White Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Aug 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Aug 21, 2022, 9:14 AM
  • The White Sox (62-59) are -135 favorites vs the Guardians (64-56)
  • White Sox starting pitcher: Dylan Cease (12-5), 2.08 ERA
  • Guardians starting pitcher: Aaron Civale (2-5), 5.62 ERA
  • Watch the game on Peacock

The Chicago White Sox (-135) visit Progressive Field to take on the Cleveland Guardians (+110) on Sunday, August 21, 2022. First pitch is scheduled for 12:05pm EDT in Cleveland.

The White Sox are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).

The White Sox vs Guardians Over/Under is 7.5 total runs for the game.

So far this season, the White Sox are 61-58 against the spread (ATS), while the Guardians are 64-55 ATS.

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox-1.5 +125O 7.5 -105-135
Guardians +1.5 -155U 7.5 -115+110

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Sunday‘s matchup with 53.3% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the White Sox and Guardians and up-to-date player injuries.


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Best White Sox Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

  • Jose Abreu has hit the Singles Over in 53 of his last 78 games (+25.05 Units / 28% ROI)
  • Jose Abreu has hit the Hits Over in 58 of his last 80 games (+22.35 Units / 13% ROI)
  • Jose Abreu has hit the Total Bases Over in 46 of his last 80 games (+17.55 Units / 21% ROI)
  • Danny Mendick has hit the Runs Over in 10 of his last 11 games (+15.60 Units / 142% ROI)
  • Dylan Cease has hit the Earned Runs Under in 17 of his last 20 games (+13.90 Units / 54% ROI)

Best Guardians Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

  • Steven Kwan has hit the Total Bases Over in 24 of his last 40 games (+14.20 Units / 35% ROI)
  • Jose Ramirez has hit the Runs Under in 22 of his last 30 games at home (+13.10 Units / 35% ROI)
  • Myles Straw has hit the Hits Under in 12 of his last 16 games (+12.85 Units / 80% ROI)
  • Owen Miller has hit the Runs Under in 19 of his last 22 games at home (+12.80 Units / 28% ROI)
  • Josh Naylor has hit the Runs Under in 14 of his last 15 games (+12.30 Units / 49% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Total Under in 66 of their last 121 games (+14.65 Units / 11% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 19 of their last 33 away games (+5.10 Units / 14% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Total Under in 25 of their last 45 games at home (+8.15 Units / 16% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 45 of their last 80 games (+7.30 Units / 8% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this MLB season, the White Sox have gone 54-65 against the Run Line (-12.4 Units / -8.7% ROI).

  • 61-58 when betting on the Moneyline for -10.7 Units / -6.69% ROI
  • 52-58 when betting on the total runs Over for -10.45 Units / -8.02% ROI
  • 58-52 when betting on the total runs Under for +1.3 Units / 0.99% ROI

Guardians Against the Spread (ATS) Record

Against the spread this MLB season, the White Sox have gone 64-55 against the Run Line (+4.55 Units / 3.03% ROI).

  • 64-55 when betting on the Moneyline for +10.05 Units / 6.79% ROI
  • 55-56 when betting on the total runs Over for -6.55 Units / -5% ROI
  • 56-55 when betting on the total runs Under for -4.4 Units / -3.36% ROI

Opponents have a miss rate of 42% (103/243) against Dylan Cease with runners in scoring position this season — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Right-handed hitters have a miss rate of 39% (226/581) against Dylan Cease this season — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Right-handed batters are hitting just .172 (45-for-261) against Dylan Cease this season — 2nd best among qualified SPs in MLB; League Avg: .241 — 98th Percentile.

Opponents have a miss rate of 40% (75/186) against Dylan Cease on the first pitch of at-bats this season — 2nd best among qualified SPs in MLB; League Avg: 26% — 98th Percentile.

Aaron Civale: Guardians Starting Pitcher Stats & Trends

Opponents have a line drive rate of 33% (29/87) against Aaron Civale on inside fastballs since the start of last season — highest in MLB among starting pitchers with at least 139 total IP; League Avg: 22% — 0 Percentile.

The last hit on a Aaron Civale curveball was July 8th. Hitters are 0 for their last 18 in ABs ending on his curveball. — Dustin May has the longest active streak at 29.

