Nationals vs Tigers Prediction, Odds & Player Prop Bets Today – MLB, Sep 21

(AP Photo/Jeff Chiu)
Odds Boost This Week
  • The Tigers are -155 favorites vs the Nationals
  • Nationals vs Tigers Over / Under today: 8 Runs
  • Nationals / Tigers TV Channel: DSN | NATV

The Washington Nationals (+125) visit Comerica Park to take on the Detroit Tigers (-155) on September 21, 2026. First pitch is scheduled for 6:40 pm in Detroit, MI.

This season, the Nationals are 73-83 against the spread (ATS), while the Tigers are 74-76 ATS.

Nationals vs Tigers Starting Pitchers Today:

  • Nationals starting pitcher: Davidjohn Herz 0-0, 0.00 ERA
  • Tigers starting pitcher: River Ryan 0-0, 0.00 ERA

Nationals vs. Tigers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Nationals+1.5 -160O 8 +100+125
Tigers -1.5 +135U 8 -120-155

Nationals vs Tigers Prediction for Today’s Game

Based on recent trends the model predicts the Tigers will win Monday‘s MLB game with 54.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Nationals players for Monday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

  • Keibert Ruiz has hit the Home Runs Over in 2 of his last 6 away games (+14.00 Units / 233% ROI)
  • Nasim Nuรฑez has hit the Hits Runs and RBIs Under in 16 of his last 20 away games (+11.75 Units / 42% ROI)
  • Abimelec Ortiz has hit the Hits Under in 13 of his last 20 games (+10.50 Units / 52% ROI)
  • Dylan Crews has hit the Runs Under in 20 of his last 25 away games (+10.15 Units / 22% ROI)
  • Abimelec Ortiz has hit the Total Bases Under in 15 of his last 20 games (+9.70 Units / 34% ROI)

And here are some favorite MLB player prop bets for Tigers players for Monday‘s game, looking at profitable historical betting trends:

Best Tigers Player Prop Best Bets Today:

  • Dillon Dingler has hit the Runs Under in 22 of his last 25 games (+16.80 Units / 36% ROI)
  • Dillon Dingler has hit the Hits Runs and RBIs Under in 20 of his last 25 games (+14.65 Units / 48% ROI)
  • Dillon Dingler has hit the Total Bases Under in 20 of his last 25 games at home (+13.25 Units / 36% ROI)
  • Javier Baez has hit the Singles Under in 14 of his last 15 games (+12.50 Units / 59% ROI)
  • Hao-Yu Lee has hit the Home Runs Over in 2 of his last 5 games (+11.90 Units / 238% ROI)
  • The Washington Nationals have hit the Team Total Over in 24 of their last 40 games (+6.95 Units / 15% ROI)
  • The Washington Nationals have hit the Game Total Over in 13 of their last 20 games (+6.35 Units / 29% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 16 of their last 25 away games (+5.35 Units / 17% ROI)
  • The Washington Nationals have hit the Moneyline in 6 of their last 8 games (+4.85 Units / 51% ROI)
  • The Washington Nationals have covered the 1st Five Innings (F5) Run Line in 13 of their last 21 games (+4.05 Units / 17% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Moneyline in 29 of their last 50 games at home (+17.25 Units / 24% ROI)
  • The Detroit Tigers have hit the Game Total Under in 23 of their last 40 games at home (+7.50 Units / 17% ROI)
  • The Detroit Tigers have covered the 1st Five Innings (F5) Run Line in 24 of their last 40 games at home (+7.30 Units / 16% ROI)
  • The Detroit Tigers have covered the Run Line in 12 of their last 18 games (+6.00 Units / 23% ROI)
  • The Detroit Tigers have hit the 1st Five Innings (F5) Team Total Over in 14 of their last 22 games at home (+5.75 Units / 23% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 87-67 against the Run Line (+7.65 Units / 3.66% ROI).

  • 73-83 when betting on the Moneyline for +0.6 Units / 0.36% ROI
  • 82-66 when betting on the total runs Over for +10 Units / 5.82% ROI
  • 66-82 when betting on the total runs Under for -23.75 Units / -13.85% ROI

Tigers Against the Spread (ATS) Record

Against the spread this season, the Tigers are 74-76 against the Run Line (-6.2 Units / -3.11% ROI).

  • 73-83 when betting on the Moneyline for -21.15 Units / -11.01% ROI
  • 68-80 when betting on the total runs Over for -19.7 Units / -11.47% ROI
  • 80-68 when betting on the total runs Under for +5.5 Units / 3.21% ROI

Nationals Keys to the Game vs. the Tigers

The Nationals are just 58-20 (.744) when leading entering the 7th inning this season — lowest in MLB.

The Nationals are just 2-62 (.031) when trailing entering the 8th inning this season — 3rd lowest in MLB.

The Nationals are just 35-26 (.574) when they’ve hit 2 or more home runs this season — 3rd lowest in MLB.

The Nationals are just 1-72 (.014) when trailing entering the 9th inning this season — lowest in MLB.

Tigers Keys to the Game vs. the Nationals

The Tigers are just 63-40 (.612) when allowing 4 or fewer runs this season — 2nd lowest in MLB.

The Tigers are just 4-10 (.286) when tied entering the 8th inning this season — 2nd lowest in MLB.

The Tigers are just 3-11 (.214) when tied entering the 7th inning this season — lowest in MLB.

The Tigers are just 59-18 (.766) when leading entering the 7th inning this season — 2nd lowest in MLB.

Nationals hitters have an OPS of .771 (1,776 PA’s) against LHP this season — 3rd best in MLB.

Nationals hitters have 159 extra-base hits out of 412 total hits (39%) against LHP this season — best in MLB.

Nationals hitters have an OPS of .546 (3,138 PA’s) with two-strikes this season — 3rd best in MLB.

Nationals hitters are slugging .247 on pitches out of the zone this season — 2nd best in MLB.

Tigers hitters have been successful in just 56% of their sacrifice bunt attempts this season — lowest in MLB.

The Tigers are batting just .134 on pitches out of the zone this season — 3rd lowest in MLB.

Tigers hitters have chased 26% of pitches out of the zone against LHP this season — lowest in MLB.

Tigers hitters have drawn walks in 10% of their PA’s against LHP this season — 5th best in MLB.

The Nationals have allowed 5.51 runs per game (430/78) at home this season — 3rd highest in MLB.

Opponents have a miss rate of just 23% against Nationals pitchers this season — tied for 4th lowest in MLB.

The Nationals have allowed 1.88 runs per game (293/156) in late innings this season — highest in MLB.

Nationals pitchers have an ERA of 5.03 (711.0 IP) at home this season — 3rd highest in MLB.

Opponents have a groundball rate of 45% against Tigers pitchers this season — 2nd highest in MLB.

Tigers pitchers have an ERA of 3.32 (681.1 IP) at home this season — 2nd best in MLB.

Tigers pitchers have allowed a run just 27% of the time after their offense scores this season — 4th lowest in MLB.

Opponents have a groundball batting average of just .235 against Tigers pitchers this season — 4th best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.