West Virginia vs Iowa State Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 5

An Iowa State helmet is seen on the Bech during the first half of an NCAA college football game against Baylor, Saturday, Sept. 24, 2022, in Ames, Iowa. (AP Photo/Charlie Neibergall)
(AP Photo/Charlie Neibergall)
Sportsbook Promos This Week
  • The Iowa State Cyclones are a -2 point favorite vs. the West Virginia Mountaineers
  • West Virginia vs. Iowa State Total (Over/Under): 52.5 points
  • TV Channel: TNT | tru

West Virginia (3-1) visit Jack Trice Stadium to take on Iowa State (2-2) on Oct. 3 in Ames, IA. Kickoff is scheduled for 12:00 pm.

The Iowa State Cyclones are betting favorites in Week 5, with the spread sitting at -2 (-145).

The West Virginia vs. Iowa State Over/Under is 52.5 total points.

Bet now on Iowa State Cyclones vs West Virginia Mountaineers & all NCAAF games with BetMGM

West Virginia vs. Iowa State Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
West Virginia+2 +11052.5 -110+130
Iowa State -2 -14552.5 -120-155

West Virginia vs Iowa State Prediction:

The winning team model predicts Iowa State will win this game with 58.6% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the West Virginia Mountaineers and the Iowa State Cyclones, key player performances this season and recent team trends.

West Virginia vs Iowa State Spread Prediction:

Based on recent against-the-spread trends, the model predicts Iowa State will cover the spread with 57.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Iowa State Cyclones vs West Virginia Mountaineers and all games with BetMGM


  • West Virginia has hit the Game Total Over in their last 5 away games (+5.00 Units / 91% ROI)
  • West Virginia has hit the Moneyline in 2 of their last 5 away games (+4.65 Units / 93% ROI)
  • West Virginia has hit the 1Q Moneyline in 6 of their last 11 games (+3.00 Units / 1% ROI)
  • West Virginia has hit the 1H Game Total Over in 4 of their last 5 away games (+2.95 Units / 53% ROI)
  • West Virginia have covered the Spread in 4 of their last 5 away games (+2.90 Units / 53% ROI)
  • Iowa State has hit the 1H Game Total Over in 5 of their last 6 games at home (+3.85 Units / 55% ROI)
  • Iowa State has hit the 1Q Moneyline in 6 of their last 11 games (+3.30 Units / 11% ROI)
  • Iowa State has hit the 1H Moneyline in 7 of their last 11 games (+3.30 Units / 3% ROI)
  • Iowa State has hit the Game Total Under in 7 of their last 11 games (+2.62 Units / 22% ROI)
  • Iowa State have covered the 1H Spread in 7 of their last 11 games (+2.43 Units / 19% ROI)

West Virginia Against the Spread (ATS) Record

West Virginia Mountaineers is 2-2 against the spread this college football season (-0.2 Units / -4.55% ROI).

  • West Virginia is 2-1 when betting on the Moneyline for +3.1 Units / 17.97% ROI
  • West Virginia is 4-0 when betting the Over for +4 Units / 90.91% ROI
  • West Virginia is 0-4 when betting the Under for -4.4 Units / -100% ROI

Iowa State Against the Spread (ATS) Record

Iowa State Cyclones is 2-2 against the spread this college football season (-0.22 Units / -4.98% ROI).

  • Iowa State is 2-2 when betting on the Moneyline for +0 Units / 0% ROI
  • Iowa State is 2-2 when betting the Over for -0.2 Units / -4.52% ROI
  • Iowa State is 2-2 when betting the Under for -0.18 Units / -4.11% ROI

West Virginia: Keys to the Game vs. Iowa State

West Virginia is 4-7 (.364) when having a turnover margin within one of the opposing team since the 2024 season– T-6th-worst among Power Conference Teams; Average: .621

West Virginia was 3-7 (.300) when allowing 200 or more passing yards last season– T-29th-worst in FBS; Average: .481

West Virginia is 7-7 (.500) when rushing more than 30 times since the 2024 season– T-10th-worst among Power Conference Teams; Average: .696

West Virginia is 4-8 (.333) when allowing 5 or more explosive passes since the 2024 season– T-12th-worst among Power Conference Teams; Average: .507

Iowa State: Keys to the Game vs. West Virginia

Iowa State was 8-1 (.889) when intercepting at least 1 pass last season– T-12th-best in FBS; Average: .668

Iowa State is 5-4 (.556) when the opposing team rushes more than 30 times since the 2024 season– T-39th-best in FBS; Average: .449

Iowa State was 6-1 (.857) when allowing less than 5 yards per rush last season– 11th-best among Power Conference Teams; Average: .647

Iowa State is 9-3 (.750) when allowing less than 5 yards per rush since the 2024 season– T-29th-best in FBS; Average: .633

Matchup Notes for West Virginia vs. Iowa State

Iowa State gained 2,657 yards on 210 receptions (12.7 YPR) last season — T-33rd-best among FBS skill players. West Virginia’s defense allowed 12.6 Yards Per Reception last season — T-23rd-worst among FBS defenses.

