• The Twins are -140 favorites vs the Cardinals
• Cardinals vs Twins Over / Under today: 8.5 Runs
• Cardinals / Twins TV Channel: TWTV | CATV | KMOV

The St. Louis Cardinals (+115) visit Target Field to take on the Minnesota Twins (-140) on June 12, 2026. First pitch is scheduled for 8:10 pm in Minneapolis, MN.

This season, the Cardinals are against the spread (ATS), while the Twins are ATS.

Cardinals vs Twins Starting Pitchers Today:

• Cardinals starting pitcher: Kyle Leahy 5-3, 4.43 ERA
• Twins starting pitcher: Joe Ryan 4-3, 3.07 ERA

Cardinals vs. Twins Odds, Run Line, Over/Under & Moneyline

Cardinals vs Twins Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Friday‘s MLB game with 55.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Cardinals vs Twins and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today:

• Alec Burleson has hit the Home Runs Over in 4 of his last 6 games (+15.60 Units / 260% ROI)
• Alec Burleson has hit the Hits Over in 19 of his last 25 away games (+12.05 Units / 25% ROI)
• Alec Burleson has hit the Runs Over in 16 of his last 25 away games (+11.30 Units / 45% ROI)
• Nolan Gorman has hit the Total Bases Under in 15 of his last 20 games (+10.25 Units / 42% ROI)
• Alec Burleson has hit the RBIs Over in 7 of his last 10 games (+8.65 Units / 87% ROI)

And here are some favorite MLB player prop bets for Twins players for Friday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Best Bets Today:

• Brooks Lee has hit the Home Runs Over in 2 of his last 6 games (+9.50 Units / 158% ROI)
• Brooks Lee has hit the Runs Under in 16 of his last 20 games at home (+8.70 Units / 23% ROI)
• Brooks Lee has hit the Hits Runs and RBIs Under in 12 of his last 15 games at home (+8.50 Units / 49% ROI)
• Royce Lewis has hit the Total Bases Under in 8 of his last 10 games at home (+7.35 Units / 67% ROI)
• Trevor Larnach has hit the Walks Under in 19 of his last 25 games (+6.95 Units / 13% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 games (+13.65 Units / 22% ROI)
• The St. Louis Cardinals have covered the Run Line in 34 of their last 50 games (+12.55 Units / 17% ROI)
• The St. Louis Cardinals have hit the Moneyline in 29 of their last 50 games (+11.65 Units / 22% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 games (+10.80 Units / 20% ROI)
• The St. Louis Cardinals have hit the Team Total Over in 21 of their last 30 away games (+10.55 Units / 29% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 31 of their last 50 games (+14.45 Units / 26% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 22 of their last 35 games at home (+9.75 Units / 23% ROI)
• The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 23 of their last 35 games at home (+9.45 Units / 22% ROI)
• The Minnesota Twins have hit the Team Total Over in 22 of their last 35 games at home (+8.10 Units / 20% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 24 of their last 40 games (+7.10 Units / 15% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Twins vs Cardinals Home Run Prop Bets Today

Twins vs Cardinals Total Hits Prop Bets Today

Twins vs Cardinals Strikeout Prop Bets Today

Cardinals Keys to the Game vs. the Twins

The Cardinals are 15-4 (.789) when they’ve scored in the first inning this season — tied for 2nd best in MLB; League Avg: .645.

The Cardinals are 13-4 (.765) vs the bottom 10 runs allowed teams this season Today, they face the Twins (25th runs allowed).

The Cardinals are 3-25 (.107) when trailing entering the 9th inning this season — 4th best in MLB; League Avg: .057.

The Cardinals are 12-92 (.115) when trailing entering the 8th inning since the 2025 season — tied for 5th best in MLB; League Avg: .096.

Twins Keys to the Game vs. the Cardinals

The Twins are just 0-32 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .057.

The Twins are just 0-29 (.000) when trailing entering the 8th inning this season — lowest in MLB; League Avg: .110.

The Twins are just 2-7 (.222) when tied entering the 7th inning this season — 3rd lowest in MLB; League Avg: .500.

The Twins are just 7-26 (.212) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

Cardinals Hitting Stats & Trends

Cardinals hitters have struck out in just 17% of their PA’s against LHP this season — 2nd best in MLB.

Cardinals hitters have 93 extra-base hits out of 317 total hits (just 29%) against starting pitchers this season — lowest in MLB.

Cardinals hitters have put 40% of their swings in play against LHP this season — 2nd highest in MLB.

Cardinals hitters have a swing rate of 61% with two-strikes this season — 5th highest in MLB.

Twins Hitting Stats & Trends

The Twins are batting just .279 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters are slugging just .348 against LHP this season — 4th lowest in MLB.

Twins hitters have an OPS of just .640 (819 PA’s) in innings 7-9 this season — 3rd lowest in MLB.

Twins hitters have chased 27% of pitches out of the zone against LHP this season — tied for 3rd lowest in MLB.

Cardinals Pitching Stats & Trends

Opponents have a miss rate of just 23% against Cardinals pitchers this season — 3rd lowest in MLB.

Opponents have a groundball rate of 46% against Cardinals pitchers this season — tied for 2nd highest in MLB.

Cardinals pitchers have a strikeout rate of just 19% with runners in scoring position this season — 3rd lowest in MLB.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes this season — 4th lowest in MLB.

Twins Pitching Stats & Trends

Twins pitchers have an ERA of 5.82 (289.1 IP) on the road this season — highest in MLB.

Opponents have a groundball rate of just 39% against Twins pitchers this season — lowest in MLB.

Opponents have a miss rate of just 23% against Twins pitchers this season — 4th lowest in MLB.

Opponents have a groundball batting average of .277 against Twins pitchers this season — 2nd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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