• The Diamondbacks are +100 favorites vs the Brewers
• Diamondbacks vs Brewers Over / Under today: 8.5 Runs
• Diamondbacks / Brewers TV Channel: DBTV | BRTV

The Arizona Diamondbacks (+100) visit American Family Field to take on the Milwaukee Brewers (-120) on April 29, 2026. First pitch is scheduled for 7:40 pm in Milwaukee, WI.

This season, the Diamondbacks are 15-13 against the spread (ATS), while the Brewers are 17-11 ATS.

Diamondbacks vs Brewers Starting Pitchers Today:

• Diamondbacks starting pitcher: Eduardo Rodriguez 2-0, 2.90 ERA
• Brewers starting pitcher: Brandon Sproat 0-1, 6.45 ERA

Diamondbacks vs. Brewers Odds, Run Line, Over/Under & Moneyline

Diamondbacks vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Wednesday‘s MLB game with 53.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Diamondbacks vs Brewers and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Wednesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Bets Today:

• Ildemaro Vargas has hit the Home Runs Over in 3 of his last 6 games (+21.60 Units / 360% ROI)
• Ildemaro Vargas has hit the Hits Over in 18 of his last 20 games (+16.25 Units / 44% ROI)
• Alek Thomas has hit the Singles Under in 20 of his last 25 games (+13.10 Units / 34% ROI)
• Ildemaro Vargas has hit the Runs Over in 11 of his last 15 games (+11.70 Units / 74% ROI)
• Ketel Marte has hit the Walks Under in 16 of his last 20 games (+9.95 Units / 34% ROI)

And here are some favorite MLB player prop bets for Brewers players for Wednesday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Best Bets Today:

• Gary Sanchez has hit the Home Runs Over in 4 of his last 10 games at home (+12.40 Units / 124% ROI)
• William Contreras has hit the Hits Runs and RBIs Over in 18 of his last 25 games (+9.75 Units / 32% ROI)
• Gary Sanchez has hit the Walks Over in 9 of his last 15 games (+9.55 Units / 64% ROI)
• Brice Turang has hit the Hits Under in 12 of his last 20 games (+9.00 Units / 35% ROI)
• William Contreras has hit the Total Bases Over in 15 of his last 25 games (+8.65 Units / 32% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Over in 18 of their last 22 away games (+14.25 Units / 55% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 32 of their last 50 games (+13.40 Units / 23% ROI)
• The Arizona Diamondbacks have hit the Game Total Over in 29 of their last 50 games (+9.25 Units / 17% ROI)
• The Arizona Diamondbacks have covered the Run Line in 14 of their last 20 games (+6.45 Units / 22% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 15 of their last 25 games (+6.15 Units / 22% ROI)

Brewers Best Bets Today:

• The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 games at home (+11.20 Units / 19% ROI)
• The Milwaukee Brewers have covered the Run Line in 18 of their last 30 games at home (+9.90 Units / 29% ROI)
• The Milwaukee Brewers have hit the Team Total Over in 28 of their last 45 games at home (+8.10 Units / 15% ROI)
• The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 games at home (+6.25 Units / 8% ROI)
• The Milwaukee Brewers have hit the Game Total Over in 28 of their last 50 games at home (+5.75 Units / 10% ROI)

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 19-9 against the Run Line (+7.35 Units / 18.49% ROI).

• 15-13 when betting on the Moneyline for +3.15 Units / 10.08% ROI
• 17-10 when betting on the total runs Over for +6.1 Units / 19.68% ROI
• 10-17 when betting on the total runs Under for -8.4 Units / -27.45% ROI

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 17-11 against the Run Line (+8.35 Units / 24.85% ROI).

• 15-13 when betting on the Moneyline for -2.35 Units / -6.37% ROI
• 16-12 when betting on the total runs Over for +2.6 Units / 8.33% ROI
• 12-16 when betting on the total runs Under for -5.35 Units / -17.57% ROI

Brewers vs Diamondbacks Home Run Prop Bets Today

Brewers vs Diamondbacks Total Hits Prop Bets Today

Brewers vs Diamondbacks Strikeout Prop Bets Today

Diamondbacks Keys to the Game vs. the Brewers

The Diamondbacks are just 70-21 (.769) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .872.

The Diamondbacks are just 78-15 (.839) when leading entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .907.

The Diamondbacks are 4-6 (.400) when trailing entering the 7th inning this season — best in MLB; League Avg: .145.

The Diamondbacks are just 0-10 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .053.

Brewers Keys to the Game vs. the Diamondbacks

The Brewers are just 2-11 (.154) when scoring 4 or fewer runs this season — 3rd lowest in MLB; League Avg: .273.

The Brewers are 84-9 (.903) when scoring 5 or more runs since the 2025 season — 2nd best in MLB; League Avg: .794.

The Brewers are 2-7 (.222) when trailing entering the 8th inning this season — tied for 4th best in MLB; League Avg: .106.

The Brewers are 24-2 (.923) when they’ve had 5 or more XBH since the 2025 season — best in MLB; League Avg: .796.

Diamondbacks Hitting Stats & Trends

Diamondbacks hitters have an OPS of .828 (292 PA’s) against LHP this season — 3rd best in MLB.

The Diamondbacks are batting .392 in lefty-lefty matchups this season — best in MLB.

Diamondbacks hitters are slugging .477 against LHP this season — best in MLB.

The Diamondbacks are batting .298 against LHP this season — best in MLB.

Brewers Hitting Stats & Trends

Brewers hitters have an OBP of .339 (3,707 PA’s) on the road since the 2025 season — best in MLB.

Brewers hitters have a swing rate of just 45% against RHP since the 2025 season — lowest in MLB.

Brewers hitters have 186 extra-base hits out of 694 total hits (just 27%) versus relief pitchers since the 2025 season — lowest in MLB.

Brewers hitters have chased just 19% pitches with the pitcher behind in the count since the 2025 season — lowest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have a strikeout rate of just 19% this season — tied for 2nd lowest in MLB.

Diamondbacks pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — tied for 2nd best in MLB.

Diamondbacks pitchers have a strikeout rate of just 19% with runners in scoring position this season — 2nd lowest in MLB.

Opponents have a miss rate of just 24% against Diamondbacks pitchers since the 2025 season — tied for 4th lowest in MLB.

Brewers Pitching Stats & Trends

Brewers pitchers have walked 9% of batters when facing the leadoff batter in the inning since the 2025 season — tied for 5th highest in MLB.

Brewers pitchers have a strikeout rate of 44% with two-strikes since the 2025 season — tied for 4th best in MLB.

Brewers pitchers have a strikeout rate of 25% this season — 3rd best in MLB.

Opponents have a miss rate of 27% against Brewers pitchers this season — tied for 4th best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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