• The Cubs are -150 favorites vs the Cardinals
• Cardinals vs Cubs Over / Under today: 8 Runs
• Cardinals / Cubs TV Channel: PEAC | NBCX

The St. Louis Cardinals (+125) visit Wrigley Field to take on the Chicago Cubs (-150) on July 5, 2026. First pitch is scheduled for 2:30 pm in Chicago, IL.

This season, the Cardinals are 47-39 against the spread (ATS), while the Cubs are 36-52 ATS.

Cardinals vs Cubs Starting Pitchers Today:

• Cardinals starting pitcher: Matthew Liberatore 4-5, 5.34 ERA
• Cubs starting pitcher: Javier Assad 6-1, 4.53 ERA

Cardinals vs. Cubs Odds, Run Line, Over/Under & Moneyline

Cardinals vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Sunday‘s MLB game with 55.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Nathan Church has hit the Home Runs Over in 3 of his last 5 games (+24.50 Units / 490% ROI)
• Alec Burleson has hit the RBIs Over in 16 of his last 25 games (+15.25 Units / 61% ROI)
• Masyn Winn has hit the Runs Over in 13 of his last 20 games (+11.95 Units / 60% ROI)
• Ivan Herrera has hit the Total Bases Under in 19 of his last 25 games (+10.30 Units / 26% ROI)
• Masyn Winn has hit the Hits Over in 16 of his last 20 games (+9.40 Units / 24% ROI)

And here are some favorite MLB player prop bets for Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Nico Hoerner has hit the Hits Under in 19 of his last 25 games at home (+16.05 Units / 36% ROI)
• Pete Crow-Armstrong has hit the Home Runs Over in 6 of his last 10 games at home (+14.40 Units / 144% ROI)
• Nico Hoerner has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+13.65 Units / 48% ROI)
• Michael Busch has hit the Runs Under in 20 of his last 25 games at home (+13.60 Units / 37% ROI)
• Alex Bregman has hit the Walks Over in 15 of his last 25 games (+12.65 Units / 50% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Team Total Over in 28 of their last 40 away games (+14.40 Units / 30% ROI)
• The St. Louis Cardinals have covered the Run Line in 27 of their last 40 away games (+12.70 Units / 22% ROI)
• The St. Louis Cardinals have hit the Moneyline in 24 of their last 40 away games (+11.70 Units / 28% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 30 of their last 50 games (+10.30 Units / 19% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 games (+9.75 Units / 28% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 50 games (+11.00 Units / 19% ROI)
• The Chicago Cubs have hit the Team Total Under in 15 of their last 22 games at home (+7.60 Units / 30% ROI)
• The Chicago Cubs have hit the Moneyline in 15 of their last 21 games (+7.45 Units / 26% ROI)
• The Chicago Cubs have hit the Game Total Over in 11 of their last 15 games (+6.60 Units / 39% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 12 of their last 22 games (+6.45 Units / 21% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 50-34 against the Run Line (+6.45 Units / 5.26% ROI).

• 47-39 when betting on the Moneyline for +12.1 Units / 13.11% ROI
• 37-45 when betting on the total runs Over for -12.5 Units / -13.22% ROI
• 45-37 when betting on the total runs Under for +4.15 Units / 4.38% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 36-52 against the Run Line (-16 Units / -15.38% ROI).

• 49-40 when betting on the Moneyline for -1.9 Units / -1.57% ROI
• 48-40 when betting on the total runs Over for +4.55 Units / 4.63% ROI
• 40-48 when betting on the total runs Under for -12.1 Units / -12.38% ROI

Cubs vs Cardinals Home Run Prop Bets Today

Cubs vs Cardinals Total Hits Prop Bets Today

Cubs vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Cubs

The Cardinals are 22-14 (.611) vs top 10 scoring offenses this season Today, they face the Cubs (fifth in runs scored).

The Cardinals are 24-18 (.571) on the road this season — 5th best in MLB; League Avg: .476.

The Cardinals are just 11-18 (.379) when tied entering the 8th inning since the 2025 season — 3rd lowest in MLB; League Avg: .500.

The Cardinals are 166-11 (.938) when leading entering the 8th inning since the 2024 season — tied for 4th best in MLB; League Avg: .904.

Cubs Keys to the Game vs. the Cardinals

The Cubs are 4-38 (.095) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .055.

The Cubs are 20-1 (.952) when they’ve had 5 or more XBH this season — 2nd best in MLB; League Avg: .786.

The Cubs are 26-2 (.929) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .753.

The Cubs are 37-3 (.925) when leading entering the 7th inning this season — 5th best in MLB; League Avg: .861.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 17% of their PA’s against LHP this season — 2nd best in MLB.

Cardinals hitters are slugging just .374 at home this season — 5th lowest in MLB.

The Cardinals have a winning percentage of 57% on the road this season — 5th best in MLB.

The Cardinals are batting .181 with two-strikes this season — 4th best in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have an OBP of .338 (3,518 PA’s) this season — tied for 3rd best in MLB.

Cubs hitters have an OBP of .333 (2,542 PA’s) against RHP this season — tied for 5th best in MLB.

Cubs hitters have an OBP of .351 (976 PA’s) against LHP this season — best in MLB.

The Cubs have scored first in just 23% of their games against division opponents this season — lowest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a groundball rate of 46% against Cardinals pitchers this season — highest in MLB.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — tied for lowest in MLB.

Cardinals pitchers have a strikeout rate of just 38% with two-strikes this season — 4th lowest in MLB.

The Cardinals pitchers have allowed their opponents to score first in just 31% of their games on the road this season — 2nd lowest in MLB.

Cubs Pitching Stats & Trends

Opponents have a groundball batting average of just .201 against Cubs pitchers with runners on base this season — best in MLB.

Cubs pitchers have picked-off 15 runners from first base this season — most in MLB.

The Cubs pitchers have allowed division opponents to score first in 77% of their games this season — highest in MLB.

Cubs pitchers have allowed 136 home runs this season — tied for most in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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