• The Mariners are -150 favorites vs the Astros
• Astros vs Mariners Over / Under today: 7.5 Runs
• Astros / Mariners TV Channel: MRTV | SCHN | ESUN

The Houston Astros (+125) visit T-Mobile Park to take on the Seattle Mariners (-150) on April 11, 2026. First pitch is scheduled for 9:40 pm in Seattle, WA.

This season, the Astros are 6-8 against the spread (ATS), while the Mariners are 5-9 ATS.

Astros vs Mariners Starting Pitchers Today:

• Astros starting pitcher: Lance McCullers 1-0, 3.27 ERA
• Mariners starting pitcher: Luis Castillo 0-0, 2.90 ERA

Astros vs. Mariners Odds, Run Line, Over/Under & Moneyline

Astros vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Saturday‘s MLB game with 60.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Mariners and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Yordan Alvarez has hit the Hits Under in 14 of his last 20 away games (+11.00 Units / 35% ROI)
• Cam Smith has hit the Home Runs Over in 2 of his last 8 games (+10.50 Units / 131% ROI)
• Carlos Correa has hit the Runs Over in 15 of his last 25 away games (+8.85 Units / 35% ROI)
• Jose Altuve has hit the Total Bases Under in 18 of his last 25 away games (+8.20 Units / 22% ROI)
• Yainer Diaz has hit the RBIs Over in 8 of his last 15 away games (+6.50 Units / 43% ROI)

And here are some favorite MLB player prop bets for Mariners players for Saturday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

• Julio Rodriguez has hit the Total Bases Under in 20 of his last 25 games (+13.45 Units / 36% ROI)
• Luke Raley has hit the Home Runs Over in 2 of his last 5 games at home (+12.50 Units / 250% ROI)
• Julio Rodriguez has hit the Hits Under in 14 of his last 25 games (+9.35 Units / 31% ROI)
• Dominic Canzone has hit the Runs Over in his last 5 games at home (+9.25 Units / 185% ROI)
• J.P. Crawford has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+8.55 Units / 66% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 18 games (+7.90 Units / 39% ROI)
• The Houston Astros have hit the Game Total Over in 10 of their last 12 games (+7.80 Units / 58% ROI)
• The Houston Astros have hit the Team Total Over in 9 of their last 12 games (+5.00 Units / 32% ROI)
• The Houston Astros have covered the Run Line in 27 of their last 50 away games (+3.75 Units / 6% ROI)
• The Houston Astros have covered the 1st Five Innings (F5) Run Line in 19 of their last 35 away games (+0.80 Units / 2% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Moneyline in 34 of their last 50 games at home (+12.35 Units / 15% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 24 of their last 40 games at home (+9.85 Units / 14% ROI)
• The Seattle Mariners have hit the Team Total Over in 24 of their last 40 games at home (+6.35 Units / 14% ROI)
• The Seattle Mariners have hit the Game Total Over in 23 of their last 40 games at home (+5.65 Units / 13% ROI)
• The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games at home (+5.00 Units / 10% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 6-8 against the Run Line (-1.15 Units / -7.21% ROI).

• 6-8 when betting on the Moneyline for -5.1 Units / -26.77% ROI
• 10-4 when betting on the total runs Over for +5.5 Units / 35.03% ROI
• 4-10 when betting on the total runs Under for -6.8 Units / -45.03% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 5-9 against the Run Line (-4 Units / -24.77% ROI).

• 5-9 when betting on the Moneyline for -7.4 Units / -37.95% ROI
• 6-8 when betting on the total runs Over for -2.8 Units / -18.18% ROI
• 8-6 when betting on the total runs Under for +1.4 Units / 9.09% ROI

Astros Keys to the Game vs. the Mariners

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros are just 0-7 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .027.

The Astros were 71-4 (.947) when leading entering the 8th inning in the 2025 season — tied for 2nd best in MLB; League Avg: .909.

The Astros were 12-6 (.667) when tied entering the 7th inning in the 2025 season — 3rd best in MLB; League Avg: .500.

Mariners Keys to the Game vs. the Astros

The Mariners are just 5-9 (.357) this season — tied for 2nd lowest in MLB; League Avg: .500.

The Mariners are just 11-27 (.289) vs top 10 scoring offenses since the 2025 season Today, they face the Astros (second in runs scored).

The Mariners were 5-59 (.078) when trailing entering the 9th inning in the 2025 season — 5th best in MLB; League Avg: .043.

The Mariners were 70-3 (.959) when leading entering the 8th inning in the 2025 season — best in MLB; League Avg: .909.

Astros Hitting Stats & Trends

Astros hitters have an OBP of .516 (62 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .383 (360 PA’s) against RHP this season — best in MLB.

Astros hitters have an OBP of .372 (566 PA’s) this season — best in MLB.

The Astros are batting .388 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Mariners Hitting Stats & Trends

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

Mariners hitters are slugging just .230 on the road this season — lowest in MLB.

The Mariners are batting just .227 when facing the starting pitcher for the 3rd time in a game since the 2024 season — lowest in MLB.

Mariners hitters are slugging just .217 against LHP this season — 2nd lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 14% of batters this season — highest in MLB.

Astros pitchers have an ERA of 6.32 (121.0 IP) this season — highest in MLB.

Opponents have a groundball batting average of .346 against Astros pitchers this season — highest in MLB.

The Astros have allowed 4.21 runs per game (59/14) in the first 5 innings this season — highest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have induced opposing hitters to ground into 17 double plays in 72 opportunities (24%) this season — best in MLB.

Mariners pitchers have walked 6% of batters this season — 2nd best in MLB.

The Mariners pitchers have allowed division opponents to score first in just 31% of their games since the 2024 season — lowest in MLB.

Mariners pitchers have walked 7% of batters since the 2024 season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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