White Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Aug 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Aug 21, 2022, 9:14 AM
  • The White Sox (62-59) are -135 favorites vs the Guardians (64-56)
  • White Sox starting pitcher: Dylan Cease (12-5), 2.08 ERA
  • Guardians starting pitcher: Aaron Civale (2-5), 5.62 ERA
  • Watch the game on Peacock

The Chicago White Sox (-135) visit Progressive Field to take on the Cleveland Guardians (+110) on Sunday, August 21, 2022. First pitch is scheduled for 12:05pm EDT in Cleveland.

The White Sox are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).

The White Sox vs Guardians Over/Under is 7.5 total runs for the game.

So far this season, the White Sox are 61-58 against the spread (ATS), while the Guardians are 64-55 ATS.

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox-1.5 +125O 7.5 -105-135
Guardians +1.5 -155U 7.5 -115+110

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Sunday‘s matchup with 53.3% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the White Sox and Guardians and up-to-date player injuries.


Looking for a risk-free bet up to $1,000? Bet now on Guardians vs White Sox and all MLB games with BetMGM


Best White Sox Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

  • Jose Abreu has hit the Singles Over in 53 of his last 78 games (+25.05 Units / 28% ROI)
  • Jose Abreu has hit the Hits Over in 58 of his last 80 games (+22.35 Units / 13% ROI)
  • Jose Abreu has hit the Total Bases Over in 46 of his last 80 games (+17.55 Units / 21% ROI)
  • Danny Mendick has hit the Runs Over in 10 of his last 11 games (+15.60 Units / 142% ROI)
  • Dylan Cease has hit the Earned Runs Under in 17 of his last 20 games (+13.90 Units / 54% ROI)

Best Guardians Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

  • Steven Kwan has hit the Total Bases Over in 24 of his last 40 games (+14.20 Units / 35% ROI)
  • Jose Ramirez has hit the Runs Under in 22 of his last 30 games at home (+13.10 Units / 35% ROI)
  • Myles Straw has hit the Hits Under in 12 of his last 16 games (+12.85 Units / 80% ROI)
  • Owen Miller has hit the Runs Under in 19 of his last 22 games at home (+12.80 Units / 28% ROI)
  • Josh Naylor has hit the Runs Under in 14 of his last 15 games (+12.30 Units / 49% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Total Under in 66 of their last 121 games (+14.65 Units / 11% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 19 of their last 33 away games (+5.10 Units / 14% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Total Under in 25 of their last 45 games at home (+8.15 Units / 16% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 45 of their last 80 games (+7.30 Units / 8% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this MLB season, the White Sox have gone 54-65 against the Run Line (-12.4 Units / -8.7% ROI).

  • 61-58 when betting on the Moneyline for -10.7 Units / -6.69% ROI
  • 52-58 when betting on the total runs Over for -10.45 Units / -8.02% ROI
  • 58-52 when betting on the total runs Under for +1.3 Units / 0.99% ROI

Guardians Against the Spread (ATS) Record

Against the spread this MLB season, the White Sox have gone 64-55 against the Run Line (+4.55 Units / 3.03% ROI).

  • 64-55 when betting on the Moneyline for +10.05 Units / 6.79% ROI
  • 55-56 when betting on the total runs Over for -6.55 Units / -5% ROI
  • 56-55 when betting on the total runs Under for -4.4 Units / -3.36% ROI

Opponents have a miss rate of 42% (103/243) against Dylan Cease with runners in scoring position this season — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Right-handed hitters have a miss rate of 39% (226/581) against Dylan Cease this season — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Right-handed batters are hitting just .172 (45-for-261) against Dylan Cease this season — 2nd best among qualified SPs in MLB; League Avg: .241 — 98th Percentile.

Opponents have a miss rate of 40% (75/186) against Dylan Cease on the first pitch of at-bats this season — 2nd best among qualified SPs in MLB; League Avg: 26% — 98th Percentile.

Aaron Civale: Guardians Starting Pitcher Stats & Trends

Opponents have a line drive rate of 33% (29/87) against Aaron Civale on inside fastballs since the start of last season — highest in MLB among starting pitchers with at least 139 total IP; League Avg: 22% — 0 Percentile.

