• The Astros are -130 favorites vs the Guardians
• Guardians vs Astros Over / Under today: 8.5 Runs
• Guardians / Astros TV Channel: GDTV | SCHN

The Cleveland Guardians (+105) visit Daikin Park to take on the Houston Astros (-130) on June 19, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the Guardians are 40-35 against the spread (ATS), while the Astros are 36-40 ATS.

Guardians vs Astros Starting Pitchers Today:

• Guardians starting pitcher: Tanner Bibee 2-7, 3.98 ERA
• Astros starting pitcher: Tatsuya Imai 3-3, 6.50 ERA

Guardians vs. Astros Odds, Run Line, Over/Under & Moneyline

Guardians vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Friday‘s MLB game with 51.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Travis Bazzana has hit the Home Runs Over in 3 of his last 10 away games (+17.00 Units / 170% ROI)
• Travis Bazzana has hit the Singles Under in 19 of his last 25 games (+11.80 Units / 38% ROI)
• Daniel Schneemann has hit the Total Bases Over in 18 of his last 25 away games (+10.15 Units / 31% ROI)
• Rhys Hoskins has hit the RBIs Under in his last 9 games (+9.00 Units / 38% ROI)
• Rhys Hoskins has hit the Runs Under in 13 of his last 15 away games (+8.95 Units / 31% ROI)

And here are some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Isaac Paredes has hit the Home Runs Over in 4 of his last 8 games at home (+17.70 Units / 221% ROI)
• Isaac Paredes has hit the Singles Under in 18 of his last 20 games (+14.60 Units / 48% ROI)
• Cam Smith has hit the Hits Under in 17 of his last 25 games at home (+12.60 Units / 50% ROI)
• Cam Smith has hit the Total Bases Under in 17 of his last 25 games at home (+11.05 Units / 40% ROI)
• Cam Smith has hit the Hits Runs and RBIs Under in 18 of his last 25 games at home (+9.90 Units / 29% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 30 of their last 50 away games (+16.35 Units / 31% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 away games (+14.05 Units / 23% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 away games (+13.15 Units / 24% ROI)
• The Cleveland Guardians have hit the Game Total Under in 29 of their last 50 away games (+6.90 Units / 12% ROI)
• The Cleveland Guardians have hit the Team Total Under in 16 of their last 25 games (+6.15 Units / 21% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 17 of their last 25 games (+9.30 Units / 34% ROI)
• The Houston Astros have hit the Game Total Over in 27 of their last 45 games at home (+7.90 Units / 16% ROI)
• The Houston Astros have hit the Team Total Over in 16 of their last 25 games (+6.95 Units / 25% ROI)
• The Houston Astros have hit the Moneyline in 24 of their last 45 games (+6.00 Units / 13% ROI)
• The Houston Astros have covered the Run Line in 16 of their last 25 games (+5.30 Units / 14% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 37-37 against the Run Line (-1.65 Units / -1.71% ROI).

• 40-35 when betting on the Moneyline for +4.4 Units / 4.92% ROI
• 36-39 when betting on the total runs Over for -6.55 Units / -7.98% ROI
• 39-36 when betting on the total runs Under for -0.95 Units / -1.14% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 36-40 against the Run Line (-10.9 Units / -10.54% ROI).

• 35-41 when betting on the Moneyline for -7.1 Units / -8.15% ROI
• 40-32 when betting on the total runs Over for +3.85 Units / 4.53% ROI
• 32-40 when betting on the total runs Under for -11.7 Units / -14.23% ROI

Astros vs Guardians Home Run Prop Bets Today

Astros vs Guardians Total Hits Prop Bets Today

Astros vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the Astros

The Guardians are just 1-26 (.037) when trailing entering the 7th inning this season — 3rd lowest in MLB; League Avg: .137.

The Guardians are 12-2 (.857) when they’ve hit 2 or more home runs this season — 2nd best in MLB; League Avg: .707.

The Guardians are 46-7 (.852) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .745.

The Guardians are just 9-85 (.095) when trailing entering the 7th inning since the 2025 season — tied for 4th lowest in MLB; League Avg: .128.

Astros Keys to the Game vs. the Guardians

The Astros are 5-1 (.833) when tied entering the 8th inning this season — tied for best in MLB; League Avg: .500.

The Astros are just 14-20 (.412) after a win this season — 4th lowest in MLB; League Avg: .514.

The Astros are just 2-36 (.053) when trailing entering the 7th inning this season — tied for 4th lowest in MLB; League Avg: .137.

The Astros are 27-2 (.931) when leading entering the 7th inning this season — 5th best in MLB; League Avg: .863.

Guardians Hitting Stats & Trends

The Guardians are batting just .219 on the road this season — 2nd lowest in MLB.

9% of Guardians’ hitters plate appearances have lasted only one pitch (262/2,808 PA’s) this season — 2nd lowest in MLB.

The Guardians are batting just .229 this season — tied for 3rd lowest in MLB.

The Guardians are batting just .209 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Astros Hitting Stats & Trends

Astros hitters have struck out in just 20% of their PA’s against LHP this season — 5th best in MLB.

Astros hitters have drawn walks in 8% of their PA’s against LHP this season — 4th lowest in MLB.

The Astros are batting .252 on the road this season — tied for 4th best in MLB.

Astros hitters have 61 extra-base hits out of 159 total hits (38%) against LHP this season — 4th best in MLB.

Guardians Pitching Stats & Trends

Opponents have a miss rate of 28% against Guardians pitchers this season — 2nd best in MLB.

Guardians pitchers have a strikeout rate of 32% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 4th best in MLB.

Guardians pitchers have an ERA of 2.54 (145.0 IP) against division opponents this season — 2nd best in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 12% of batters this season — 2nd highest in MLB.

Astros pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Opponents have a groundball rate of just 40% against Astros pitchers this season — 3rd lowest in MLB.

Astros pitchers have a first-pitch strike rate of just 58% this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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