• The Tigers are -170 favorites vs the Cardinals
• Cardinals vs Tigers Over / Under today: 7.5 Runs
• Cardinals / Tigers TV Channel: CATV | DSN | ESUN

The St. Louis Cardinals (+140) visit Comerica Park to take on the Detroit Tigers (-170) on April 4, 2026. First pitch is scheduled for 1:10 pm in Detroit, MI.

This season, the Cardinals are 4-3 against the spread (ATS), while the Tigers are 3-4 ATS.

Cardinals vs Tigers Starting Pitchers Today:

• Cardinals starting pitcher: Dustin May 0-1, 13.51 ERA
• Tigers starting pitcher: Jack Flaherty 0-1, 4.16 ERA

Cardinals vs. Tigers Odds, Run Line, Over/Under & Moneyline

Cardinals vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Saturday‘s MLB game with 55.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Tigers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Saturday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Ivan Herrera has hit the Home Runs Over in 3 of his last 9 away games (+16.10 Units / 179% ROI)
• Thomas Saggese has hit the Total Bases Over in 15 of his last 20 games (+10.55 Units / 35% ROI)
• Ivan Herrera has hit the Runs Under in his last 10 games (+10.00 Units / 65% ROI)
• Thomas Saggese has hit the Hits Over in 16 of his last 20 games (+9.45 Units / 27% ROI)
• Ivan Herrera has hit the Singles Over in 18 of his last 25 away games (+8.90 Units / 27% ROI)

And here are some favorite MLB player prop bets for Tigers players for Saturday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

• Spencer Torkelson has hit the Walks Under in 17 of his last 20 games at home (+11.65 Units / 30% ROI)
• Dillon Dingler has hit the Home Runs Over in 2 of his last 5 games (+9.50 Units / 190% ROI)
• Kerry Carpenter has hit the RBIs Under in 13 of his last 15 games at home (+8.15 Units / 24% ROI)
• Dillon Dingler has hit the Hits Over in his last 8 games (+8.00 Units / 58% ROI)
• Spencer Torkelson has hit the Runs Under in 16 of his last 20 games (+7.85 Units / 21% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Team Total Under in 46 of their last 77 games (+10.70 Units / 12% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 64 of their last 113 games (+9.25 Units / 7% ROI)
• The St. Louis Cardinals have hit the Game Total Over in 21 of their last 36 away games (+6.65 Units / 17% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 9 of their last 19 games (+1.30 Units / 6% ROI)
• The St. Louis Cardinals have covered the Run Line in 36 of their last 67 away games (+0.85 Units / 1% ROI)

Tigers Best Bets Today:

• The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 52 of their last 83 games at home (+20.33 Units / 21% ROI)
• The Detroit Tigers have hit the Game Total Over in 34 of their last 51 games at home (+17.55 Units / 31% ROI)
• The Detroit Tigers have hit the Team Total Over in 30 of their last 48 games at home (+10.70 Units / 20% ROI)
• The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 42 of their last 83 games at home (+2.90 Units / 2% ROI)
• The Detroit Tigers have covered the 1st Five Innings (F5) Run Line in 45 of their last 83 games at home (+1.05 Units / 1% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 4-3 against the Run Line (-0.35 Units / -3.45% ROI).

• 4-3 when betting on the Moneyline for +1.85 Units / 26.24% ROI
• 3-4 when betting on the total runs Over for -1.4 Units / -18.54% ROI
• 4-3 when betting on the total runs Under for +0.55 Units / 7.01% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 3-4 against the Run Line (-0.85 Units / -10.24% ROI).

• 3-4 when betting on the Moneyline for -1.55 Units / -17.71% ROI
• 3-4 when betting on the total runs Over for -1.4 Units / -18.3% ROI
• 4-3 when betting on the total runs Under for +0.65 Units / 8.39% ROI

Cardinals Keys to the Game vs. the Tigers

The Cardinals were just 7-11 (.389) when tied entering the 8th inning in the 2025 season — tied for 5th lowest in MLB; League Avg: .500.

The Cardinals are 28-17 (.622) when tied entering the 7th inning since the 2024 season — 3rd best in MLB; League Avg: .499.

The Cardinals are 130-8 (.942) when leading entering the 8th inning since the 2024 season — 4th best in MLB; League Avg: .904.

The Cardinals were 18-9 (.667) when tied entering the 7th inning in the 2024 season — tied for 3rd best in MLB; League Avg: .498.

Tigers Keys to the Game vs. the Cardinals

The Tigers were 78-1 (.987) when leading entering the 9th inning in the 2025 season — 2nd best in MLB; League Avg: .956.

The Tigers were 74-19 (.796) when they allowed 4 or fewer runs in the 2025 season — best in MLB; League Avg: .714.

The Tigers were 47-9 (.839) when they had 10 or more hits in the 2025 season — 3rd best in MLB; League Avg: .743.

The Tigers were just 4-56 (.067) when trailing entering the 7th inning in the 2025 season — 2nd lowest in MLB; League Avg: .124.

Cardinals Hitting Stats & Trends

Cardinals hitters have an OPS of just .935 (1,214 PA’s) with the pitcher behind in the count since the 2025 season — 2nd lowest in MLB.

Cardinals hitters have an OBP of just .254 (183 PA’s) against RHP this season — 2nd lowest in MLB.

Cardinals hitters are slugging .408 against LHP this season — 3rd best in MLB.

Cardinals hitters slugged just .380 against RHP in the 2025 season — tied for 3rd lowest in MLB.

Tigers Hitting Stats & Trends

Tigers hitters have not drawn a walk in 23 PA’s against LHP this season — lowest in MLB.

Tigers hitters do not have an extra-base hit out of 6 total hits against LHP this season — tied for lowest in MLB.

Tigers hitters are slugging just .210 with bases empty this season — lowest in MLB.

Tigers hitters have an OPS of just .233 (62 PA’s) when leading off an inning this season — lowest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 19% against Cardinals pitchers this season — lowest in MLB.

Cardinals pitchers have a strikeout rate of just 13% this season — lowest in MLB.

Opponents had a miss rate of just 23% against Cardinals pitchers in the 2025 season — 2nd lowest in MLB.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB.

Tigers Pitching Stats & Trends

Tigers pitchers walked 6% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd best in MLB.

Tigers pitchers have walked 6% of batters when facing the leadoff batter in the inning since the 2025 season — best in MLB.

Tigers pitchers have walked 3% of batters when facing the leadoff batter in the inning this season — 3rd best in MLB.

Opponents have a miss rate of just 24% against Tigers pitchers this season — 5th lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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