• The Diamondbacks are -115 favorites vs the Giants
• Diamondbacks vs Giants Over / Under today: 8 Runs
• Diamondbacks / Giants TV Channel: NSBA | DBTV

The Arizona Diamondbacks (-115) visit Oracle Park to take on the San Francisco Giants (-105) on May 26, 2026. First pitch is scheduled for 9:45 pm in San Francisco, CA.

This season, the Diamondbacks are against the spread (ATS), while the Giants are ATS.

Diamondbacks vs Giants Starting Pitchers Today:

• Diamondbacks starting pitcher: Eduardo Rodriguez 4-1, 2.25 ERA
• Giants starting pitcher: Tyler Mahle 1-6, 6.14 ERA

Diamondbacks vs. Giants Odds, Run Line, Over/Under & Moneyline

Diamondbacks vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Diamondbacks vs Giants and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Diamondbacks players for Tuesday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Bets Today:

• Gabriel Moreno has hit the Home Runs Over in 2 of his last 6 games (+15.00 Units / 250% ROI)
• Adrian Del Castillo has hit the Runs Under in his last 15 games (+15.00 Units / 51% ROI)
• Ketel Marte has hit the Total Bases Over in 13 of his last 15 games (+11.90 Units / 72% ROI)
• Geraldo Perdomo has hit the Hits Under in 15 of his last 25 games (+10.75 Units / 37% ROI)
• Adrian Del Castillo has hit the Singles Under in 19 of his last 25 games (+8.20 Units / 20% ROI)

And here are some favorite MLB player prop bets for Giants players for Tuesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

• Casey Schmitt has hit the Home Runs Over in 5 of his last 10 games at home (+25.00 Units / 250% ROI)
• Harrison Bader has hit the Hits Runs and RBIs Under in 16 of his last 20 games at home (+11.15 Units / 40% ROI)
• Rafael Devers has hit the Hits Over in 20 of his last 25 games (+10.75 Units / 24% ROI)
• Rafael Devers has hit the Walks Under in 16 of his last 20 games (+9.70 Units / 28% ROI)
• Rafael Devers has hit the Total Bases Over in 17 of his last 25 games (+9.60 Units / 29% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the Team Total Over in 33 of their last 50 away games (+14.15 Units / 24% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 30 games (+11.75 Units / 34% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 26 of their last 50 games (+7.05 Units / 11% ROI)
• The Arizona Diamondbacks have hit the Game Total Over in 23 of their last 40 away games (+6.55 Units / 15% ROI)
• The Arizona Diamondbacks have covered the Run Line in 30 of their last 50 games (+6.30 Units / 9% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the Team Total Over in 29 of their last 45 games at home (+10.70 Units / 20% ROI)
• The San Francisco Giants have hit the Game Total Over in 23 of their last 40 games at home (+6.40 Units / 14% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 8 games (+6.20 Units / 60% ROI)
• The San Francisco Giants have hit the Moneyline in 11 of their last 17 games at home (+6.15 Units / 33% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 6 of their last 12 games (+2.35 Units / 19% ROI)

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Giants vs Diamondbacks Home Run Prop Bets Today

Giants vs Diamondbacks Total Hits Prop Bets Today

Giants vs Diamondbacks Strikeout Prop Bets Today

Diamondbacks Keys to the Game vs. the Giants

The Diamondbacks are 5-15 (.250) when trailing entering the 7th inning this season — 2nd best in MLB; League Avg: .138.

The Diamondbacks are 16-6 (.727) vs bottom 10 scoring offenses this season Today, they face the Giants (30th in runs scored).

The Diamondbacks are just 83-22 (.790) when leading entering the 7th inning since the 2025 season — 3rd lowest in MLB; League Avg: .872.

The Diamondbacks are just 91-16 (.850) when leading entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .906.

Giants Keys to the Game vs. the Diamondbacks

The Giants are just 16-5 (.762) when leading entering the 7th inning this season — tied for 2nd lowest in MLB; League Avg: .862.

The Giants are just 5-30 (.143) when scoring 4 or fewer runs this season — lowest in MLB; League Avg: .283.

The Giants are 6-2 (.750) when tied entering the 7th inning this season — 3rd best in MLB; League Avg: .500.

The Giants are just 0-25 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .138.

Diamondbacks Hitting Stats & Trends

The Diamondbacks are batting .282 against LHP this season — best in MLB.

Diamondbacks hitters have an OPS of .792 (572 PA’s) against LHP this season — best in MLB.

Diamondbacks hitters have struck out in just 17% of their PA’s against LHP this season — best in MLB.

The Diamondbacks are batting .358 in lefty-lefty matchups this season — best in MLB.

Giants Hitting Stats & Trends

Giants hitters have drawn walks in 6% of their PA’s against RHP this season — lowest in MLB.

Giants hitters have an OBP of just .292 (1,455 PA’s) against RHP this season — lowest in MLB.

Giants hitters have drawn walks in 6% of their PA’s against LHP this season — 2nd lowest in MLB.

Giants hitters have drawn walks in 7% of their PA’s versus relief pitchers this season — lowest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

Diamondbacks pitchers have struck out just 17% of left-handed batters they faced this season — lowest in MLB.

Diamondbacks pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — 2nd best in MLB.

Diamondbacks pitchers have walked 8% of batters this season — 4th best in MLB.

Giants Pitching Stats & Trends

Giants pitchers have thrown at least two strikes in their first three pitches to 57% of opposing batters this season — lowest in MLB.

Opponents have a groundball rate of 47% against Giants pitchers this season — 2nd highest in MLB.

Giants pitchers have induced opposing hitters to ground into 49 double plays in 401 opportunities (12%) this season — best in MLB.

Giants pitchers have 53 three-pitch strikeouts this season — 2nd fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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