%4-0-190.0%3-1-170.0%
Tottenham Hotspur6-4-060.0%1-4-020.0%5-0-0100.0%
West Ham United3-6-135.0%1-4-020.0%2-2-150.0%
Wolverhampton Wanderers3-7-030.0%1-4-020.0%2-3-040.0%
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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.