Houston March Madness Odds: Championship, Final Four, Sweet 16

Houston head coach Kelvin Sampson reacts during the first half of an NCAA college basketball game against the Baylor Saturday, March 8, 2025, in Waco, Texas.
(AP Photo/Julio Cortez)
  • Houston has reached the Sweet 16 in five consecutive NCAA Tournaments.
  • Houston is currently fourth in the national championship odds table.

Houston menโ€™s basketball has become a national power under head coach Kelvin Sampson, reaching the second weekend of March Madness in five consecutive tournaments dating back to 2019.ย 

Once again, Houston is considered one of the top national contenders in BetMGMโ€™s 2025 college basketball futures market.ย 

I have much more national analysis in my March Madness odds article, which I recommend you read as a helpful guide to betting the NCAA Tournament.ย 

But for anyone whoโ€™s focused on the Cougars specifically, hereโ€™s a look at the Houston basketball odds market.ย ย 

Houston March Madness Odds

Round ReachedMarch Madness Odds
National Championship+700
Final Four+150
Sweet 16TBD
Round of 32TBD

Houston National Championship Odds

Houston menโ€™s basketball is +700 to win the 2025 national championship.ย 

Houston Final Four Odds

Houston menโ€™s basketball is +150 to reach the 2025 Final Four.ย 

Houston NCAA Tournament Odds

Houstonโ€™s first NCAA Tournament game will be either March 20 or March 21.

You can check out my breakdown of the full NCAA Tournament schedule right at that link.ย 

Mar 20 - 1 pm EST

SIU Edwardsville at Houston U

Spread
Totals
Money Line (US)
SIU Edwardsville
Houston U

College Basketball Betting Lines

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About the Author

Chase Kiddy

Read More @chaseakiddy

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.