Nationals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 16

Pittsburgh Pirates' Jack Suwinski follows through on a single during the fourth inning of a baseball game against the Miami Marlins, Saturday, June 24, 2023, in Miami.
(AP Photo/Lynne Sladky)
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  • The Pirates are -155 favorites vs the Nationals
  • Nationals vs Pirates Over / Under today: 8.5 Runs
  • Nationals / Pirates TV Channel: SNPT | NATV

The Washington Nationals (+130) visit PNC Park to take on the Pittsburgh Pirates (-155) on April 16, 2026. First pitch is scheduled for 12:35 pm in Pittsburgh, PA.

This season, the Nationals are 8-10 against the spread (ATS), while the Pirates are 12-6 ATS.

Nationals vs Pirates Starting Pitchers Today:

  • Nationals starting pitcher: Foster Griffin 2-0, 1.76 ERA
  • Pirates starting pitcher: Braxton Ashcraft 1-1, 2.12 ERA

Nationals vs. Pirates Odds, Run Line, Over/Under & Moneyline

Nationals vs Pirates Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Thursday‘s MLB game with 59.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Nationals players for Thursday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

  • CJ Abrams has hit the Home Runs Over in 3 of his last 7 away games (+19.60 Units / 280% ROI)
  • Daylen Lile has hit the Hits Over in 18 of his last 20 away games (+18.70 Units / 51% ROI)
  • Daylen Lile has hit the Singles Over in 18 of his last 20 away games (+15.65 Units / 66% ROI)
  • CJ Abrams has hit the Total Bases Over in 13 of his last 15 games (+12.40 Units / 63% ROI)
  • CJ Abrams has hit the Hits Runs and RBIs Over in 12 of his last 15 games (+10.10 Units / 61% ROI)

And here are some favorite MLB player prop bets for Pirates players for Thursday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Best Bets Today:

  • Bryan Reynolds has hit the Walks Over in 15 of his last 20 games at home (+18.45 Units / 92% ROI)
  • Bryan Reynolds has hit the Runs Over in 18 of his last 25 games at home (+15.20 Units / 60% ROI)
  • Ryan O’Hearn has hit the Total Bases Over in 19 of his last 25 games (+13.60 Units / 42% ROI)
  • Ryan O’Hearn has hit the Hits Over in 20 of his last 25 games (+13.35 Units / 31% ROI)
  • Oneil Cruz has hit the RBIs Over in 10 of his last 20 games at home (+8.00 Units / 40% ROI)
  • The Washington Nationals have hit the Moneyline in 14 of their last 24 away games (+14.25 Units / 59% ROI)
  • The Washington Nationals have hit the Team Total Over in 29 of their last 45 games (+10.40 Units / 20% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 games (+9.45 Units / 26% ROI)
  • The Washington Nationals have covered the Run Line in 13 of their last 17 away games (+8.70 Units / 44% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in 12 of their last 24 away games (+7.30 Units / 30% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 33 of their last 50 games at home (+14.90 Units / 22% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Moneyline in 28 of their last 50 games at home (+13.25 Units / 20% ROI)
  • The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 33 of their last 50 games at home (+12.75 Units / 21% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 31 of their last 50 games at home (+11.25 Units / 18% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Over in 32 of their last 50 games at home (+11.20 Units / 18% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 10-7 against the Run Line (+1.7 Units / 7.52% ROI).

  • 8-10 when betting on the Moneyline for +2.9 Units / 15.93% ROI
  • 12-6 when betting on the total runs Over for +5.45 Units / 27.46% ROI
  • 6-12 when betting on the total runs Under for -7.2 Units / -36.36% ROI

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 12-6 against the Run Line (+5.45 Units / 22.38% ROI).

  • 11-7 when betting on the Moneyline for +4 Units / 17.82% ROI
  • 10-8 when betting on the total runs Over for +1.15 Units / 5.81% ROI
  • 8-10 when betting on the total runs Under for -3.05 Units / -15.4% ROI

Pirates vs Nationals Home Run Prop Bets Today

Yes
Marcell Ozuna +425
Oneil Cruz +450
Ryan O'Hearn +525
Henry Davis +575
Billy Cook +600

Pirates vs Nationals Total Hits Prop Bets Today

Over Under
Luis Garcia Jr. 0.5 -275 0.5 +190
Nick Yorke 0.5 -250 0.5 +180
Nick Gonzales 0.5 -235 0.5 +175
Daylen Lile 0.5 -235 0.5 +175
Ryan O'Hearn 0.5 -225 0.5 +165

Pirates vs Nationals Strikeout Prop Bets Today

Over Under
Billy Cook 0.5 -210 0.5 +155
Bryan Reynolds 0.5 -185 0.5 +135
Marcell Ozuna 0.5 -175 0.5 +130
Konnor Griffin 0.5 -175 0.5 +130
Jacob Young 0.5 -165 0.5 +125

Nationals Keys to the Game vs. the Pirates

The Nationals were just 64-79 (.444) when allowing 5 or more extra base hits in the 2025 season — 3rd lowest in MLB; League Avg: .535.

The Nationals are 7-2 (.778) when tied entering the 8th inning since the 2025 season — best in MLB; League Avg: .500.

The Nationals were just 11-43 (.200) when their opponents score in the first inning in the 2025 season — lowest in MLB; League Avg: .362.

The Nationals are just 5-3 (.625) when leading entering the 7th inning this season — 2nd lowest in MLB; League Avg: .870.

Pirates Keys to the Game vs. the Nationals

The Pirates are just 7-55 (.113) when allowing 5 or more runs since the 2025 season — 2nd lowest in MLB; League Avg: .206.

The Pirates were just 5-65 (.071) when trailing entering the 7th inning in the 2025 season — 3rd lowest in MLB; League Avg: .124.

The Pirates were just 4-75 (.051) when trailing entering the 8th inning in the 2025 season — tied for 2nd lowest in MLB; League Avg: .090.

The Pirates are just 14-91 (.133) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB; League Avg: .250.

The Nationals are batting .301 against LHP this season — best in MLB.

Nationals hitters are slugging .321 on pitches out of the zone this season — best in MLB.

Nationals hitters struck out in 25% of their PA’s against LHP in the 2025 season — 3rd highest in MLB.

Nationals hitters have struck out in just 19% of their PA’s against RHP this season — 3rd best in MLB.

Pirates hitters slugged just .333 on the road in the 2025 season — 2nd lowest in MLB.

Pirates hitters slugged just .354 against RHP in the 2025 season — lowest in MLB.

Pirates hitters are slugging just .358 against RHP since the 2025 season — 2nd lowest in MLB.

Pirates hitters had an OPS of just .622 (3,034 PA’s) on the road in the 2025 season — 2nd lowest in MLB.

Nationals pitchers have an ERA of 7.85 (55.0 IP) at home this season — highest in MLB.

Nationals pitchers have an ERA of 5.40 (1583.2 IP) since the 2025 season — 2nd highest in MLB.

The Nationals have allowed 8.33 runs per game (50/6) at home this season — highest in MLB.

Nationals pitchers have a strikeout rate of just 15% with runners in scoring position this season — 2nd lowest in MLB.

Pirates pitchers have walked 16% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Pirates pitchers walked 7% of batters when facing the leadoff batter in the inning in the 2025 season — 5th best in MLB.

Pirates pitchers won only 14% of games in which they allowed their opponent to score in three different innings in the 2025 season — 2nd lowest in MLB.

Pirates pitchers have walked 13% of batters when facing the leadoff batter in the inning this month (13 games) — 2nd highest in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.