• The Cardinals are -115 favorites vs the Reds
• Cardinals vs Reds Over / Under today: 9 Runs
• Cardinals / Reds TV Channel: CATV | RDTV

The St. Louis Cardinals (-115) visit Great American Ball Park to take on the Cincinnati Reds (-105) on August 20, 2026. First pitch is scheduled for 12:40 pm in Cincinnati, OH.

This season, the Cardinals are 65-63 against the spread (ATS), while the Reds are 65-60 ATS.

Cardinals vs Reds Starting Pitchers Today:

• Cardinals starting pitcher: Michael McGreevy 5-9, 3.52 ERA
• Reds starting pitcher: Brady Singer 5-11, 4.65 ERA

Cardinals vs. Reds Odds, Run Line, Over/Under & Moneyline

Cardinals vs Reds Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Thursday‘s MLB game with 54.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Reds and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Thursday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Michael McGreevy has hit the Earned Runs Under in 17 of his last 25 games (+7.40 Units / 25% ROI)
• Michael McGreevy has hit the Hits Allowed Under in 15 of his last 25 games (+4.15 Units / 14% ROI)
• Michael McGreevy has hit the Pitching Outs Over in 7 of his last 10 away games (+3.60 Units / 31% ROI)
• Michael McGreevy has hit the Walks Allowed Over in 4 of his last 5 games (+3.20 Units / 54% ROI)
• Michael McGreevy has hit the Strikeouts Over in 5 of his last 7 games (+3.15 Units / 38% ROI)

And here are some favorite MLB player prop bets for Reds players for Thursday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Best Bets Today:

• Ke’Bryan Hayes has hit the Home Runs Over in 2 of his last 7 games at home (+12.00 Units / 171% ROI)
• Ke’Bryan Hayes has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+11.65 Units / 33% ROI)
• Ke’Bryan Hayes has hit the Total Bases Under in 16 of his last 25 games at home (+9.15 Units / 35% ROI)
• Brady Singer has hit the Hits Allowed Over in 17 of his last 25 games (+8.70 Units / 30% ROI)
• Ke’Bryan Hayes has hit the Runs Under in 20 of his last 25 games at home (+8.20 Units / 14% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 away games (+17.05 Units / 32% ROI)
• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 34 of their last 50 away games (+14.15 Units / 23% ROI)
• The St. Louis Cardinals have hit the Game Total Under in 31 of their last 50 games (+12.35 Units / 23% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 30 games (+9.30 Units / 25% ROI)
• The St. Louis Cardinals have hit the Moneyline in 26 of their last 50 away games (+7.70 Units / 15% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Under in 27 of their last 40 games at home (+12.10 Units / 25% ROI)
• The Cincinnati Reds have hit the Team Total Under in 27 of their last 40 games at home (+12.00 Units / 26% ROI)
• The Cincinnati Reds have hit the Game Total Under in 27 of their last 45 games (+8.30 Units / 17% ROI)
• The Cincinnati Reds have hit the Moneyline in 17 of their last 30 games (+4.25 Units / 12% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 10 of their last 22 games at home (+3.50 Units / 12% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 70-55 against the Run Line (+0.55 Units / 0.31% ROI).

• 65-63 when betting on the Moneyline for +7.8 Units / 5.61% ROI
• 52-70 when betting on the total runs Over for -25.35 Units / -17.97% ROI
• 70-52 when betting on the total runs Under for +12.6 Units / 8.96% ROI

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 65-60 against the Run Line (-11 Units / -6.2% ROI).

• 61-66 when betting on the Moneyline for -4.65 Units / -3.26% ROI
• 66-59 when betting on the total runs Over for +1 Units / 0.71% ROI
• 59-66 when betting on the total runs Under for -13.1 Units / -9.41% ROI

Reds vs Cardinals Home Run Prop Bets Today

Reds vs Cardinals Total Hits Prop Bets Today

Reds vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Reds

The Cardinals are 7-3 (.700) this season — tied for 3rd best in MLB.

The Cardinals are 7-3 (.700) since the 2025 season — tied for 3rd best in MLB.

The Cardinals are 7-3 (.700) since the 2024 season — tied for 3rd best in MLB.

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

Reds Keys to the Game vs. the Cardinals

The Reds are just 0-6 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB.

The Reds are just 0-6 (.000) when trailing entering the 9th inning since the 2025 season — tied for lowest in MLB.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 0-6 (.000) when trailing entering the 9th inning since the 2024 season — tied for lowest in MLB.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — 2nd best in MLB.

Cardinals hitters are slugging just .495 with the pitcher behind in the count this season — lowest in MLB.

Cardinals hitters have an OBP of just .307 (2,411 PA’s) at home this season — tied for 2nd lowest in MLB.

Cardinals hitters have an OPS of just .669 (2,411 PA’s) at home this season — 2nd lowest in MLB.

Reds Hitting Stats & Trends

The Reds are batting just .206 with two outs this season — lowest in MLB.

Reds hitters have struck out in 26% of their PA’s against RHP this season — highest in MLB.

The Reds are batting just .221 with runners on base this season — lowest in MLB.

The Reds are batting just .118 on pitches out of the zone this season — lowest in MLB.

Cardinals Pitching Stats & Trends

The Cardinals pitchers have allowed their opponents to score first in just 32% of their games on the road this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes this season — tied for 5th lowest in MLB.

Cardinals pitchers have an ERA of 2.83 (89.0 IP) this season — 2nd best in MLB.

Opponents have a groundball rate of 45% against Cardinals pitchers this season — 3rd highest in MLB.

Reds Pitching Stats & Trends

Reds pitchers have walked 11% of batters this season — 3rd highest in MLB.

The Reds have allowed 6.50 runs per game (39/6) on the road this season — highest in MLB.

The Reds pitchers have allowed their opponents to score first in 60% of their games this season — 2nd highest in MLB.

The Reds pitchers have allowed their opponents to score first in 66% of their games at home this season — 2nd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Cardinals vs Reds and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.