UL Monroe vs South Alabama Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 5

South Alabama head coach Major Applewhite reacts during an NCAA football game against Coastal Carolina on Saturday, Sept. 20, 2025, in Mobile, Ala.
(AP Photo/Matthew Hinton)
Odds Boost This Weekend
  • The South Alabama Jaguars are a -14 point favorite vs. the Louisiana-Monroe Warhawks
  • UL Monroe vs. South Alabama Total (Over/Under): 55.5 points
  • TV Channel: ESPN+

UL Monroe (0-4) visit Hancock Whitney Stadium to take on South Alabama (2-2) on Oct. 3 in Mobile, AL. Kickoff is scheduled for 7:00 pm.

The South Alabama Jaguars are betting favorites in Week 5, with the spread sitting at -14 (-108).

The UL Monroe vs. South Alabama Over/Under is 55.5 total points.

Bet now on South Alabama Jaguars vs Louisiana-Monroe Warhawks & all NCAAF games with BetMGM

UL Monroe vs. South Alabama Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
UL Monroe+14 -11055.5 +105+450
South Alabama -14 -10855.5 -135-600

UL Monroe vs South Alabama Prediction:

The winning team model predicts South Alabama will win this game with 73.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Louisiana-Monroe Warhawks and the South Alabama Jaguars, key player performances this season and recent team trends.

UL Monroe vs South Alabama Spread Prediction:

Based on recent against-the-spread trends, the model predicts UL Monroe will cover the spread with 54.2% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on South Alabama Jaguars vs Louisiana-Monroe Warhawks and all games with BetMGM


  • UL Monroe has hit the Team Total Under in 9 of their last 12 games (+5.65 Units / 42% ROI)
  • UL Monroe has hit the 1Q Game Total Over in 8 of their last 12 games (+2.90 Units / 20% ROI)
  • UL Monroe have covered the 1Q Spread in 5 of their last 7 away games (+2.75 Units / 35% ROI)
  • UL Monroe has hit the Game Total Over in 7 of their last 12 games (+1.50 Units / 11% ROI)
  • UL Monroe has hit the 1H Game Total Over in 7 of their last 12 games (+1.20 Units / 9% ROI)
  • South Alabama has hit the Game Total Over in 8 of their last 11 games (+4.70 Units / 39% ROI)
  • South Alabama have covered the 1Q Spread in 4 of their last 5 games at home (+2.85 Units / 47% ROI)
  • South Alabama has hit the 1H Game Total Over in 4 of their last 5 games at home (+2.80 Units / 49% ROI)
  • South Alabama has hit the 1Q Moneyline in 4 of their last 5 games at home (+2.45 Units / 26% ROI)
  • South Alabama has hit the Team Total Over in 7 of their last 11 games (+2.45 Units / 19% ROI)

UL Monroe Against the Spread (ATS) Record

Louisiana-Monroe Warhawks is 1-3 against the spread this college football season (-2.3 Units / -52.27% ROI).

  • UL Monroe is 0-4 when betting on the Moneyline for -7.1 Units / -100% ROI
  • UL Monroe is 3-1 when betting the Over for +1.9 Units / 43.18% ROI
  • UL Monroe is 1-3 when betting the Under for -2.3 Units / -52.27% ROI

South Alabama Against the Spread (ATS) Record

South Alabama Jaguars is 2-2 against the spread this college football season (-0.2 Units / -4.55% ROI).

  • South Alabama is 2-2 when betting on the Moneyline for +0 Units / 0% ROI
  • South Alabama is 3-1 when betting the Over for +1.9 Units / 43.18% ROI
  • South Alabama is 1-3 when betting the Under for -2.3 Units / -52.27% ROI

UL Monroe: Keys to the Game vs. South Alabama

Louisiana-Monroe is winless (0-12) when allowing 100 or more rushing yards since the 2024 season– T-worst among Non-Power Conference Teams; Average: .380

Louisiana-Monroe is winless (0-11) when averaging less than 5 yards per rush since the 2024 season– T-worst among Non-Power Conference Teams; Average: .366

Louisiana-Monroe is winless (0-13) when the opposing team rushes more than 30 times since the 2024 season– T-worst in FBS; Average: .449

Louisiana-Monroe is winless (0-12) when allowing 120 or more rushing yards since the 2024 season– T-worst among Non-Power Conference Teams; Average: .339

South Alabama: Keys to the Game vs. UL Monroe

South Alabama was 2-6 (.250) when allowing 200 or more passing yards last season– T-16th-worst in FBS; Average: .481

South Alabama was 7-2 (.778) when intercepting at least 1 pass last season– T-37th-best in FBS; Average: .668

South Alabama is winless (0-8) when intercepting no passes since the 2024 season– T-worst among Non-Power Conference Teams; Average: .311

South Alabama was 2-6 (.250) when allowing 200 or more passing yards last season– T-13th-worst among Non-Power Conference Teams; Average: .462

Matchup Notes for UL Monroe vs. South Alabama

South Alabama’s RBs has rushed for 4,651 yards on 858 carries (5.4 YPC) since the 2024 season — T-31st-best among FBS RBs. Louisiana-Monroe’s defense have allowed 4.8 YPC since the 2024 season — T-17th-worst among FBS defenses.