The last hit on a Aaron Civale curveball was July 8th. Hitters are 0 for their last 18 in ABs ending on his curveball. — Dustin May has the longest active streak at 29.

Aaron Civale has not allowed a home run in any of the last 20.1 innings he’s appeared — David Phelps has the longest active streak at 61.1.

10 of Aaron Civale’s 40 breaking pitch strikeouts (25%) have been backdoor this season — 8th highest in MLB among starting pitchers with at least 58 total IP; League Avg: 12% — 91st Percentile.

White Sox Keys to the Game vs. the Guardians

The White Sox are just 5-44 (.102) when allowing 5 or more runs this season — tied for 2nd lowest in MLB; League Avg: .201.

The White Sox are 19-4 (.826) when hitting 2 or more home runs this season — 3rd best in MLB; League Avg: .712.

The White Sox are 11-2 (.846) when totaling 5 or more extra base hits this season — 10th best in MLB; League Avg: .796.

The White Sox are just 6-30 (.167) when allowing 10 or more hits this season — tied for 4th lowest in MLB; League Avg: .275.

Guardians Keys to the Game vs. the White Sox

The Guardians are 10-49 (.169) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .087.

The Guardians are 38-5 (.884) when totaling 10 or more hits this season — 2nd best in MLB; League Avg: .725.

The Guardians are 10-9 (.526) when tied entering the 7th inning this season — 10th best in MLB; League Avg: .500.

The Guardians are 32-31 (.508) on the road this season — 10th best in MLB; League Avg: .471.

White Sox hitters have an OPS of just .438 (261 PA’s) in lefty-lefty matchups since the start of last season — lowest in MLB; League Avg: .652.

White Sox hitters have pulled just 41% of balls they’ve put into play against LHP since the start of last season — 2nd lowest in MLB; League Avg: 45%.

White Sox hitters have an OPS of just .394 (64 PA’s) in lefty-lefty matchups this season — 2nd lowest in MLB; League Avg: .644.

White Sox hitters have pulled just 40% of balls they’ve put into play against LHP this season — lowest in MLB; League Avg: 46%.

Guardians hitters have just 593 strikeouts in 3,394 PA’s (17%) against RHP this season — best in MLB; League Avg: 22%.

Guardians hitters have missed on just 21% of swings this season — best in MLB; League Avg: 25%.

Guardians hitters are slugging just .332 against LHP this season — 2nd lowest in MLB; League Avg: .398.

Guardians hitters have an OPS of just .629 (1,143 PA’s) against LHP this season — 2nd lowest in MLB; League Avg: .714.

White Sox pitchers have a strikeout rate of 46% with two-strikes since the start of last season — 4th best in MLB; League Avg: 43%.

White Sox pitchers have a strikeout rate of 26% since the start of last season — tied for 3rd best in MLB; League Avg: 23%.

Opponents have a miss rate of 28% against White Sox pitchers since the start of last season — 3rd best in MLB; League Avg: 26%.

The White Sox pitchers have allowed the 27th hardest ball in play hit (119.1 MPH) this season (; League Avg: 116.7).

Guardians pitchers have walked 23 of 455 batters (5%) over the last 14 days (13 games) — best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .195 against Guardians pitchers with the shift since the start of last season — 2nd best in MLB; League Avg: .223.

Guardians pitchers have walked 66 of 1,067 batters (6%) when facing the leadoff batter in the inning this season — tied for 3rd best in MLB; League Avg: 7%.

Opponents have a groundball batting average of just .195 against Guardians pitchers with the shift since the start of 2020 — 2nd best in MLB; League Avg: .224.

Guardians vs. White Sox Injuries Tonight That May Affect Prop Bets 

  • Cody Morris (Guardians): Shoulder, D60
  • Austin Hedges (Guardians): Ankle, Day-to-Day
  • Anthony Gose (Guardians): Triceps, D60
  • Yasmani Grandal (White Sox): , Day-to-Day
  • Kyle Crick (White Sox): Elbow, D15
  • Jonathan Stiever (White Sox): Lat, D60
  • Timothy Anderson (White Sox): Finger, D10
  • Garrett Crochet (White Sox): Elbow, D60
  • Aaron Bummer (White Sox): Lat, D15
  • Daniel Mendick (White Sox): Knee, D60
  • Leury García (White Sox): Back, D10

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.