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The last time Purdue made the Final Four was in the 1979-80 season when the Boilermakers lost to UCLA 67-62.
Led by head coach Lee Rose, Purdue went 23-10 in the regular season and enjoyed a deep run in the tournament before bowing out a few wins shy of a national title.
The 2023 Final Four will be at NRG Stadium in Houston.
Purdue NCAA Tournament History
| Year | NCAA Tournament Result |
| 2021-22 | Lost NCAA Tournament Regional Semifinal |
| 2020-21 | Lost NCAA Tournament First Round |
| 2019-20 | Did Not Qualify |
| 2018-19 | Lost NCAA Tournament Regional Final |
| 2017-18 | Lost NCAA Tournament Regional Semifinal |
| 2016-17 | Lost NCAA Tournament Regional Semifinal |
| 2015-16 | Lost NCAA Tournament First Round |
| 2014-15 | Lost NCAA Tournament Second Round |
| 2013-14 | Did Not Qualify |
| 2012-13 | Did Not Qualify |
| 2011-12 | Lost NCAA Tournament Third Round |
| 2010-11 | Lost NCAA Tournament Third Round |
| 2009-10 | Lost NCAA Tournament Regional Semifinal |
| 2008-09 | Lost NCAA Tournament Regional Semifinal |
| 2007-08 | Lost NCAA Tournament Second Round |
| 2006-07 | Lost NCAA Tournament Second Round |
| 2005-06 | Did Not Qualify |
| 2004-05 | Did Not Qualify |
| 2003-04 | Did Not Qualify |
| 2002-03 | Lost NCAA Tournament Second Round |
| 2001-02 | Did Not Qualify |
| 2000-01 | Did Not Qualify |
| 1999-00 | Lost NCAA Tournament Regional Final |
| 1998-99 | Lost NCAA Tournament Regional Semifinal |
| 1997-98 | Lost NCAA Tournament Regional Semifinal |
| 1996-97 | Lost NCAA Tournament Second Round |
| 1995-96 | Lost NCAA Tournament Second Round* |
| 1994-95 | Lost NCAA Tournament Second Round |
| 1993-94 | Lost NCAA Tournament Regional Final |
| 1992-93 | Lost NCAA Tournament First Round |
| 1991-92 | Did Not Qualify |
| 1990-91 | Lost NCAA Tournament First Round |
| 1989-90 | Lost NCAA Tournament Second Round |
| 1988-89 | Did Not Qualify |
| 1987-88 | Lost NCAA Tournament Regional Semifinal |
| 1986-87 | Lost NCAA Tournament Second Round |
| 1985-86 | Lost NCAA Tournament First Round |
| 1984-85 | Lost NCAA Tournament First Round |
| 1983-84 | Lost NCAA Tournament Second Round |
| 1982-83 | Lost NCAA Tournament Second Round |
| 1981-82 | Did Not Qualify |
| 1980-81 | Did Not Qualify |
| 1979-80 | Lost NCAA Tournament National Semifinal |
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