South Alabama had just 1.1 receiving touchdowns per game last season — T-24th-worst among FBS skill players. Louisiana-Monroe’s defense allowed 1.8 receiving touchdowns per game last season — T-27th-worst among FBS defenses.

South Alabama’s RBs has rushed for 4,651 yards on 858 carries (5.4 YPC) since the 2024 season — T-31st-best among FBS RBs. Louisiana-Monroe’s defense have allowed 5.5 YPC to RBs since the 2024 season — T-11th-worst among FBS defenses.

Louisiana-Monroe had 171 receptions in 12 games (just 14.2 per game) last season — T-18th-worst among FBS skill players. South Alabama’s defense allowed just 17.2 receptions per game last season — T-33rd-best among FBS defenses.

Louisiana-Monroe’s WRs had 108 receptions in 12 games (just 9.0 per game) last season — T-22nd-worst among FBS WRs. South Alabama’s defense allowed just 17.2 receptions per game last season — T-33rd-best among FBS defenses.

Louisiana-Monroe’s WRs had 108 receptions in 12 games (just 9.0 per game) last season — T-22nd-worst among FBS WRs. South Alabama’s defense allowed just 10.9 receptions per game to WRs last season — T-35th-best among FBS defenses.

UL Monroe Offensive Stats & Trends

Louisiana-Monroe Skill Players averaged 19.4 yards per reception (485 yards/25 catches) in the 4th quarter last season– best among FBS Teams; Average: 12.0

Louisiana-Monroe WRs averaged 22.6 yards per reception (430 yards/19 catches) in the 4th quarter last season– best among FBS Teams; Average: 13.2

Louisiana-Monroe completed passes for 40+ yards on 3 of their 30 total passing attempts (10%) last week– T-5th-best among FBS Offenses; Average: 2%

Louisiana-Monroe gained 40+ yards on 3 of their 23 receptions (13%) last week– 6th-best among FBS Offenses; Average: 4%

Louisiana-Monroe WRs averaged 24.4 yards per reception (220 yards/9 catches) in close and late situations last season– best among FBS Teams; Average: 13.2

South Alabama Offensive Stats & Trends

South Alabama RBs have carried the ball 40 times in close and late situations this season– most among FBS Teams

South Alabama RBs have carried the ball 103 times in close and late situations since the 2024 season– 2nd-most among FBS Teams

South Alabama RBs have carried the ball 24 times on 3rd down this season– 3rd-most among FBS Teams

South Alabama RBs averaged 6.2 Yards per Carry (1,919 yards/308 carries) last season– 9th-best among FBS Teams; Average: 5.1

South Alabama have averaged just 6.9 yards per completion (124 yards/18 completions) in the 4th quarter this season– 6th-worst among FBS Offenses; Average: 11.8

UL Monroe Defensive Stats & Trends

Louisiana-Monroe has allowed 5.0 touchdowns per interception (30 TDs allowed, and 6 INT) since the 2024 season– T-6th-worst in FBS; Average: 1.8

Louisiana-Monroe has allowed 5.0 touchdowns per interception (30 TDs allowed, and 6 INT) since the 2024 season– 4th-worst among Non-Power Conference Teams; Average: 1.9

The Louisiana-Monroe defense has allowed scores on 42% of opponent drives (17/40) in the 1st half this season– worst in FBS; Average: 23%

The Louisiana-Monroe defense has allowed scores on 33% of opponent drives (26/79) this season– 3rd-worst in FBS; Average: 22%

Louisiana-Monroe has intercepted 6 of 480 attempts (80.0 pass attempts per int.) since the 2024 season– 3rd-worst among Non-Power Conference Teams; Average: 38.2

South Alabama Defensive Stats & Trends

South Alabama did not record a sack (52 pass attempts) in the Red Zone last season– T-worst in FBS; Average: 15.0

South Alabama opponents averaged 8.7 Passing Attempts per TD (52 Pass Attempts/6 Passing TDs) in the Red Zone last season– 2nd-best in FBS; Average: 3.9

South Alabama has allowed opponents to rush for 20+ yards on 10 of their 116 carries (9%) this season– 2nd-worst in FBS; Average: 3%

South Alabama opponents averaged 8.7 Passing Attempts per TD (52 Pass Attempts/6 Passing TDs) in the Red Zone last season– best among Non-Power Conference Teams; Average: 3.8

South Alabama allowed 400.0 yards from scrimmage per game to RBs last week– worst in FBS; Average: 141.0


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