Iowa State vs Arizona Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 8

Arizona football stadium
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Week 8 Odds Boost
  • The Arizona Wildcats are a -10 point favorite vs. the Iowa State Cyclones
  • Iowa State vs. Arizona Total (Over/Under): 50.5 points
  • TV Channel: ESPN2

Iowa State (3-3) visit Casino Del Sol Stadium to take on Arizona (5-1) on Oct. 24 in Tucson, AZ. Kickoff is scheduled for 7:30 pm.

The Arizona Wildcats are betting favorites in Week 8, with the spread sitting at -10 (-108).

The Iowa State vs. Arizona Over/Under is 50.5 total points.

Bet now on Arizona Wildcats vs Iowa State Cyclones & all NCAAF games with BetMGM

Iowa State vs. Arizona Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Iowa State+10 -11050.5 -108+260
Arizona -10 -10850.5 -110-325

Iowa State vs Arizona Prediction:

The winning team model predicts Arizona will win this game with 71.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.

The winning team prediction factors in up-to-date player injuries for both the Iowa State Cyclones and the Arizona Wildcats, key player performances this season and recent team trends.

Iowa State vs Arizona Spread Prediction:

Based on recent against-the-spread trends, the model predicts Arizona will cover the spread with 66.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Arizona Wildcats vs Iowa State Cyclones and all games with BetMGM


  • Iowa State has hit the 1Q Moneyline in 6 of their last 11 games (+4.65 Units / 16% ROI)
  • Iowa State has hit the 1H Moneyline in 7 of their last 11 games (+3.30 Units / 3% ROI)
  • Iowa State has hit the Game Total Under in 7 of their last 11 games (+2.62 Units / 22% ROI)
  • Iowa State have covered the 1H Spread in 7 of their last 11 games (+2.55 Units / 20% ROI)
  • Iowa State has hit the Team Total Under in 7 of their last 11 games (+2.50 Units / 20% ROI)
  • Arizona has hit the Moneyline in 8 of their last 10 games (+6.75 Units / 36% ROI)
  • Arizona has hit the 1Q Game Total Over in 9 of their last 12 games (+5.95 Units / 43% ROI)
  • Arizona has hit the Game Total Under in 8 of their last 12 games (+3.60 Units / 27% ROI)
  • Arizona has hit the 1H Game Total Over in 7 of their last 12 games (+1.05 Units / 7% ROI)
  • Arizona has hit the Team Total Under in 3 of their last 5 games at home (+0.65 Units / 11% ROI)

Iowa State Against the Spread (ATS) Record

Iowa State Cyclones is 2-3 against the spread this college football season (-1.34 Units / -20.03% ROI).

  • Iowa State is 3-3 when betting on the Moneyline for +0 Units / 0% ROI
  • Iowa State is 3-3 when betting the Over for -0.28 Units / -4.24% ROI
  • Iowa State is 3-3 when betting the Under for -0.28 Units / -4.24% ROI

Arizona Against the Spread (ATS) Record

Arizona Wildcats is 2-4 against the spread this college football season (-2.3 Units / -35.66% ROI).

  • Arizona is 3-1 when betting on the Moneyline for +2 Units / 21.16% ROI
  • Arizona is 3-3 when betting the Over for -0.3 Units / -4.55% ROI
  • Arizona is 3-3 when betting the Under for -0.3 Units / -4.55% ROI

Iowa State: Keys to the Game vs. Arizona

Iowa State was 6-1 (.857) when allowing less than 5 yards per rush last season– 11th-best among Power Conference Teams; Average: .647

Iowa State is 2-6 (.250) when intercepting no passes since the 2024 season– T-36th-worst in FBS; Average: .391

Iowa State was 9-3 (.750) when their opponent rushed more than 30 times last season– T-8th-best among Power Conference Teams; Average: .481

Iowa State is 9-3 (.750) when allowing less than 5 yards per rush since the 2024 season– T-29th-best in FBS; Average: .631

Arizona: Keys to the Game vs. Iowa State

Arizona was 1-8 (.111) when averaging less than 5 yards per rush last season– 5th-worst among Power Conference Teams; Average: .462

Arizona was 2-4 (.333) when not forcing and recovering a fumble last season– T-13th-worst among Power Conference Teams; Average: .492

Arizona is 7-5 (.583) when sacking the QB less than 3 times since the 2024 season– T-36th-best in FBS; Average: .434

Arizona was 2-6 (.250) when allowing 200 or more passing yards last season– T-16th-worst in FBS; Average: .481

Matchup Notes for Iowa State vs. Arizona

Arizona’s WRs averaged 25.5 targets per game last season — T-3rd-highest among Power 5 WRs. Iowa State’s defense allowed 13.5 receptions per game to WRs last season — T-31st-worst among FBS defenses.

