- The Cardinals are +100 favorites vs the Reds
- Cardinals vs Reds Over / Under today: 9.5 Runs
- Cardinals / Reds TV Channel: CATV | RDTV
The St. Louis Cardinals (+100) visit Great American Ball Park to take on the Cincinnati Reds (-120) on May 24, 2026. First pitch is scheduled for 1:40 pm in Cincinnati, OH.
This season, the Cardinals are 28-21 against the spread (ATS), while the Reds are 30-19 ATS.
Cardinals vs Reds Starting Pitchers Today:
- Cardinals starting pitcher: Matthew Liberatore 2-2, 4.71 ERA
- Reds starting pitcher: Brady Singer 2-4, 6.27 ERA
Cardinals vs. Reds Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cardinals | -1.5 +155 | O 9.5 -102 | +100 |
| Reds | +1.5 -190 | U 9.5 -118 | -120 |
Cardinals vs Reds Prediction for Today’s Game
Based on recent trends the model predicts the Reds will win Sunday‘s MLB game with 51.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Bets Today:
- player high – away
And here are some favorite MLB player prop bets for Reds players for Sunday‘s game, looking at profitable historical betting trends:
Best Reds Player Prop Best Bets Today:
- player high – home
Cardinals Best Bets Today:
- The St. Louis Cardinals have hit the Moneyline in 15 of their last 21 away games (+12.15 Units / 57% ROI)
- The St. Louis Cardinals have hit the Team Total Over in 16 of their last 22 away games (+9.05 Units / 35% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 11 of their last 18 away games (+8.35 Units / 45% ROI)
- The St. Louis Cardinals have covered the Run Line in 14 of their last 18 away games (+7.75 Units / 27% ROI)
- The St. Louis Cardinals have hit the Game Total Under in 10 of their last 14 away games (+6.70 Units / 44% ROI)
Reds Best Bets Today:
- The Cincinnati Reds have hit the Game Total Over in 28 of their last 40 games (+14.55 Units / 33% ROI)
- The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 9 of their last 11 games (+7.20 Units / 56% ROI)
- The Cincinnati Reds have covered the Run Line in 30 of their last 50 games (+5.95 Units / 8% ROI)
- The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 7 of their last 11 games (+5.05 Units / 36% ROI)
- The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 15 of their last 24 games (+5.05 Units / 17% ROI)
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 30-18 against the Run Line (+3.65 Units / 4.96% ROI).
- 28-21 when betting on the Moneyline for +11.5 Units / 22.84% ROI
- 22-24 when betting on the total runs Over for -4.4 Units / -8.19% ROI
- 24-22 when betting on the total runs Under for -0.45 Units / -0.83% ROI
Reds Against the Spread (ATS) Record
Against the spread this season, the Reds are 30-19 against the Run Line (+5.95 Units / 8.11% ROI).
- 26-24 when betting on the Moneyline for +1.5 Units / 2.63% ROI
- 31-18 when betting on the total runs Over for +11 Units / 19.89% ROI
- 18-31 when betting on the total runs Under for -16 Units / -29.25% ROI
Reds vs Cardinals Home Run Prop Bets Today
| Yes | |
|---|---|
| Jordan Walker | +260 |
| Nolan Gorman | +270 |
| Eugenio Suarez | +270 |
| Alec Burleson | +280 |
| JJ Wetherholt | +280 |
Reds vs Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Matt McLain | 0.5 -250 | 0.5 +185 |
| JJ Wetherholt | 0.5 -250 | 0.5 +185 |
| Dane Myers | 0.5 -250 | 0.5 +185 |
| Sal Stewart | 0.5 -235 | 0.5 +175 |
| Elly De La Cruz | 0.5 -225 | 0.5 +165 |
Reds vs Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Jordan Walker | 0.5 -250 | 0.5 +180 |
| Dane Myers | 0.5 -220 | 0.5 +160 |
| JJ Wetherholt | 0.5 -200 | 0.5 +150 |
| Matt McLain | 0.5 -200 | 0.5 +150 |
| Victor Scott II | 0.5 -200 | 0.5 +145 |
Cardinals Keys to the Game vs. the Reds
The Cardinals are 11-4 (.733) vs the bottom 10 runs allowed teams this season Today, they face the Reds (25th runs allowed).
The Cardinals are 3-19 (.136) when trailing entering the 9th inning this season — 2nd best in MLB; League Avg: .053.
The Cardinals are 16-9 (.640) on the road this season — 3rd best in MLB; League Avg: .470.
The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.
Reds Keys to the Game vs. the Cardinals
The Reds are 3-22 (.120) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .053.
The Reds are 22-4 (.846) when allowing 4 or fewer runs this season — 3rd best in MLB; League Avg: .719.
The Reds are just 12-51 (.190) when allowing 10 or more hits since the 2025 season — 5th lowest in MLB; League Avg: .254.
The Reds are just 12-71 (.145) when allowing 5 or more runs since the 2025 season — 5th lowest in MLB; League Avg: .203.
Cardinals Hitting Stats & Trends
Cardinals hitters have struck out in just 18% of their PA’s against LHP this season — 3rd best in MLB.
Cardinals hitters have 31 extra-base hits out of 111 total hits (just 28%) against LHP this season — 4th lowest in MLB.
The Cardinals are batting just .212 with two outs this season — tied for 5th lowest in MLB.
Cardinals hitters have put 40% of their swings in play against LHP this season — 3rd highest in MLB.
Reds Hitting Stats & Trends
The Reds are batting just .215 with runners on base this season — lowest in MLB.
Reds hitters have chased 24% of pitches out of the zone with runners in scoring position this season — lowest in MLB.
The Reds are batting just .193 with two outs this season — lowest in MLB.
The Reds are batting just .122 on pitches out of the zone this season — 2nd lowest in MLB.
Cardinals Pitching Stats & Trends
Cardinals pitchers have a strikeout rate of just 37% with two-strikes this season — lowest in MLB.
Cardinals pitchers have a strikeout rate of just 16% with runners in scoring position this season — lowest in MLB.
Cardinals pitchers have struck out just 18% of left-handed batters they faced this season — tied for lowest in MLB.
Cardinals pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.
Reds Pitching Stats & Trends
Reds pitchers have walked 12% of batters this season — 2nd highest in MLB.
Reds pitchers have a strike rate of just 61% this season — lowest in MLB.
Reds pitchers have a strikeout rate of just 20% this season — 4th lowest in MLB.
Reds pitchers have a first-pitch strike rate of just 57% this season — lowest in MLB.
More MLB Reading:
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