Wake Forest vs Louisville Prediction, Odds & Best Prop Bets – NCAAF, Week 4

• The Louisville Cardinals are a -12.5 point favorite vs. the Wake Forest Demon Deacons
• Wake Forest vs. Louisville Total (Over/Under): 58.5 points
• TV Channel: ESPN | DIS+

Wake Forest (2-1) visit L&N Federal Credit Union Stadium to take on Louisville (2-1) on Sep. 26 in Louisville, KY. Kickoff is scheduled for 12:00 pm.

The Louisville Cardinals are betting favorites in Week 4, with the spread sitting at -12.5 (-108).

The Wake Forest vs. Louisville Over/Under is 58.5 total points.

Bet now on Louisville Cardinals vs Wake Forest Demon Deacons & all NCAAF games with BetMGM

Wake Forest vs. Louisville Odds, Spread, Over/Under:

Wake Forest vs Louisville Prediction:

The winning team model predicts Louisville will win this game with 74.9% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Wake Forest Demon Deacons and the Louisville Cardinals, key player performances this season and recent team trends.

Wake Forest vs Louisville Spread Prediction:

Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 68.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

Bet now on Louisville Cardinals vs Wake Forest Demon Deacons and all games with BetMGM

Wake Forest Best Bets Today

• Wake Forest has hit the 1H Moneyline in 10 of their last 13 games (+10.20 Units / 22% ROI)
• Wake Forest has hit the Moneyline in 9 of their last 13 games (+7.80 Units / 14% ROI)
• Wake Forest have covered the 1H Spread in 10 of their last 13 games (+6.45 Units / 42% ROI)
• Wake Forest have covered the Spread in 9 of their last 13 games (+4.65 Units / 33% ROI)
• Wake Forest has hit the Game Total Over in 9 of their last 13 games (+4.60 Units / 32% ROI)

Louisville Best Bets Today

• Louisville has hit the 1Q Moneyline in 5 of their last 8 games at home (+5.00 Units / 5% ROI)
• Louisville has hit the 1Q Game Total Over in 8 of their last 13 games (+2.60 Units / 18% ROI)
• Louisville has hit the Game Total Over in 5 of their last 8 games at home (+1.70 Units / 19% ROI)
• Louisville has hit the Team Total Under in 5 of their last 8 games at home (+1.45 Units / 16% ROI)
• Louisville have covered the Spread in 7 of their last 13 games (+0.45 Units / 3% ROI)

Wake Forest Against the Spread (ATS) Record

Wake Forest Demon Deacons is 1-2 against the spread this college football season (-1.15 Units / -35.38% ROI).

• Wake Forest is 2-1 when betting on the Moneyline for +1 Units / 2.67% ROI
• Wake Forest is 2-1 when betting the Over for +0.9 Units / 27.11% ROI
• Wake Forest is 1-2 when betting the Under for -1.18 Units / -35.98% ROI

Louisville Against the Spread (ATS) Record

Louisville Cardinals is 3-0 against the spread this college football season (+3 Units / 90.91% ROI).

• Louisville is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
• Louisville is 3-0 when betting the Over for +3 Units / 90.91% ROI
• Louisville is 0-3 when betting the Under for -3.3 Units / -100% ROI

Wake Forest: Keys to the Game vs. Louisville

Wake Forest was 3-5 (.375) when having a turnover margin within one of the opposing team last season– T-11th-worst among Power Conference Teams; Average: .578

Wake Forest was 2-7 (.222) when allowing more than 3 explosive runs last season– T-14th-worst among Power Conference Teams; Average: .459

Wake Forest is 6-2 (.750) when having a turnover margin within one of the opposing team this season– T-25th-best in FBS; Average: .531

Wake Forest was 1-6 (.143) when their opponent rushed more than 30 times last season– 7th-worst among Power Conference Teams; Average: .481

Louisville: Keys to the Game vs. Wake Forest

Louisville was 9-3 (.750) when allowing less than 50% of third down conversion opportunities last season– T-31st-best in FBS; Average: .602

Louisville is 9-2 (.818) when converting 55% or more of its red zone chances into touchdowns this season– T-23rd-best in FBS; Average: .636

Louisville is 6-2 (.750) when sacking the QB less than 3 times this season– T-8th-best among Power Conference Teams; Average: .467

Louisville was 8-3 (.727) when rushing at least 4 yards in a play 10 or more times last season– 35th-best in FBS; Average: .575

Matchup Notes for Wake Forest vs. Louisville

Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Wake Forest’s defense allowed 20+ yards on just 6.6% of attempts last season — T-3rd-best among P5 defenses.

Louisville’s WRs gained 2,188 yards on 186 receptions (just 11.8 YPR) last season — T-2nd-worst among ACC WRs. Wake Forest’s defense allowed just 10.0 Yards Per Reception last season — best among ACC defenses.

