• The Brewers are -118 favorites vs the Cardinals
• Brewers vs Cardinals Over / Under today: 8.5 Runs
• Brewers / Cardinals TV Channel: FS1 | CATV | BRTV

The Milwaukee Brewers (-118) visit Busch Stadium to take on the St. Louis Cardinals (-102) on May 4, 2026. First pitch is scheduled for 7:45 pm in St. Louis, MO.

This season, the Brewers are 18-15 against the spread (ATS), while the Cardinals are 21-12 ATS.

Brewers vs Cardinals Starting Pitchers Today:

• Brewers starting pitcher: Chad Patrick 2-1, 2.57 ERA
• Cardinals starting pitcher: Kyle Leahy 3-3, 5.59 ERA

Brewers vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Brewers vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Monday‘s MLB game with 52.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Brewers vs Cardinals and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Brewers players for Monday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

• Sal Frelick has hit the Home Runs Over in 2 of his last 5 games (+16.00 Units / 320% ROI)
• Brice Turang has hit the Hits Under in 15 of his last 25 away games (+12.15 Units / 41% ROI)
• Brice Turang has hit the Total Bases Under in 18 of his last 25 away games (+9.70 Units / 26% ROI)
• William Contreras has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+9.20 Units / 29% ROI)
• Garrett Mitchell has hit the Walks Over in 7 of his last 9 away games (+9.05 Units / 101% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Monday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• JJ Wetherholt has hit the Home Runs Over in 4 of his last 9 games (+26.10 Units / 290% ROI)
• Jordan Walker has hit the Runs Over in 17 of his last 25 games (+15.60 Units / 62% ROI)
• Ramon Urias has hit the Singles Under in 16 of his last 20 games (+11.00 Units / 41% ROI)
• Jordan Walker has hit the Hits Over in 20 of his last 25 games (+10.45 Units / 21% ROI)
• Ramon Urias has hit the Total Bases Under in 12 of his last 15 games (+9.35 Units / 44% ROI)

Brewers Best Bets Today:

• The Milwaukee Brewers have covered the Run Line in 25 of their last 45 games (+9.15 Units / 17% ROI)
• The Milwaukee Brewers have hit the Team Total Under in 19 of their last 30 away games (+6.25 Units / 17% ROI)
• The Milwaukee Brewers have hit the Game Total Under in 15 of their last 24 away games (+5.25 Units / 20% ROI)
• The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 28 of their last 50 away games (+4.65 Units / 8% ROI)
• The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 17 of their last 30 games (+3.90 Units / 11% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Moneyline in 25 of their last 45 games (+9.85 Units / 22% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 45 games at home (+9.10 Units / 17% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 10 of their last 16 games (+8.35 Units / 51% ROI)
• The St. Louis Cardinals have covered the Run Line in 14 of their last 18 games (+8.10 Units / 29% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 30 of their last 50 games at home (+7.10 Units / 12% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 20-13 against the Run Line (+10.5 Units / 27.2% ROI).

• 18-15 when betting on the Moneyline for -2.1 Units / -4.79% ROI
• 17-16 when betting on the total runs Over for -0.65 Units / -1.78% ROI
• 16-17 when betting on the total runs Under for -2.6 Units / -7.18% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 21-12 against the Run Line (+3.8 Units / 7.57% ROI).

• 20-14 when betting on the Moneyline for +9.8 Units / 28.32% ROI
• 18-15 when betting on the total runs Over for +1.45 Units / 3.89% ROI
• 15-18 when betting on the total runs Under for -5.05 Units / -13.43% ROI

Cardinals vs Brewers Home Run Prop Bets Today

Cardinals vs Brewers Total Hits Prop Bets Today

Cardinals vs Brewers Strikeout Prop Bets Today

Brewers Keys to the Game vs. the Cardinals

The Brewers are 86-9 (.905) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .794.

The Brewers are 36-28 (.562) vs top 10 scoring offenses since the 2025 season Today, they face the Cardinals (eighth in runs scored).

The Brewers are 53-43 (.552) on the road since the 2025 season — 2nd best in MLB; League Avg: .459.

The Brewers are 9-64 (.123) when trailing entering the 8th inning since the 2025 season — 5th best in MLB; League Avg: .094.

Cardinals Keys to the Game vs. the Brewers

The Cardinals are 2-12 (.143) when trailing entering the 9th inning this season — 4th best in MLB; League Avg: .056.

The Cardinals are 14-5 (.737) vs top 10 scoring offenses this season Today, they face the Brewers (third in runs scored).

The Cardinals are 7-6 (.538) vs the top 10 runs allowed teams this season Today, they face Brewers (fifth in runs allowed).

The Cardinals are 79-5 (.940) when leading entering the 8th inning since the 2025 season — 5th best in MLB; League Avg: .906.

Brewers Hitting Stats & Trends

Brewers hitters have chased just 19% pitches with the pitcher behind in the count since the 2025 season — lowest in MLB.

Brewers hitters have chased 19% of pitches out of the zone in non-two strike counts since the 2025 season — lowest in MLB.

Brewers hitters are slugging just .300 against LHP this season — 2nd lowest in MLB.

Brewers hitters have struck out in just 20% of their PA’s against LHP since the 2025 season — 4th best in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — 3rd best in MLB.

Cardinals hitters have an OPS of just .959 (1,400 PA’s) with the pitcher behind in the count since the 2025 season — lowest in MLB.

Cardinals hitters have struck out in just 12% of their PA’s against LHP over the past seven days (7 games) — best in MLB.

The Cardinals are batting just .211 when facing the starting pitcher for the 3rd time in a game this season — 4th lowest in MLB.

Brewers Pitching Stats & Trends

Brewers pitchers have a strikeout rate of 25% this season — best in MLB.

Brewers pitchers have a strikeout rate of 45% with two-strikes this season — 3rd best in MLB.

Opponents have a miss rate of 27% against Brewers pitchers this season — 5th best in MLB.

Brewers pitchers have a strikeout rate of 24% since the 2025 season — 4th best in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2025 season — lowest in MLB.

Opponents have a miss rate of just 21% against Cardinals pitchers this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 35% with two-strikes this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 18% this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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