Arizona’s WRs averaged 25.5 targets per game last season — T-14th-highest among FBS WRs. Iowa State’s defense allowed 13.5 receptions per game to WRs last season — T-31st-worst among FBS defenses.

Arizona has 689 receptions in 31 games (22.2 per game) since the 2024 season — T-26th-best among FBS skill players. Iowa State’s defense has allowed just 16.6 receptions per game since the 2024 season — T-14th-best among FBS defenses.

Iowa State’s TEs had 76 receptions in 12 games (6.3 per game) last season — 2nd-best among P5 TEs. Arizona’s defense allowed just 16.0 receptions per game last season — 3rd-best among Big 12 defenses.

Iowa State’s TEs gained 922 yards on 76 receptions (12.1 YPR) last season — T-5th-best among Big 12 TEs. Arizona’s defense allowed just 10.3 Yards Per Reception last season — 2nd-best among Big 12 defenses.

Iowa State’s TEs had 76 receptions in 12 games (6.3 per game) last season — 2nd-best among FBS TEs. Arizona’s defense allowed just 16.0 receptions per game last season — 3rd-best among Big 12 defenses.

Iowa State Offensive Stats & Trends

Iowa State have thrown 3 TDs on 140 pass attempts (one TD every 46.7 Pass Attempts) in the 4th quarter since the 2024 season– 4th-worst among FBS Offenses; Average: 19.0

Iowa State WRs have no touchdowns on 2 receptions in the Red Zone this season– 2nd-worst Receptions Per TD among Big 12 Teams; Average: 1.6

Iowa State WRs have no touchdowns on 2 receptions in the Red Zone this season– T-2nd-worst Receptions Per TD among Power Conference Teams; Average: 1.8

Iowa State Skill Players have averaged a touchdown every 28.0 receptions (56 Rec/2 TDs) in close and late situations since the 2024 season– worst Receptions Per TD among Big 12 Teams; Average: 10.3

Iowa State threw one TD on 100 pass attempts in the 4th quarter last season– 6th-worst among FBS Offenses; Average: 19.9

Arizona Offensive Stats & Trends

Arizona TEs averaged 23.2 yards per reception (93 yards/4 catches) on 3rd and long last season– best among Big 12 Teams; Average: 12.2

Arizona TEs had no touchdowns on 3 receptions in the Red Zone last season– T-worst Receptions Per TD among Power Conference Teams; Average: 2.0

Arizona TEs had no touchdowns on 3 receptions in the Red Zone last season– worst Receptions Per TD among Big 12 Teams; Average: 1.9

Arizona’s WRs averaged 25.5 targets per game last season — T-3rd-highest among Power 5 WRs. Iowa State’s defense allowed 13.5 receptions per game to WRs last season — T-31st-worst among FBS defenses.

Arizona’s WRs averaged 25.5 targets per game last season — T-14th-highest among FBS WRs. Iowa State’s defense allowed 13.5 receptions per game to WRs last season — T-31st-worst among FBS defenses.

Iowa State Defensive Stats & Trends

Iowa State has not recorded a sack (53 pass attempts) in the Red Zone since the 2024 season– T-worst in FBS; Average: 15.8

Iowa State has sacked opposing QBs on just 4% of pass attempts (22/540) since the 2024 season– worst in the Big 12; Average: 7%

Iowa State has not recorded a sack (53 pass attempts) in the Red Zone since the 2024 season– worst in the Big 12; Average: 18.7

Iowa State allowed a Completion Pct of just 41% (21 completions/51 attempts) when opponents had over 10 yards to go in the 2023 season– best in the Big 12; Average: 61%

Iowa State has not recorded a sack (53 pass attempts) in the Red Zone since the 2024 season– T-worst among Power Conference Teams; Average: 15.9

Arizona Defensive Stats & Trends

Arizona opponents has averaged 41.5 Passing Attempts per TD (581 Pass Attempts/14 Passing TDs) since the 2024 season– 3rd-best in FBS; Average: 21.3

Arizona opponents has averaged 6.7 Passing Attempts per TD (47 Pass Attempts/7 Passing TDs) in the Red Zone since the 2024 season– best among Power Conference Teams; Average: 3.9

Arizona has allowed a Completion Pct of just 38% (3 completions/8 attempts) on 3rd and short this season– 2nd-best in the Big 12; Average: 64%

Arizona opponents averaged 42.6 Passing Attempts per TD (383 Pass Attempts/9 Passing TDs) last season– 5th-best in FBS; Average: 21.3

The Arizona defense has allowed scores on 15% of opponent drives (22/148) in the 2nd half since the 2024 season– 5th-best in FBS; Average: 23%


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