Louisville gained 2,853 yards on 266 receptions (just 10.7 YPR) last season — 3rd-worst among ACC skill players. Wake Forest’s defense allowed just 10.0 Yards Per Reception last season — T-3rd-best among P5 defenses.

Wake Forest gained 3,090 yards on 232 receptions (13.3 YPR) last season — 2nd-best among ACC skill players. Louisville’s defense allowed just 10.1 Yards Per Reception last season — 2nd-best among ACC defenses.

Wake Forest’s WRs gained 2,377 yards on 152 receptions (15.6 YPR) last season — 2nd-best among ACC WRs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — T-7th-best among FBS defenses.

Wake Forest’s WRs gained 2,377 yards on 152 receptions (15.6 YPR) last season — T-9th-best among FBS WRs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — T-7th-best among FBS defenses.

Wake Forest Offensive Stats & Trends

Wake Forest Skill Players have no touchdowns on 38 receptions in close and late situations this season– T-worst Receptions Per TD among FBS Teams; Average: 11.8

Wake Forest Skill Players have averaged a touchdown every 3.7 receptions (22 Rec/6 TDs) in the Red Zone this season– T-7th-worst Receptions Per TD among FBS Teams; Average: 2.1

Wake Forest gained 3,090 yards on 232 receptions (13.3 YPR) last season — 2nd-best among ACC skill players. Louisville’s defense allowed just 10.1 Yards Per Reception last season — 2nd-best among ACC defenses.

Wake Forest’s WRs gained 2,377 yards on 152 receptions (15.6 YPR) last season — 2nd-best among ACC WRs. Louisville’s defense allowed just 10.1 Yards Per Reception last season — T-7th-best among FBS defenses.

Wake Forest Skill Players averaged a touchdown every 3.7 receptions (22 Rec/6 TDs) in the Red Zone last season– 3rd-worst Receptions Per TD among Power Conference Teams; Average: 2.1

Louisville Offensive Stats & Trends

Louisville RBs have averaged 10.2 yards from scrimmage per touch (214 yards / 21 touches) on 3rd and short this season– 2nd-best among FBS Teams; Average: 4.5

Louisville’s offense threw for 20 or more yards on just 8.0% of 414 attempts last season — 21st-worst among FBS offenses. Wake Forest’s defense allowed 20+ yards on just 6.6% of attempts last season — T-3rd-best among P5 defenses.

Louisville’s WRs gained 2,188 yards on 186 receptions (just 11.8 YPR) last season — T-2nd-worst among ACC WRs. Wake Forest’s defense allowed just 10.0 Yards Per Reception last season — best among ACC defenses.

Louisville RBs have averaged 7.5 Yards per Carry (702 yards/93 carries) in the 4th quarter this season– T-2nd-best among FBS Teams; Average: 5.1

Louisville RBs have averaged 6.8 Yards per Carry (2,053 yards/300 carries) this season– best among FBS Teams; Average: 5.1

Wake Forest Defensive Stats & Trends

Wake Forest has intercepted 4 of 457 attempts (114.2 pass attempts per int.) this season– 6th-worst in FBS; Average: 38.5

Wake Forest opponents averaged 26.7 completions per game (320 / 12) last season– 2nd-worst in FBS; Average: 18.5

Wake Forest allowed opponents to catch 320 of 445 passes (72% Reception Pct) last season– worst among Power Conference Teams; Average: 62%

Wake Forest opponents averaged 26.7 completions per game (320 / 12) last season– worst among Power Conference Teams; Average: 18.8

Wake Forest allowed opponents to catch 320 of 445 passes (72% Reception Pct) last season– worst in FBS; Average: 62%

Louisville Defensive Stats & Trends

Louisville has tackled opponents for a loss on just 4 of 61 rushing attempts (7% TFL%) in the Red Zone this season– 4th-worst among Power Conference Teams; Average: 15%.

Louisville has tackled opponents for a loss on just 4 of 61 rushing attempts (7% TFL%) in the Red Zone this season– 8th-worst in FBS; Average: 14%.

Louisville has tackled opponents for a loss on just 1 of 26 rushing attempts (4% TFL%) on 3rd and short this season– T-20th-worst in FBS; Average: 11%.

Louisville has allowed passes of 40+ yards on just 2 of 409 attempts (1%) this season– best among Power Conference Teams; Average: 2%

Louisville has allowed just 10.1 yards per completion (2,454 yards/242 completions) this season– T-5th-best among Power Conference Teams; Average: 11.2

Bet now on Louisville Cardinals vs Wake Forest Demon Deacons and all games with BetMGM

More College Football Betting at BetMGM

College football betting is available at the online sportsbook throughout the season.

Whether you’re a first-time bettor checking out the best sportsbook promos, a casual fan betting on Indiana football national championship odds, Michigan football odds, or Ohio State odds this week, or a longtime diehard breaking down trends for live betting, there are entertainment options for everyone.

Visit the sportsbook today to place a college football bet online!