- The Guardians are -180 favorites vs the Nationals
- Nationals vs Guardians Over / Under today: 8 Runs
- Nationals / Guardians TV Channel: GDTV | NATV
The Washington Nationals (+145) visit Progressive Field to take on the Cleveland Guardians (-180) on May 25, 2026. First pitch is scheduled for 6:10 pm in Cleveland, OH.
This season, the Nationals are 27-27 against the spread (ATS), while the Guardians are 29-26 ATS.
Nationals vs Guardians Starting Pitchers Today:
- Nationals starting pitcher: Zack Littell 3-4, 5.83 ERA
- Guardians starting pitcher: Tanner Bibee 0-6, 3.75 ERA
Nationals vs. Guardians Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Nationals | +1.5 -145 | O 8 -105 | +145 |
| Guardians | -1.5 +120 | U 8 -115 | -180 |
Nationals vs Guardians Prediction for Today’s Game
Based on recent trends the model predicts the Guardians will win Monday‘s MLB game with 61.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on Nationals vs Guardians and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for Nationals players for Monday‘s game, looking at profitable historical betting trends:
Best Nationals Player Prop Bets Today:
- Jose Tena has hit the Singles Under in 14 of his last 15 games (+12.40 Units / 59% ROI)
- Luis Garcia has hit the Hits Under in 15 of his last 25 games (+11.16 Units / 36% ROI)
- Jose Tena has hit the Home Runs Over in 2 of his last 9 games (+10.00 Units / 111% ROI)
- Luis Garcia has hit the Runs Under in his last 8 games (+8.00 Units / 60% ROI)
- Jorbit Vivas has hit the Hits Runs and RBIs Over in his last 7 away games (+7.65 Units / 82% ROI)
And here are some favorite MLB player prop bets for Guardians players for Monday‘s game, looking at profitable historical betting trends:
Best Guardians Player Prop Best Bets Today:
- Angel Martinez has hit the Home Runs Over in 4 of his last 5 games at home (+27.90 Units / 558% ROI)
- Steven Kwan has hit the Walks Over in 8 of his last 10 games at home (+12.20 Units / 122% ROI)
- Patrick Bailey has hit the Singles Under in his last 9 games (+9.00 Units / 55% ROI)
- Patrick Bailey has hit the Hits Runs and RBIs Under in 16 of his last 25 games (+8.35 Units / 29% ROI)
- Chase DeLauter has hit the Runs Under in 12 of his last 15 games at home (+8.20 Units / 37% ROI)
Nationals Best Bets Today:
- team high – away
Guardians Best Bets Today:
- team high – home
Nationals Against the Spread (ATS) Record
Against the spread this season, the Nationals are 34-19 against the Run Line (+8.25 Units / 11.13% ROI).
- 27-27 when betting on the Moneyline for +7.85 Units / 14.59% ROI
- 33-18 when betting on the total runs Over for +14.6 Units / 25.02% ROI
- 18-33 when betting on the total runs Under for -19.1 Units / -32.76% ROI
Guardians Against the Spread (ATS) Record
Against the spread this season, the Guardians are 29-26 against the Run Line (+2.65 Units / 3.91% ROI).
- 32-23 when betting on the Moneyline for +8.4 Units / 12.97% ROI
- 26-29 when betting on the total runs Over for -4.4 Units / -7.44% ROI
- 29-26 when betting on the total runs Under for -0.7 Units / -1.17% ROI
Guardians vs Nationals Home Run Prop Bets Today
| Yes | |
|---|---|
| James Wood | +390 |
| Jose Ramirez | +400 |
| Kyle Manzardo | +400 |
| Angel Martinez | +500 |
| Luis Garcia Jr. | +600 |
Guardians vs Nationals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Daylen Lile | 0.5 -200 | 0.5 +145 |
| Kyle Manzardo | 0.5 -190 | 0.5 +140 |
| Steven Kwan | 0.5 -175 | 0.5 +130 |
| Jose Tena | 0.5 -160 | 0.5 +120 |
Guardians vs Nationals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Daniel Schneemann | 0.5 -200 | 0.5 +150 |
| CJ Abrams | 0.5 -190 | 0.5 +140 |
| Zack Littell | 2.5 -160 | 2.5 +120 |
| Daylen Lile | 0.5 -150 | 0.5 +110 |
| Patrick Bailey | 0.5 -140 | 0.5 +105 |
Nationals Keys to the Game vs. the Guardians
The Nationals are just 0-23 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .053.
The Nationals are just 20-6 (.769) when leading entering the 7th inning this season — 3rd lowest in MLB; League Avg: .863.
The Nationals are 21-4 (.840) when allowing 4 or fewer runs this season — 4th best in MLB; League Avg: .717.
The Nationals are 9-4 (.692) when tied entering the 8th inning since the 2025 season — best in MLB; League Avg: .500.
Guardians Keys to the Game vs. the Nationals
The Guardians are 10-1 (.909) when they’ve had 10 or more hits this season — 5th best in MLB; League Avg: .754.
The Guardians are 22-1 (.957) when leading entering the 7th inning this season — 4th best in MLB; League Avg: .863.
The Guardians are 9-4 (.692) when tied entering the 7th inning this season — 5th best in MLB; League Avg: .500.
The Guardians are 9-2 (.818) when they’ve hit 2 or more home runs this season — 5th best in MLB; League Avg: .704.
Nationals Hitting Stats & Trends
The Nationals are batting just .186 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.
The Nationals are batting .264 against LHP this season — 3rd best in MLB.
Nationals hitters have an OBP of .350 (613 PA’s) against LHP this season — tied for best in MLB.
The Nationals have scored 93 runs in late innings this season — most in MLB.
Guardians Hitting Stats & Trends
9% of Guardians’ hitters plate appearances have lasted only one pitch (180/2,063 PA’s) this season — lowest in MLB.
Guardians hitters have struck out in just 19% of their PA’s against LHP this season — 4th best in MLB.
The Guardians are batting just .215 against starting pitchers this season — 2nd lowest in MLB.
Guardians hitters have an OBP of just .255 (145 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.
Nationals Pitching Stats & Trends
Nationals pitchers have a strikeout rate of just 39% with two-strikes this season — 3rd lowest in MLB.
Opponents have a miss rate of just 23% against Nationals pitchers this season — lowest in MLB.
The Nationals have allowed 6.35 runs per game (165/26) at home this season — highest in MLB.
Nationals pitchers have a strikeout rate of just 20% this season — 5th lowest in MLB.
Guardians Pitching Stats & Trends
Guardians pitchers have a strikeout rate of 35% in close and late situations this season — best in MLB.
Guardians pitchers have struck out 28% of left-handed batters they faced this season — best in MLB.
Guardians pitchers have a strikeout rate of 29% in late innings this season — best in MLB.
Guardians pitchers have a strikeout rate of 25% this season — 2nd best in MLB.
More MLB Reading:
Bet now on Nationals vs Guardians and all games with BetMGM
Bet on MLB Odds at BetMGM
Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.
The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.
