Duke opens the 2026 football season against Tulane at home. The Blue Devils went 9-5 last year, including 7-2 in the ACC.
Current 2026 Win Total Odds
Duke’s win total for 2026 is 5.5.
The Blue Devils have won at least eight games the past four seasons. The last time they failed to win eight games was 2021 (3-9).
2026 Duke Blue Devils Football Schedule
Duke’s non-conference schedule begins in Week 1 with a home game vs. Tulane . The Blue Devils road opener is a week later, a non-conference game against Illinois.
Duke’s first conference game is a Sept. 19 matchup vs. Stanford.
Non-Conference Matchups
- Sept. 5: vs. Tulane
- Sept. 12: at Illinois
- Sept. 26: vs. William & Mary
Of Duke’s non-conference opponents, Tulane won the most games in 2025; the Green Wave went 11-3.
ACC Matchups
- Sept. 19: vs. Stanford
- Oct. 10: at Georgia Tech
- Oct. 17: vs. North Carolina
- Oct. 23: at Virginia
- Oct. 31: vs. Boston College
- Nov. 7: at NC State
- Nov. 14: at Miami
- Nov. 20: vs. Clemson
- Nov. 28: at Wake Forest
Of Duke’s conference opponents, Miami won the most games; the Hurricanes went 13-3, including 6-2 in the ACC.
2025 Duke Football Results
Duke went 7-5 during the 2025 regular season. They went on to beat Virginia in the ACC Championship, and also defeated Arizona State in the Tony The Tiger Sun Bowl to finish 9-5.
- Aug. 28: vs. Elon – Win (45-17)
- Sept. 6: vs. Illinois – Loss (45-19)
- Sept. 13: at Tulane – Loss (34-27)
- Sept. 20: vs. NC State – Win (45-33)
- Sept. 27: at Syracuse – Win (38-3)
- Oct. 4: at California – Win (45-21)
- Oct. 18: vs. Georgia Tech – Loss (27-18)
- Nov. 1: vs. at Clemson – Win (46-45)
- Nov. 8: at UConn – Loss (37-34)
- Nov. 15: vs. Virginia – Loss (34-17)
- Nov. 22: at North Carolina – Win (32-25)
- Nov. 29: vs. Wake Forest – Win (49-32)
- Dec. 6: vs. Virginia* – Win (27-20)(OT)
- Dec. 31: vs. Arizona State* – Win (42-39)
*neutral site
Visit the online sportsbook to bet on Duke football odds and more college football odds throughout the year.
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