Aaron Civale has not allowed a home run in any of the last 20.1 innings he’s appeared — David Phelps has the longest active streak at 61.1.

10 of Aaron Civale’s 40 breaking pitch strikeouts (25%) have been backdoor this season — 8th highest in MLB among starting pitchers with at least 58 total IP; League Avg: 12% — 91st Percentile.

White Sox Keys to the Game vs. the Guardians

The White Sox are just 5-44 (.102) when allowing 5 or more runs this season — tied for 2nd lowest in MLB; League Avg: .201.

The White Sox are 19-4 (.826) when hitting 2 or more home runs this season — 3rd best in MLB; League Avg: .712.

The White Sox are 11-2 (.846) when totaling 5 or more extra base hits this season — 10th best in MLB; League Avg: .796.

The White Sox are just 6-30 (.167) when allowing 10 or more hits this season — tied for 4th lowest in MLB; League Avg: .275.

Guardians Keys to the Game vs. the White Sox

The Guardians are 10-49 (.169) when trailing entering the 8th inning this season — 2nd best in MLB; League Avg: .087.

The Guardians are 38-5 (.884) when totaling 10 or more hits this season — 2nd best in MLB; League Avg: .725.

The Guardians are 10-9 (.526) when tied entering the 7th inning this season — 10th best in MLB; League Avg: .500.

The Guardians are 32-31 (.508) on the road this season — 10th best in MLB; League Avg: .471.

White Sox hitters have an OPS of just .438 (261 PA’s) in lefty-lefty matchups since the start of last season — lowest in MLB; League Avg: .652.

White Sox hitters have pulled just 41% of balls they’ve put into play against LHP since the start of last season — 2nd lowest in MLB; League Avg: 45%.

White Sox hitters have an OPS of just .394 (64 PA’s) in lefty-lefty matchups this season — 2nd lowest in MLB; League Avg: .644.

White Sox hitters have pulled just 40% of balls they’ve put into play against LHP this season — lowest in MLB; League Avg: 46%.

Guardians hitters have just 593 strikeouts in 3,394 PA’s (17%) against RHP this season — best in MLB; League Avg: 22%.

Guardians hitters have missed on just 21% of swings this season — best in MLB; League Avg: 25%.

Guardians hitters are slugging just .332 against LHP this season — 2nd lowest in MLB; League Avg: .398.

Guardians hitters have an OPS of just .629 (1,143 PA’s) against LHP this season — 2nd lowest in MLB; League Avg: .714.

White Sox pitchers have a strikeout rate of 46% with two-strikes since the start of last season — 4th best in MLB; League Avg: 43%.

White Sox pitchers have a strikeout rate of 26% since the start of last season — tied for 3rd best in MLB; League Avg: 23%.

Opponents have a miss rate of 28% against White Sox pitchers since the start of last season — 3rd best in MLB; League Avg: 26%.

The White Sox pitchers have allowed the 27th hardest ball in play hit (119.1 MPH) this season (; League Avg: 116.7).

Guardians pitchers have walked 23 of 455 batters (5%) over the last 14 days (13 games) — best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .195 against Guardians pitchers with the shift since the start of last season — 2nd best in MLB; League Avg: .223.

Guardians pitchers have walked 66 of 1,067 batters (6%) when facing the leadoff batter in the inning this season — tied for 3rd best in MLB; League Avg: 7%.

Opponents have a groundball batting average of just .195 against Guardians pitchers with the shift since the start of 2020 — 2nd best in MLB; League Avg: .224.

Guardians vs. White Sox Injuries Tonight That May Affect Prop Bets 

  • Cody Morris (Guardians): Shoulder, D60
  • Austin Hedges (Guardians): Ankle, Day-to-Day
  • Anthony Gose (Guardians): Triceps, D60
  • Yasmani Grandal (White Sox): , Day-to-Day
  • Kyle Crick (White Sox): Elbow, D15
  • Jonathan Stiever (White Sox): Lat, D60
  • Timothy Anderson (White Sox): Finger, D10
  • Garrett Crochet (White Sox): Elbow, D60
  • Aaron Bummer (White Sox): Lat, D15
  • Daniel Mendick (White Sox): Knee, D60
  • Leury García (White Sox): Back, D10

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.