Brewers vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Sep 17

Pittsburgh Pirates' Spencer Horwitz rounds the bases after hitting a solo home run in the seventh inning of a baseball game against the Atlanta Braves, Friday, Sept. 26, 2025, in Atlanta. (AP Photo/Colin Hubbard)
(AP Photo/Colin Hubbard)
World Series Betting Promos
  • The Brewers are -145 favorites vs the Pirates
  • Brewers vs Pirates Over / Under today: 9 Runs
  • Brewers / Pirates TV Channel: BRTV | SNPT

The Milwaukee Brewers (-145) visit PNC Park to take on the Pittsburgh Pirates (+120) on September 17, 2026. First pitch is scheduled for 12:35 pm in Pittsburgh, PA.

This season, the Brewers are 95-57 against the spread (ATS), while the Pirates are 72-76 ATS.

Brewers vs Pirates Starting Pitchers Today:

  • Brewers starting pitcher: Kyle Harrison 10-4, 4.01 ERA
  • Pirates starting pitcher: Bladimir Dotel 1-5, 4.84 ERA

Brewers vs. Pirates Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Brewers-1.5 +110O 9 -120-145
Pirates +1.5 -135U 9 +100+120

Brewers vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Thursday‘s MLB game with 55.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Brewers players for Thursday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

  • Jake Bauers has hit the Walks Over in 20 of his last 25 away games (+19.45 Units / 72% ROI)
  • William Contreras has hit the Home Runs Over in 4 of his last 8 games (+17.30 Units / 216% ROI)
  • Joey Ortiz has hit the Total Bases Over in 21 of his last 25 games (+16.20 Units / 41% ROI)
  • Joey Ortiz has hit the Hits Over in 21 of his last 25 games (+14.75 Units / 36% ROI)
  • Luis Lara has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+13.40 Units / 47% ROI)

And here are some favorite MLB player prop bets for Pirates players for Thursday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Nick Gonzales has hit the Runs Under in 18 of his last 20 games (+13.85 Units / 35% ROI)
  • Konnor Griffin has hit the Total Bases Over in 17 of his last 25 games at home (+11.50 Units / 36% ROI)
  • Rafael Flores has hit the Singles Over in 8 of his last 9 games (+9.15 Units / 102% ROI)
  • Rafael Flores has hit the Hits Over in his last 9 games (+9.00 Units / 66% ROI)
  • Rafael Flores has hit the Home Runs Over in 2 of his last 10 games at home (+7.10 Units / 71% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 24 of their last 40 games (+13.15 Units / 21% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 40 games (+10.45 Units / 23% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 26 of their last 40 games (+7.55 Units / 12% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games (+5.95 Units / 13% ROI)
  • The Milwaukee Brewers have hit the Team Total Over in 10 of their last 14 away games (+5.50 Units / 33% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 21 games (+11.80 Units / 49% ROI)
  • The Pittsburgh Pirates have hit the Team Total Under in 31 of their last 50 games (+10.25 Units / 18% ROI)
  • The Pittsburgh Pirates have hit the Game Total Under in 16 of their last 25 games (+9.40 Units / 34% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 6 of their last 8 games (+4.40 Units / 38% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 10 of their last 16 games (+3.55 Units / 17% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 79-73 against the Run Line (+16.7 Units / 9.67% ROI).

  • 95-57 when betting on the Moneyline for +16.3 Units / 7.23% ROI
  • 68-79 when betting on the total runs Over for -18.35 Units / -10.99% ROI
  • 79-68 when betting on the total runs Under for +4.35 Units / 2.59% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 72-76 against the Run Line (-10.15 Units / -5.26% ROI).

  • 75-77 when betting on the Moneyline for -12.55 Units / -6.7% ROI
  • 77-68 when betting on the total runs Over for +2.3 Units / 1.37% ROI
  • 68-77 when betting on the total runs Under for -16.4 Units / -9.82% ROI

Brewers Keys to the Game vs. the Pirates

The Brewers are 15-2 (.882) when tied entering the 7th inning this season — best in MLB.

The Brewers are 20-17 (.541) when their opponents score in the first inning this season — 2nd best in MLB.

The Brewers are 13-44 (.228) when trailing entering the 7th inning this season — best in MLB.

The Brewers are 11-46 (.193) when trailing entering the 8th inning this season — best in MLB.

Pirates Keys to the Game vs. the Brewers

The Pirates are just 6-37 (.140) when allowing 10 or more hits this season — 2nd lowest in MLB.

The Pirates are just 10-24 (.294) when their opponents score in the first inning this season — 5th lowest in MLB.

The Pirates are just 20-124 (.139) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB.

The Pirates are just 23-99 (.189) when allowing 2 or more home runs since the 2024 season — lowest in MLB.

The Brewers are batting .399 on the first pitch of at-bats this season — best in MLB.

Brewers hitters have an OBP of .341 (5,924 PA’s) this season — best in MLB.

Brewers hitters have an OBP of .347 (4,125 PA’s) against RHP this season — best in MLB.

Brewers hitters have come to the plate with runners in scoring position in 1,769 of their 5,924 plate appearances (30%) this season — highest in MLB.

Pirates hitters have an OBP of .347 (2,849 PA’s) at home this season — 3rd best in MLB.

Pirates hitters have an OBP of .338 (4,037 PA’s) against RHP this season — 3rd best in MLB.

Pirates hitters are slugging just .250 with two-strikes this season — tied for 3rd lowest in MLB.

Pirates hitters have 121 extra-base hits out of 481 total hits (just 25%) with two-strikes this season — tied for lowest in MLB.

The Brewers have won 60% of home games in which their opponents scored first this season — highest in MLB.

The Brewers have won 49% of games in which their opponents scored first this season — highest in MLB.

Brewers pitchers have a strikeout rate of 28% in the first 5 innings this season — best in MLB.

Brewers pitchers have struck out 27% of left-handed batters they faced this season — best in MLB.

The Pirates have won just 22% of games in which their opponents scored first this season — 3rd lowest in MLB.

Pirates pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

The Pirates pitchers have allowed their opponents to score first in just 44% of their games this season — 2nd lowest in MLB.

The Pirates have won just 27% of home games in which their opponents scored first this season — tied for 2nd lowest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.