• The Reds are -145 favorites vs the Astros
• Astros vs Reds Over / Under today: 9 Runs
• Astros / Reds TV Channel: RDTV | SCHN

The Houston Astros (+120) visit Great American Ball Park to take on the Cincinnati Reds (-145) on May 8, 2026. First pitch is scheduled for 6:10 pm in Cincinnati, OH.

This season, the Astros are 15-23 against the spread (ATS), while the Reds are 23-14 ATS.

Astros vs Reds Starting Pitchers Today:

• Astros starting pitcher: Michael Burrows 1-4, 5.98 ERA
• Reds starting pitcher: Nick Lodolo 0-0, 0.00 ERA

Astros vs. Reds Odds, Run Line, Over/Under & Moneyline

Astros vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Friday‘s MLB game with 53.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Astros vs Reds and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

• Brice Matthews has hit the Home Runs Over in 3 of his last 8 games (+14.90 Units / 186% ROI)
• Yordan Alvarez has hit the Runs Under in 18 of his last 25 away games (+11.80 Units / 41% ROI)
• Christian Walker has hit the Total Bases Over in 17 of his last 25 away games (+11.15 Units / 40% ROI)
• Isaac Paredes has hit the Singles Over in 11 of his last 15 away games (+8.40 Units / 54% ROI)
• Isaac Paredes has hit the Hits Over in 12 of his last 15 away games (+8.30 Units / 34% ROI)

And here are some favorite MLB player prop bets for Reds players for Friday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

• Nate Lowe has hit the Home Runs Over in 4 of his last 6 games at home (+20.30 Units / 338% ROI)
• Tyler Stephenson has hit the Runs Under in 18 of his last 20 games (+13.90 Units / 35% ROI)
• Matt McLain has hit the Singles Under in 20 of his last 25 games at home (+12.95 Units / 34% ROI)
• TJ Friedl has hit the Walks Under in 17 of his last 20 games (+12.25 Units / 35% ROI)
• Nate Lowe has hit the Total Bases Over in 18 of his last 25 games (+11.70 Units / 35% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Game Total Over in 24 of their last 35 games (+12.60 Units / 32% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 40 games (+9.70 Units / 21% ROI)
• The Houston Astros have hit the Team Total Under in 7 of their last 9 games (+4.25 Units / 36% ROI)
• The Houston Astros have hit the Moneyline in 3 of their last 5 games (+2.50 Units / 50% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 5 of their last 9 away games (+1.50 Units / 16% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the Game Total Over in 12 of their last 14 games at home (+9.75 Units / 63% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 22 games at home (+6.45 Units / 23% ROI)
• The Cincinnati Reds have covered the Run Line in 14 of their last 22 games (+5.05 Units / 16% ROI)
• The Cincinnati Reds have hit the Team Total Under in 14 of their last 22 games at home (+4.80 Units / 18% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 24 of their last 50 games at home (+4.05 Units / 6% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 15-23 against the Run Line (-10.45 Units / -21.88% ROI).

• 15-23 when betting on the Moneyline for -10.4 Units / -22.46% ROI
• 25-12 when betting on the total runs Over for +11.3 Units / 26.49% ROI
• 12-25 when betting on the total runs Under for -15.2 Units / -37.07% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 23-14 against the Run Line (+4.4 Units / 7.72% ROI).

• 20-18 when betting on the Moneyline for +2.3 Units / 5.43% ROI
• 23-14 when betting on the total runs Over for +7.6 Units / 18.18% ROI
• 14-23 when betting on the total runs Under for -11.3 Units / -27.03% ROI

Reds vs Astros Home Run Prop Bets Today

Reds vs Astros Total Hits Prop Bets Today

Reds vs Astros Strikeout Prop Bets Today

Astros Keys to the Game vs. the Reds

The Astros are just 0-21 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .107.

The Astros are just 1-15 (.062) when allowing 10 or more hits this season — lowest in MLB; League Avg: .244.

The Astros are just 0-19 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .140.

The Astros are just 6-13 (.316) on the road this season — tied for 2nd lowest in MLB; League Avg: .467.

Reds Keys to the Game vs. the Astros

The Reds are 3-16 (.158) when trailing entering the 9th inning this season — 2nd best in MLB; League Avg: .053.

The Reds are 4-12 (.250) when trailing entering the 7th inning this season — tied for 3rd best in MLB; League Avg: .140.

The Reds are just 12-45 (.211) when allowing 10 or more hits since the 2025 season — 5th lowest in MLB; League Avg: .254.

The Reds are just 10-64 (.135) when allowing 5 or more runs since the 2025 season — 5th lowest in MLB; League Avg: .204.

Astros Hitting Stats & Trends

Astros hitters are slugging .434 against RHP this season — 4th best in MLB.

Astros hitters have an OBP of .412 (160 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .359 (768 PA’s) on the road this season — 2nd best in MLB.

The Astros are batting .288 on the road this season — 2nd best in MLB.

Reds Hitting Stats & Trends

The Reds are batting just .196 with runners on base this season — lowest in MLB.

Reds hitters have an OBP of just .282 (636 PA’s) with runners on base this season — lowest in MLB.

The Reds are batting just .188 with two outs this season — 2nd lowest in MLB.

The Reds are batting just .120 on pitches out of the zone this season — tied for lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 13% of batters this season — highest in MLB.

Astros pitchers have an ERA of 5.82 (332.1 IP) this season — highest in MLB.

The Astros have allowed 3.76 runs per game (143/38) in the first 5 innings this season — highest in MLB.

Astros pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

Reds Pitching Stats & Trends

Reds pitchers have a first-pitch strike rate of just 56% this season — lowest in MLB.

Reds pitchers have a strike rate of just 60% this season — lowest in MLB.

Reds pitchers have walked 12% of batters this season — 2nd highest in MLB.

Reds pitchers have an ERA of 6.67 (86.1 IP) against division opponents this season — 3rd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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