Guardians vs Mariners Prediction, Odds & Player Prop Bets Today – MLB, Mar 29

Seattle Mariners' Cal Raleigh reacts after hitting his 60th home run during the eighth inning of a baseball game against the Colorado Rockies, Wednesday, Sept. 24, 2025, in Seattle.
AP Photo/Ryan Sun, File
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  • The Mariners are -150 favorites vs the Guardians
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The Cleveland Guardians (+125) visit T-Mobile Park to take on the Seattle Mariners (-150) on March 29, 2026. First pitch is scheduled for 7:20 pm in Seattle, WA.

This season, the Guardians are 2-1 against the spread (ATS), while the Mariners are 1-2 ATS.

Guardians vs Mariners Starting Pitchers Today:

  • Guardians starting pitcher: Slade Cecconi 0-0, 0.00 ERA
  • Mariners starting pitcher: Emerson Hancock 0-0, 0.00 ERA

Guardians vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -175O 7.5 -105+125
Mariners -1.5 +145U 7.5 -115-150

Guardians vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Sunday‘s MLB game with 55.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Chase DeLauter has hit the Home Runs Over in his last 3 games (+18.00 Units / 600% ROI)
  • Jose Ramirez has hit the RBIs Over in 9 of his last 15 away games (+8.80 Units / 59% ROI)
  • Jose Ramirez has hit the Runs Over in 11 of his last 15 away games (+8.80 Units / 58% ROI)
  • Jose Ramirez has hit the Hits Runs and RBIs Over in 11 of his last 15 away games (+6.95 Units / 39% ROI)
  • Steven Kwan has hit the Total Bases Over in 10 of his last 15 away games (+6.70 Units / 40% ROI)

And here are some favorite MLB player prop bets for Mariners players for Sunday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

  • Luke Raley has hit the Home Runs Over in his last 2 games (+15.50 Units / 775% ROI)
  • Cal Raleigh has hit the RBIs Under in 20 of his last 25 games at home (+11.55 Units / 26% ROI)
  • Leonardo Rivas has hit the Runs Under in his last 10 games (+10.00 Units / 38% ROI)
  • Julio Rodriguez has hit the Total Bases Under in 18 of his last 25 games (+8.50 Units / 24% ROI)
  • Julio Rodriguez has hit the Hits Under in 15 of his last 25 games (+8.50 Units / 23% ROI)
  • The Cleveland Guardians have hit the Moneyline in 49 of their last 77 games (+21.25 Units / 23% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 39 of their last 60 away games (+18.30 Units / 28% ROI)
  • The Cleveland Guardians have covered the Run Line in 38 of their last 57 away games (+17.05 Units / 21% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 away games (+14.05 Units / 23% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 90 of their last 162 games (+9.19 Units / 5% ROI)
  • The Seattle Mariners have hit the Game Total Over in 92 of their last 162 games (+19.65 Units / 11% ROI)
  • The Seattle Mariners have hit the Moneyline in 38 of their last 54 games at home (+16.75 Units / 19% ROI)
  • The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 28 of their last 44 games (+9.65 Units / 18% ROI)
  • The Seattle Mariners have covered the Run Line in 21 of their last 33 games (+9.30 Units / 22% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 25 of their last 44 games (+7.65 Units / 11% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 2-1 against the Run Line (+0.5 Units / 11.11% ROI).

  • 2-1 when betting on the Moneyline for +2.1 Units / 70% ROI
  • 2-1 when betting on the total runs Over for +0.95 Units / 29.23% ROI
  • 1-2 when betting on the total runs Under for -1.2 Units / -35.82% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 1-2 against the Run Line (-0.7 Units / -23.33% ROI).

