NFL Week 8 Picks: My 49ers vs. Cowboys Prediction (Video)

Nick Hennion Oct 21, 2024, 3:05 PM

Based on NFL betting lines at the BetMGM online sportsbook, my 49ers vs. Cowboys prediction is the Cowboys Spread (+5.5) as my first NFL Week 8 pick.

Dallas is coming off a bye week and faces a 49ers team with injuries to key offensive players and an exploitable defense.

Per PFF, the 49ers rank 26th in rush defensive grades. San Francisco also ranks 25th in rushing EPA per play and 22nd in defensive success rate on the ground.

While Dallas has struggled to run the ball this season, the 49ers are their second-easiest opponent by rushing defensive grades this season.

Plus, Dallas matches a historically profitable betting system that has hit at a 78% rate since the 2003 NFL season. Mike McCarthy is also 5-0 ATS as as an underdog with 13 or more days between games.

For that system and more analysis into this NFL Week 8 pick, click the video above!

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