• The Giants are -160 favorites vs the Nationals
• Giants vs Nationals Over / Under today: 8 Runs
• Giants / Nationals TV Channel: NSBA | NATV | WTTG

The San Francisco Giants (-160) visit Nationals Park to take on the Washington Nationals (+135) on April 17, 2026. First pitch is scheduled for 6:45 pm in Washington, D.C., DC.

This season, the Giants are 7-12 against the spread (ATS), while the Nationals are 11-7 ATS.

Giants vs Nationals Starting Pitchers Today:

• Giants starting pitcher: Logan Webb 1-2, 5.25 ERA
• Nationals starting pitcher: Zack Littell 0-1, 4.20 ERA

Giants vs. Nationals Odds, Run Line, Over/Under & Moneyline

Giants vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Friday‘s MLB game with 59.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Giants players for Friday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

• Rafael Devers has hit the RBIs Under in his last 10 away games (+10.00 Units / 48% ROI)
• Matt Chapman has hit the Walks Under in 13 of his last 15 games (+10.00 Units / 37% ROI)
• Luis Arraez has hit the Runs Under in 16 of his last 20 away games (+9.55 Units / 30% ROI)
• Drew Gilbert has hit the Singles Under in 19 of his last 25 games (+8.75 Units / 19% ROI)
• Logan Webb has hit the Pitching Outs Under in 15 of his last 20 games (+8.55 Units / 31% ROI)

And here are some favorite MLB player prop bets for Nationals players for Friday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

• CJ Abrams has hit the Home Runs Over in 4 of his last 9 games at home (+19.70 Units / 219% ROI)
• Daylen Lile has hit the Hits Over in 19 of his last 25 games (+12.40 Units / 27% ROI)
• Daylen Lile has hit the Singles Over in 19 of his last 25 games (+11.80 Units / 39% ROI)
• CJ Abrams has hit the Total Bases Over in 12 of his last 15 games (+10.10 Units / 51% ROI)
• Zack Littell has hit the Walks Allowed Under in 9 of his last 10 games at home (+9.50 Units / 53% ROI)

Giants Best Bets Today:

• The San Francisco Giants have hit the Team Total Under in 15 of their last 21 games (+8.65 Units / 37% ROI)
• The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 45 away games (+6.50 Units / 12% ROI)
• The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 29 of their last 50 games (+4.25 Units / 7% ROI)
• The San Francisco Giants have covered the Run Line in 15 of their last 25 away games (+3.80 Units / 11% ROI)
• The San Francisco Giants have hit the Game Total Over in 20 of their last 40 away games (+3.30 Units / 8% ROI)

Nationals Best Bets Today:

• The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 30 games (+11.45 Units / 31% ROI)
• The Washington Nationals have hit the Team Total Over in 29 of their last 45 games (+10.40 Units / 20% ROI)
• The Washington Nationals have hit the Moneyline in 22 of their last 45 games (+9.30 Units / 20% ROI)
• The Washington Nationals have hit the Game Total Over in 29 of their last 50 games at home (+9.05 Units / 16% ROI)
• The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 25 of their last 45 games (+3.75 Units / 7% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 6-12 against the Run Line (-11.1 Units / -39.86% ROI).

• 7-12 when betting on the Moneyline for -5.3 Units / -26.3% ROI
• 8-8 when betting on the total runs Over for -0.75 Units / -3.57% ROI
• 8-8 when betting on the total runs Under for -0.75 Units / -3.61% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 11-7 against the Run Line (+2.7 Units / 11.2% ROI).

• 9-10 when betting on the Moneyline for +4.3 Units / 22.4% ROI
• 13-6 when betting on the total runs Over for +6.45 Units / 30.79% ROI
• 6-13 when betting on the total runs Under for -8.3 Units / -39.71% ROI

Nationals vs Giants Home Run Prop Bets Today

Nationals vs Giants Total Hits Prop Bets Today

Nationals vs Giants Strikeout Prop Bets Today

Giants Keys to the Game vs. the Nationals

The Giants were just 65-6 (.915) when leading entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .956.

The Giants are just 72-6 (.923) when leading entering the 9th inning since the 2025 season — 3rd lowest in MLB; League Avg: .956.

The Giants are just 7-12 (.368) when allowing 5 or more extra base hits this season — 2nd lowest in MLB; League Avg: .521.

The Giants are just 0-9 (.000) when allowing 5 or more runs this season — lowest in MLB; League Avg: .240.

Nationals Keys to the Game vs. the Giants

The Nationals are just 1-5 (.167) at home this season — lowest in MLB; League Avg: .565.

The Nationals are just 32-54 (.368) at home since the 2025 season — 2nd lowest in MLB; League Avg: .545.

The Nationals are 7-2 (.778) when tied entering the 8th inning since the 2025 season — best in MLB; League Avg: .500.

The Nationals were just 65-96 (.401) in the 2025 season — 3rd lowest in MLB; League Avg: .500.

Giants Hitting Stats & Trends

The Giants batted just .214 against LHP in the 2025 season — lowest in MLB.

Giants hitters have an OBP of just .285 (1,814 PA’s) against LHP since the 2025 season — lowest in MLB.

Giants hitters had an OPS of just .631 (1,623 PA’s) against LHP in the 2025 season — lowest in MLB.

Giants hitters slugged just .351 against LHP in the 2025 season — 2nd lowest in MLB.

Nationals Hitting Stats & Trends

The Nationals are batting .306 against LHP this season — best in MLB.

Nationals hitters had an OBP of just .286 (1,704 PA’s) against LHP in the 2025 season — 2nd lowest in MLB.

The Nationals won only 40% of their home games in the 2025 season — 2nd lowest in MLB.

Nationals hitters are slugging .464 against LHP this season — 2nd best in MLB.

Giants Pitching Stats & Trends

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB.

Opponents have a groundball rate of 48% against Giants pitchers this season — 2nd highest in MLB.

Opponents had a groundball rate of 46% against Giants pitchers in the 2025 season — 3rd highest in MLB.

Opponents have a groundball rate of 47% against Giants pitchers since the 2024 season — highest in MLB.

Nationals Pitching Stats & Trends

Nationals pitchers have an ERA of 5.91 (169.0 IP) this season — 2nd highest in MLB.

Nationals pitchers have an ERA of 7.85 (55.0 IP) at home this season — highest in MLB.

Nationals pitchers have an ERA of 5.40 (1593.2 IP) since the 2025 season — 2nd highest in MLB.

The Nationals have allowed 8.33 runs per game (50/6) at home this season — highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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