• The Mariners are -105 favorites vs the Guardians
• Mariners vs Guardians Over / Under today: 7.5 Runs
• Mariners / Guardians TV Channel: GDTV | WKYC | MRTV

The Seattle Mariners (-105) visit Progressive Field to take on the Cleveland Guardians (-115) on June 26, 2026. First pitch is scheduled for 7:10 pm in Cleveland, OH.

This season, the Mariners are against the spread (ATS), while the Guardians are ATS.

Mariners vs Guardians Starting Pitchers Today:

• Mariners starting pitcher: Luis Castillo 2-6, 5.25 ERA
• Guardians starting pitcher: Joey Cantillo 6-3, 4.09 ERA

Mariners vs. Guardians Odds, Run Line, Over/Under & Moneyline

Mariners vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Friday‘s MLB game with 52.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

• Colt Emerson has hit the Home Runs Over in 3 of his last 10 away games (+13.90 Units / 139% ROI)
• Cal Raleigh has hit the Hits Runs and RBIs Under in 17 of his last 20 games (+13.80 Units / 57% ROI)
• Cal Raleigh has hit the Runs Under in 17 of his last 20 games (+13.20 Units / 51% ROI)
• Cal Raleigh has hit the RBIs Under in 17 of his last 20 games (+11.25 Units / 28% ROI)
• Cal Raleigh has hit the Total Bases Under in 16 of his last 20 games (+11.15 Units / 39% ROI)

And here are some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Steven Kwan has hit the Total Bases Under in 19 of his last 25 games at home (+10.15 Units / 23% ROI)
• Daniel Schneemann has hit the Hits Under in 16 of his last 25 games (+9.45 Units / 37% ROI)
• Travis Bazzana has hit the Home Runs Over in 2 of his last 7 games (+9.30 Units / 133% ROI)
• Daniel Schneemann has hit the Runs Under in 13 of his last 15 games at home (+9.05 Units / 29% ROI)
• Daniel Schneemann has hit the Singles Under in his last 9 games (+9.00 Units / 56% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the Team Total Under in 18 of their last 23 games (+12.45 Units / 47% ROI)
• The Seattle Mariners have hit the Game Total Over in 11 of their last 17 away games (+5.85 Units / 32% ROI)
• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 10 games (+5.75 Units / 48% ROI)
• The Seattle Mariners have covered the Run Line in 11 of their last 23 away games (+2.05 Units / 8% ROI)
• The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 13 of their last 24 away games (+1.20 Units / 4% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Team Total Under in 19 of their last 30 games (+7.20 Units / 21% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 24 of their last 50 games (+6.35 Units / 10% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 9 games at home (+5.15 Units / 47% ROI)
• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 6 of their last 9 games at home (+3.40 Units / 34% ROI)
• The Cleveland Guardians have hit the Game Total Over in 9 of their last 14 games at home (+3.35 Units / 22% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Guardians vs Mariners Home Run Prop Bets Today

Guardians vs Mariners Total Hits Prop Bets Today

Guardians vs Mariners Strikeout Prop Bets Today

Mariners Keys to the Game vs. the Guardians

The Mariners are just 7-19 (.269) vs bottom 10 scoring offenses this season Today, they face the Guardians (28th in runs scored).

The Mariners are just 1-36 (.027) when trailing entering the 9th inning this season — tied for 5th lowest in MLB; League Avg: .059.

The Mariners are just 6-15 (.286) vs the top 10 runs allowed teams this season Today, they face Guardians (eighth in runs allowed).

The Mariners are just 1-32 (.030) when trailing entering the 8th inning this season — 4th lowest in MLB; League Avg: .105.

Guardians Keys to the Game vs. the Mariners

The Guardians are 13-2 (.867) when they’ve hit 2 or more home runs this season — 2nd best in MLB; League Avg: .698.

The Guardians are just 1-30 (.032) when trailing entering the 7th inning this season — 2nd lowest in MLB; League Avg: .142.

The Guardians are 47-7 (.855) when they’ve had 10 or more hits since the 2025 season — 2nd best in MLB; League Avg: .746.

The Guardians are 32-3 (.914) when they’ve had 5 or more XBH since the 2025 season — best in MLB; League Avg: .795.

Mariners Hitting Stats & Trends

The Mariners are batting just .207 against LHP this season — lowest in MLB.

Mariners hitters are slugging just .322 against LHP this season — lowest in MLB.

The Mariners are just 6-20 (.231) against the run line (-44.3% ROI) vs bottom 10 scoring offenses this season Today, they face the Guardians (28th in runs scored).

Mariners hitters have an OPS of just .653 (963 PA’s) in innings 7-9 this season — 2nd lowest in MLB.

Guardians Hitting Stats & Trends

The Guardians are batting just .218 on the road this season — tied for lowest in MLB.

Guardians hitters are slugging just .366 this season — 2nd lowest in MLB.

The Guardians are hitting just .169 against pitchers who have thrown at least 80 pitches in the game this season — lowest in MLB.

Guardians hitters are slugging just .348 against LHP this season — 2nd lowest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have a first-pitch strike rate of 66% this season — highest in MLB.

Mariners pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — tied for best in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 69% of opposing batters this season — highest in MLB.

Mariners pitchers have walked 7% of batters this season — best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 31% in close and late situations this season — best in MLB.

Opponents have a miss rate of 28% against Guardians pitchers this season — 3rd best in MLB.

Guardians pitchers have a strikeout rate of 25% this season — tied for 3rd best in MLB.

Guardians pitchers have 98 three-pitch strikeouts this season — 5th fewest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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