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Find out which 13 NFL teams have won a game as underdogs of at least 14 points. Read More
Get information about the current Buffalo Bills defensive coordinator, along with his past roles in the NFL. Read More
See the latest NFL Week 1 odds, picks and predictions for Bills vs. Ravens on September 7 at Highmark Stadium. Read More
Get information about the Buffalo Billsโ offensive coordinator, along with past NFL roles. Read More
Get the latest 2025 Bills over under wins for their NFL season win total, along with their 2025 win total odds and win total predictions. Read More
Get my AFC East prediction, along with AFC East odds and standings, for the 2025 division winner based on NFL odds at BetMGM. Read More
Bet on the regular-season passing yards and touchdown totals for Buffalo Bills quarterback Josh Allen. Read More
Who is the Buffalo Billsโ backup QB? Get the information on Josh Allenโs backup, along with stats and betting info. Read More
Get implied probability for the Buffalo Bills playoff chances based on both preseason and live NFL odds for the 2025-26 NFL season. Read More
BetMGM has updated NFL odds for the Buffalo Bills, including spreads, futures, and more.
If youโre in New York, check out updated New York sportsbook promos for a potential Odds Boost, Parlay Boost, and more!
Will the Bills win the division? Will an edge rusher go over his regular-season sacks total? How many wins will they have in the regular season?
For example: If you bet $10 on a player to go over his regular-season sacks total, the bet would settle when that player exceeds the total or ends the regular-season under the total.
Log in to your account today for updated Super Bowl odds and more futures.
When you bet on a Bills spread, youโre betting on the final margin of the game.
For example: If you bet $35 on the Bills -11.5 (-110) against the New England Patriots, Buffalo must win the game by at least 12 points.
Alternatively, if you bet $35 on the Bills +5.5 (-105) against the New York Jets, Buffalo must lose by five or fewer points (or win the game).
If the scoring margin is identical to the spread (e.g., -3 or +6), the bet is aย push, and your money is refunded.
Will the Bills win the game? The margin of victory doesn’t matter in moneyline betting.
For example: If you bet $55 on the Bills -150 against the Arizona Cardinals, Buffalo must win the game.
If the game ends in a tie, the bet is a push.
How many combined points will be scored by both teams? The final result (win, loss, or tie) of the game is irrelevant.
For example: If you bet $100 on over 50.5 (-110) in the Billsโ game against the Cincinnati Bengals, the teams must combine for at least 51 points.
Alternatively, if you bet $100 on under 50.5 (-110), the teams must combine for 50 or fewer points.
If the combined point total is identical to the over/under total, the bet is a push.
You can combine Bills bets and other bets (NFL, NBA, or another sport) into one parlay for more entertainment and a bigger potential payout.
For example: If you bet $15 on a two-leg parlay with the Bills’ moneyline (-150) against the Cleveland Browns and the Tennessee Titans’ moneyline (+120) against the Chicago Bears, both legs must hit for the parlay to cash.
If one bet is a push, itโs eliminated from the parlay, and odds (and payout) are recalculated without that leg. You can alsoย Cash Out early on a parlay betย (if available).
You can also build multi-sportย parlaysย andย NFL teaser betsย with odds from NFL games, MLB games, and more. And BetMGM offers theย best sportsbook promotionsย for parlays.
How many passing touchdowns will a quarterback have in the game? Will the quarterback have at least one rushing touchdown?
BetMGM offers dozens of prop bets for each NFL game, including player prop bets for yardage totals, touchdowns, field goals, and more.
Read the latest betting tips and how-to guides from BetMGM experts.
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