Iowa State gained 2,657 yards on 210 receptions (12.7 YPR) last season — 3rd-best among Big 12 skill players. West Virginia’s defense allowed 12.6 Yards Per Reception last season — 3rd-worst among Big 12 defenses.

Iowa State’s TEs had 76 receptions in 12 games (6.3 per game) last season — best among Big 12 TEs. West Virginia’s defense allowed 21.1 receptions per game last season — 22nd-worst among FBS defenses.

West Virginia’s WRs has 289 receptions in 29 games (just 10.0 per game) since the 2024 season — T-21st-worst among FBS WRs. Iowa State’s defense has allowed just 10.6 receptions per game to WRs since the 2024 season — T-17th-best among FBS defenses.

West Virginia has 456 receptions in 29 games (just 15.7 per game) since the 2024 season — T-18th-worst among FBS skill players. Iowa State’s defense has allowed just 16.6 receptions per game since the 2024 season — T-15th-best among FBS defenses.

West Virginia’s WRs had just 130.1 receiving yards per game last season — 34th-worst among FBS WRs. Iowa State’s defense allowed 175.9 receiving yards per game to WRs last season — 28th-worst among FBS defenses.

West Virginia Offensive Stats & Trends

West Virginia Skill Players have no receptions on 3 targets in the Red Zone this season– worst among Power Conference Teams; Average: 59%

West Virginia WRs have no receptions on 7 targets in the Red Zone since the 2024 season– worst among Power Conference Teams; Average: 55%

West Virginia WRs have no receptions on 7 targets in the Red Zone since the 2024 season– worst among Big 12 Teams; Average: 54%

West Virginia Skill Players have caught just 5 of 18 passes (28% Reception Pct) in the Red Zone since the 2024 season– worst among Big 12 Teams; Average: 58%

West Virginia Skill Players have averaged just 9.8 receptions per game (39/4) this season– worst among Big 12 Teams; Average: 19.4

Iowa State Offensive Stats & Trends

Iowa State Skill Players have averaged just 3.8 yards per reception (19 yards/5 catches) on 3rd and long this season– worst among Power Conference Teams; Average: 14.4

Iowa State WRs have no touchdowns on 1 receptions in the Red Zone this season– 3rd-worst Receptions Per TD among Big 12 Teams; Average: 1.6

Iowa State WRs have averaged just 6.0 yards per reception (6 yards/1 catches) on 3rd and long this season– worst among Big 12 Teams; Average: 16.6

Iowa State Skill Players had no touchdowns on 40 receptions in close and late situations last season– T-worst Receptions Per TD among Power Conference Teams; Average: 12.7

Iowa State threw one TD on 100 pass attempts in the 4th quarter last season– 6th-worst among FBS Offenses; Average: 19.9

West Virginia Defensive Stats & Trends

West Virginia allowed passes of 20+ yards on 10 of 27 attempts (37%) last week– worst in FBS; Average: 10%

West Virginia has allowed 211.8 yards from scrimmage per game to WRs since the 2024 season– worst in the Big 12; Average: 154.6

West Virginia defense allowed 10 completions for 20 or more yards last week– most among Power Conference Teams

West Virginia has allowed 4 TD passes in close and late situations this season– most in the Big 12

West Virginia intercepted 5 of 386 attempts (77.2 pass attempts per int.) last season– worst in the Big 12; Average: 32.7

Iowa State Defensive Stats & Trends

Iowa State has not recorded a sack (46 pass attempts) in the Red Zone since the 2024 season– T-worst among Power Conference Teams; Average: 15.5

Iowa State allowed a Completion Pct of just 41% (21 completions/51 attempts) when opponents had over 10 yards to go in the 2023 season– best in the Big 12; Average: 61%

Iowa State allowed a Completion Pct of just 53% (196 completions/373 attempts) last season– 2nd-best among Power Conference Teams; Average: 61%

Iowa State allowed a Completion Pct of just 35% (12 completions/34 attempts) in close and late situations last season– best among Power Conference Teams; Average: 59%

Iowa State has not recorded a sack (46 pass attempts) in the Red Zone since the 2024 season– T-worst in FBS; Average: 15.7


Bet now on Iowa State Cyclones vs West Virginia Mountaineers and all games with BetMGM


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