• The Yankees are -170 favorites vs the Guardians
• Guardians vs Yankees Over / Under today: 8.5 Runs
• Guardians / Yankees TV Channel: GDTV | YES

The Cleveland Guardians (+140) visit Yankee Stadium to take on the New York Yankees (-170) on June 4, 2026. First pitch is scheduled for 1:35 pm in Bronx, NY.

This season, the Guardians are 36-27 against the spread (ATS), while the Yankees are 30-30 ATS.

Guardians vs Yankees Starting Pitchers Today:

• Guardians starting pitcher: Slade Cecconi 3-5, 5.29 ERA
• Yankees starting pitcher: Carlos Rodon 1-2, 3.32 ERA

Guardians vs. Yankees Odds, Run Line, Over/Under & Moneyline

Guardians vs Yankees Prediction for Today’s Game

Based on recent trends the model predicts the Yankees will win Thursday‘s MLB game with 53.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Guardians vs Yankees and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Guardians players for Thursday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

• Travis Bazzana has hit the Home Runs Over in 2 of his last 7 away games (+13.00 Units / 186% ROI)
• Steven Kwan has hit the Total Bases Under in 19 of his last 25 games (+12.30 Units / 33% ROI)
• Steven Kwan has hit the Hits Under in 16 of his last 25 games (+12.10 Units / 38% ROI)
• Jose Ramirez has hit the RBIs Over in 9 of his last 15 games (+10.35 Units / 69% ROI)
• Steven Kwan has hit the Hits Runs and RBIs Under in 17 of his last 25 games (+8.50 Units / 28% ROI)

And here are some favorite MLB player prop bets for Yankees players for Thursday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Best Bets Today:

• Ben Rice has hit the Hits Over in 13 of his last 15 games at home (+10.05 Units / 35% ROI)
• Ben Rice has hit the Walks Under in 18 of his last 25 games (+7.70 Units / 19% ROI)
• Austin Wells has hit the Hits Runs and RBIs Under in 14 of his last 20 games at home (+7.50 Units / 29% ROI)
• Anthony Volpe has hit the Runs Under in 9 of his last 10 games at home (+7.20 Units / 32% ROI)
• Ben Rice has hit the RBIs Under in his last 6 games at home (+6.00 Units / 46% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Moneyline in 29 of their last 45 away games (+19.75 Units / 41% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 31 of their last 45 away games (+16.15 Units / 30% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 24 of their last 45 away games (+15.45 Units / 32% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 13 of their last 19 away games (+6.75 Units / 31% ROI)
• The Cleveland Guardians have covered the Run Line in 27 of their last 45 away games (+6.50 Units / 10% ROI)

Yankees Best Bets Today:

• The New York Yankees have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 50 games (+5.25 Units / 9% ROI)
• The New York Yankees have hit the Game Total Over in their last 5 games (+5.00 Units / 93% ROI)
• The New York Yankees have covered the Run Line in 10 of their last 18 games at home (+4.75 Units / 26% ROI)
• The New York Yankees have hit the Team Total Over in 11 of their last 17 games at home (+4.35 Units / 22% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 games at home (+4.05 Units / 4% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 31-32 against the Run Line (-0.8 Units / -1.02% ROI).

• 36-27 when betting on the Moneyline for +8.8 Units / 11.53% ROI
• 32-31 when betting on the total runs Over for -1.7 Units / -2.48% ROI
• 31-32 when betting on the total runs Under for -4.7 Units / -6.7% ROI

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 30-30 against the Run Line (+5.05 Units / 7.82% ROI).

• 36-25 when betting on the Moneyline for -3.55 Units / -3.67% ROI
• 28-30 when betting on the total runs Over for -5.15 Units / -7.69% ROI
• 30-28 when betting on the total runs Under for -1.05 Units / -1.56% ROI

Yankees vs Guardians Home Run Prop Bets Today

Yankees vs Guardians Total Hits Prop Bets Today

Yankees vs Guardians Strikeout Prop Bets Today

Guardians Keys to the Game vs. the Yankees

The Guardians are 9-4 (.692) when tied entering the 7th inning this season — 5th best in MLB; League Avg: .500.

The Guardians are 10-2 (.833) when they’ve hit 2 or more home runs this season — 4th best in MLB; League Avg: .709.

The Guardians are 19-13 (.594) on the road this season — 5th best in MLB; League Avg: .474.

The Guardians are just 1-21 (.045) when trailing entering the 7th inning this season — 5th lowest in MLB; League Avg: .141.

Yankees Keys to the Game vs. the Guardians

The Yankees are 3-19 (.136) when trailing entering the 9th inning this season — best in MLB; League Avg: .054.

The Yankees are 17-1 (.944) when they’ve had 10 or more hits this season — 2nd best in MLB; League Avg: .754.

The Yankees are 21-2 (.913) when they’ve hit 2 or more home runs this season — 2nd best in MLB; League Avg: .709.

The Yankees are 14-1 (.933) when they’ve had 5 or more XBH this season — 4th best in MLB; League Avg: .788.

Guardians Hitting Stats & Trends

Guardians hitters are slugging just .368 against RHP this season — 3rd lowest in MLB.

The Guardians are batting just .165 on changeups this season — lowest in MLB.

Guardians hitters have struck out in just 20% of their PA’s against RHP this season — 5th best in MLB.

Guardians hitters have chased 22% of pitches out of the zone in righty-righty matchups this season — lowest in MLB.

Yankees Hitting Stats & Trends

Yankees hitters are slugging .468 at home this season — best in MLB.

Yankees hitters have drawn walks in 15% of their PA’s when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Yankees hitters are slugging .706 on the first pitch of at-bats this season — best in MLB.

Yankees hitters have an OPS of .806 (742 PA’s) against LHP this season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 29% in late innings this season — best in MLB.

Guardians pitchers have a strikeout rate of 34% in close and late situations this season — best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — 2nd best in MLB.

Opponents have a miss rate of 28% against Guardians pitchers this season — 3rd best in MLB.

Yankees Pitching Stats & Trends

Yankees pitchers have a strikeout rate of 24% with runners in scoring position this season — 5th best in MLB.

Opponents have a groundball rate of 47% against Yankees pitchers this season — highest in MLB.

Yankees pitchers have an ERA of 2.97 (288.1 IP) on the road this season — 2nd best in MLB.

Yankees pitchers have allowed a slugging percentage of just .351 this season — 3rd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

Bet now on Guardians vs Yankees and all games with BetMGM

Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.