Angels vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, Apr 29

Chicago White Sox first base Miguel Vargas (20) during their spring training baseball game against the Los Angeles Dodgers, Saturday, March 8, 2025, in Phoenix.
(AP Photo/Darryl Webb)
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  • The Angels are -120 favorites vs the White Sox
  • Angels vs White Sox Over / Under today: 8.5 Runs
  • Angels / White Sox TV Channel: FDW | CHSN

The Los Angeles Angels (-120) visit Rate Field to take on the Chicago White Sox (+100) on April 29, 2026. First pitch is scheduled for 1:10 pm in Chicago, IL.

This season, the Angels are 12-19 against the spread (ATS), while the White Sox are 14-16 ATS.

Angels vs White Sox Starting Pitchers Today:

  • Angels starting pitcher: Yusei Kikuchi 0-3, 6.14 ERA
  • White Sox starting pitcher: Erick Fedde 0-3, 3.46 ERA

Angels vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels-1.5 +140O 8.5 -105-120
White Sox +1.5 -170U 8.5 -115+100

Angels vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Angels will win Wednesday‘s MLB game with 52.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Josh Lowe has hit the Home Runs Over in 3 of his last 10 games (+13.10 Units / 131% ROI)
  • Jo Adell has hit the Singles Over in 15 of his last 20 away games (+12.80 Units / 63% ROI)
  • Jo Adell has hit the RBIs Over in 8 of his last 10 away games (+10.85 Units / 109% ROI)
  • Yusei Kikuchi has hit the Walks Allowed Over in 13 of his last 15 away games (+10.70 Units / 49% ROI)
  • Jorge Soler has hit the Total Bases Over in 18 of his last 25 games (+10.20 Units / 31% ROI)

And here are some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Miguel Vargas has hit the Home Runs Over in 4 of his last 9 games (+17.00 Units / 189% ROI)
  • Miguel Vargas has hit the Walks Over in 14 of his last 20 games (+12.70 Units / 63% ROI)
  • Chase Meidroth has hit the Runs Over in 12 of his last 20 games at home (+9.70 Units / 49% ROI)
  • Luisangel Acuna has hit the Hits Under in 15 of his last 25 games (+9.25 Units / 37% ROI)
  • Miguel Vargas has hit the Singles Under in 19 of his last 25 games at home (+9.25 Units / 23% ROI)
  • The Los Angeles Angels have hit the Team Total Under in 31 of their last 50 games (+9.80 Units / 16% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 22 games (+9.05 Units / 33% ROI)
  • The Los Angeles Angels have hit the Game Total Over in 29 of their last 50 away games (+7.10 Units / 13% ROI)
  • The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 19 of their last 30 games (+5.80 Units / 16% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 14 of their last 30 games (+4.60 Units / 14% ROI)
  • The Chicago White Sox have hit the Team Total Over in 9 of their last 11 games (+7.05 Units / 56% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 games at home (+6.15 Units / 10% ROI)
  • The Chicago White Sox have hit the Game Total Over in 21 of their last 35 games (+5.70 Units / 15% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 21 of their last 50 games at home (+5.60 Units / 11% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 6 of their last 7 games at home (+5.00 Units / 56% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 15-16 against the Run Line (-6.2 Units / -14.94% ROI).

  • 12-19 when betting on the Moneyline for -2.85 Units / -8.7% ROI
  • 17-13 when betting on the total runs Over for +2.95 Units / 8.58% ROI
  • 13-17 when betting on the total runs Under for -5.2 Units / -15.38% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 14-16 against the Run Line (-8.55 Units / -19.88% ROI).

  • 13-17 when betting on the Moneyline for -0.8 Units / -2.57% ROI
  • 18-12 when betting on the total runs Over for +4.9 Units / 14.92% ROI
  • 12-18 when betting on the total runs Under for -7.85 Units / -23.68% ROI

White Sox vs Angels Home Run Prop Bets Today

Yes
Mike Trout +310
Munetaka Murakami +310
Jo Adell +390
Colson Montgomery +400
Zachary Neto +400

White Sox vs Angels Total Hits Prop Bets Today

Over Under
Chase Meidroth 0.5 -220 0.5 +160
Zachary Neto 0.5 -210 0.5 +155
Nolan Schanuel 0.5 -190 0.5 +140
Mike Trout 0.5 -185 0.5 +135
Jo Adell 0.5 -185 0.5 +135

White Sox vs Angels Strikeout Prop Bets Today

Over Under
Derek Hill 0.5 -275 0.5 +200
Travis d'Arnaud 0.5 -250 0.5 +185
Jo Adell 0.5 -220 0.5 +165
Josh Lowe 0.5 -210 0.5 +155
Miguel Vargas 0.5 -175 0.5 +130

Angels Keys to the Game vs. the White Sox

The Angels are just 0-15 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .053.

The Angels are just 0-12 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .145.

The Angels are just 25-32 (.439) vs the bottom 10 runs allowed teams since the 2025 season Today, they face the White Sox (27th runs allowed).

The Angels are just 81-95 (.460) when allowing 5 or more extra base hits since the 2025 season — 4th lowest in MLB; League Avg: .534.

White Sox Keys to the Game vs. the Angels

The White Sox are just 56-18 (.757) when leading entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .872.

The White Sox are just 66-7 (.904) when leading entering the 9th inning since the 2025 season — lowest in MLB; League Avg: .955.

The White Sox are just 20-103 (.163) when scoring 4 or fewer runs since the 2025 season — lowest in MLB; League Avg: .284.

The White Sox are just 110-204 (.350) when allowing 5 or more extra base hits since the 2024 season — lowest in MLB; League Avg: .536.

Angels hitters have struck out in 27% of their PA’s against RHP since the 2025 season — highest in MLB.

The Angels are batting just .121 on pitches out of the zone since the 2025 season — lowest in MLB.

Angels hitters have struck out in 27% of their PA’s since the 2025 season — highest in MLB.

Angels hitters have struck out in 26% of their PA’s against RHP this season — highest in MLB.

White Sox hitters are slugging just .363 against RHP since the 2025 season — 2nd lowest in MLB.

White Sox hitters have an OPS of just .668 (5,256 PA’s) against RHP since the 2025 season — lowest in MLB.

White Sox hitters have a groundball batting average of just .220 with runners on base since the 2025 season — lowest in MLB.

White Sox hitters have an OBP of just .295 (855 PA’s) when facing the starting pitcher for the 3rd time in a game since the 2025 season — lowest in MLB.

Angels pitchers have walked 10% of batters since the 2025 season — highest in MLB.

Angels pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — highest in MLB.

Angels pitchers have a first-pitch strike rate of just 56% this season — lowest in MLB.

Opponents have a miss rate of 28% against Angels pitchers this season — best in MLB.

White Sox pitchers have walked 14% of batters when facing the leadoff batter in the inning this season — highest in MLB.

White Sox pitchers have walked 10% of batters since the 2025 season — 2nd highest in MLB.

White Sox pitchers have a strikeout rate of just 38% with two-strikes this season — 3rd lowest in MLB.

Opponents have a miss rate of just 22% against White Sox pitchers this season — 3rd lowest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.