  • 1-2 when betting on the Moneyline for -2.55 Units / -48.57% ROI
  • 2-1 when betting on the total runs Over for +0.95 Units / 29.23% ROI
  • 1-2 when betting on the total runs Under for -1.2 Units / -35.82% ROI

Mariners vs Guardians Home Run Prop Bets Today

Yes
Cal Raleigh (SEA) +290
Julio Rodriguez (SEA) +400
Chase DeLauter (CLE) +425
Randy Arozarena (SEA) +475
Rhys Hoskins (CLE) +550

Mariners vs Guardians Total Hits Prop Bets Today

Over Under
Steven Kwan (CLE) 0.5 -275 0.5 +195
Julio Rodriguez (SEA) 0.5 -275 0.5 +200
Brendan Donovan (SEA) 0.5 -250 0.5 +185
Chase DeLauter (CLE) 0.5 -210 0.5 +155
Jose Ramirez (CLE) 0.5 -210 0.5 +160

Mariners vs Guardians RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +155 0.5 -210
Julio Rodriguez (SEA) 0.5 +165 0.5 -220
Josh Naylor (SEA) 0.5 +165 0.5 -220
Jose Ramirez (CLE) 0.5 +175 0.5 -235
Kyle Manzardo (CLE) 0.5 +180 0.5 -235

Mariners vs Guardians Strikeout Prop Bets Today

Over Under
Emerson Hancock (SEA) 3.5 -140 3.5 +105
Slade Cecconi (CLE) 4.5 -110 4.5 -115

Guardians Keys to the Game vs. the Mariners

The Guardians were 34-12 (.723) when they scored in the first inning in the 2025 season — 5th best in MLB; League Avg: .636.

The Guardians were 24-2 (.923) when they had 5 or more XBH in the 2025 season — 2nd best in MLB; League Avg: .799.

The Guardians were 33-4 (.868) when they had 10 or more hits in the 2025 season — 2nd best in MLB; League Avg: .743.

The Guardians were 50-8 (.847) when they scored 5 or more runs in the 2025 season — tied for 4th best in MLB; League Avg: .797.

Mariners Keys to the Game vs. the Guardians

The Mariners were 5-59 (.078) when trailing entering the 9th inning in the 2025 season — 5th best in MLB; League Avg: .043.

The Mariners were 12-55 (.179) when trailing entering the 7th inning in the 2025 season — 3rd best in MLB; League Avg: .124.

The Mariners were 70-3 (.959) when leading entering the 8th inning in the 2025 season — best in MLB; League Avg: .909.

The Mariners are 148-4 (.974) when leading entering the 9th inning since the 2024 season — best in MLB; League Avg: .953.

The Guardians batted just .186 in righty-righty matchups in the 2025 season — lowest in MLB.

The Guardians batted just .226 in the 2025 season — 2nd lowest in MLB.

Guardians hitters had an OBP of just .296 (5,944 PA’s) in the 2025 season — 2nd lowest in MLB.

Guardians hitters slugged just .295 in righty-righty matchups in the 2025 season — lowest in MLB.

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

The Mariners are batting just .226 when facing the starting pitcher for the 3rd time in a game since the 2024 season — lowest in MLB.

The Mariners are batting just .221 at home since the 2024 season — lowest in MLB.

The Mariners batted .375 on the first pitch of at-bats in the 2025 season — best in MLB.

Opponents had a chase percentage of just 26% against the Guardians pitchers in the 2025 season — lowest in MLB.

Guardians pitchers had an ERA of 2.54 (471.1 IP) against division opponents in the 2025 season — best in MLB.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Guardians pitchers had an ERA of 3.70 (1442.0 IP) in the 2025 season — 4th best in MLB.

Mariners pitchers have allowed an OBP of just .267 (2,929 PA’s) when facing the leadoff batter in the inning since the 2024 season — best in MLB.

Mariners pitchers have walked 7% of batters since the 2024 season — best in MLB.

Mariners pitchers walked 7% of batters in the 2025 season — 3rd best in MLB.

The Mariners pitchers have allowed division opponents to score first in just 33% of their games since the 2023 season — lowest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.