• The Mariners are -140 favorites vs the Angels
• Mariners vs Angels Over / Under today: 8 Runs
• Mariners / Angels TV Channel: MRTV | ABTV

The Seattle Mariners (-140) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (+115) on September 16, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Mariners are 70-82 against the spread (ATS), while the Angels are 77-73 ATS.

Mariners vs Angels Starting Pitchers Today:

• Mariners starting pitcher: George Kirby 9-11, 4.27 ERA
• Angels starting pitcher: Yusei Kikuchi 1-5, 4.73 ERA

Mariners vs. Angels Odds, Run Line, Over/Under & Moneyline

Mariners vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Wednesday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Mariners players for Wednesday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

• George Kirby has hit the Hits Allowed Over in 21 of his last 25 games (+18.05 Units / 60% ROI)
• Dominic Canzone has hit the Total Bases Over in 20 of his last 25 away games (+17.95 Units / 57% ROI)
• Randy Arozarena has hit the Home Runs Over in 4 of his last 8 away games (+14.90 Units / 186% ROI)
• Dominic Canzone has hit the Hits Over in 21 of his last 25 away games (+14.90 Units / 33% ROI)
• Randy Arozarena has hit the Walks Under in his last 10 away games (+10.00 Units / 57% ROI)

And here are some favorite MLB player prop bets for Angels players for Wednesday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

• Moisés Ballesteros has hit the Home Runs Over in 3 of his last 9 games (+17.10 Units / 190% ROI)
• Wade Meckler has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+12.50 Units / 43% ROI)
• Christian Moore has hit the Runs Under in his last 10 games (+10.00 Units / 44% ROI)
• Wade Meckler has hit the Hits Over in 19 of his last 25 games at home (+9.30 Units / 22% ROI)
• Wade Meckler has hit the Singles Over in 17 of his last 25 games at home (+8.80 Units / 32% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Game Total Over in 33 of their last 50 away games (+16.80 Units / 31% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 games (+9.50 Units / 27% ROI)
• The Seattle Mariners have hit the Team Total Under in 23 of their last 40 away games (+4.60 Units / 10% ROI)
• The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 4 of their last 7 away games (+0.25 Units / 3% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Game Total Under in 33 of their last 50 games (+15.15 Units / 27% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 games at home (+10.45 Units / 18% ROI)
• The Los Angeles Angels have hit the Team Total Under in 25 of their last 40 games at home (+9.25 Units / 20% ROI)
• The Los Angeles Angels have covered the Run Line in 10 of their last 11 games (+8.60 Units / 52% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 games at home (+7.95 Units / 13% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 57-94 against the Run Line (-35.05 Units / -19.76% ROI).

• 70-82 when betting on the Moneyline for -34.2 Units / -16.83% ROI
• 80-64 when betting on the total runs Over for +9.8 Units / 5.84% ROI
• 64-80 when betting on the total runs Under for -23.55 Units / -14.11% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 77-73 against the Run Line (-18 Units / -8.59% ROI).

• 58-93 when betting on the Moneyline for -23.95 Units / -15.01% ROI
• 62-86 when betting on the total runs Over for -32.15 Units / -19.34% ROI
• 86-62 when betting on the total runs Under for +18.3 Units / 11.02% ROI

Mariners Keys to the Game vs. the Angels

The Mariners are just 2-69 (.028) when trailing entering the 8th inning this season — tied for lowest in MLB.

The Mariners are just 25-39 (.391) vs bottom 10 scoring offenses this season Today, they face the Angels (29th in runs scored).

The Mariners are just 12-59 (.169) when allowing 5 or more runs this season — 5th lowest in MLB.

The Mariners are just 2-72 (.027) when trailing entering the 9th inning this season — tied for 3rd lowest in MLB.

Angels Keys to the Game vs. the Mariners

The Angels are just 51-11 (.823) when leading entering the 9th inning this season — lowest in MLB.

The Angels are just 4-16 (.200) when tied entering the 8th inning this season — lowest in MLB.

The Angels are just 5-18 (.217) when tied entering the 7th inning this season — 2nd lowest in MLB.

The Angels are just 56-87 (.392) when allowing 5 or more extra base hits this season — lowest in MLB.

Mariners Hitting Stats & Trends

Mariners hitters are slugging just .477 on the first pitch of at-bats this season — lowest in MLB.

The Mariners are batting just .152 with two-strikes this season — lowest in MLB.

The Mariners are just 29-48 (.377) against the run line (-22.7% ROI) on the road this season — lowest in MLB.

Mariners hitters have an OPS of just .646 (1,885 PA’s) against LHP this season — lowest in MLB.

Angels Hitting Stats & Trends

Angels hitters have struck out in 26% of their PA’s against RHP this season — 2nd highest in MLB.

Angels hitters are slugging just .332 at home this season — lowest in MLB.

Angels hitters are slugging just .368 against RHP this season — lowest in MLB.

Angels hitters have an OPS of just .630 (2,775 PA’s) at home this season — lowest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have a first-pitch strike rate of 66% this season — highest in MLB.

Mariners pitchers have walked 7% of batters this season — 2nd best in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 69% of opposing batters this season — highest in MLB.

Mariners pitchers have walked 7% of batters when facing the leadoff batter in the inning this season — 4th best in MLB.

Angels Pitching Stats & Trends

Angels pitchers have walked 10% of batters this season — tied for highest in MLB.

Angels pitchers have won only 15% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB.

The Angels have won just 20% of games in which their opponents scored first this season — lowest in MLB.

Opponents have a miss rate of 28% against Angels pitchers this season — tied for 2nd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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