• The Orioles are -140 favorites vs the White Sox
• Orioles vs White Sox Over / Under today: 7 Runs
• Orioles / White Sox TV Channel: MASN | CHS+

The Baltimore Orioles (-140) visit Rate Field to take on the Chicago White Sox (+115) on April 7, 2026. First pitch is scheduled for 3:10 pm in Chicago, IL.

This season, the Orioles are 4-6 against the spread (ATS), while the White Sox are 5-5 ATS.

Orioles vs White Sox Starting Pitchers Today:

• Orioles starting pitcher: Trevor Rogers 2-0, 1.39 ERA
• White Sox starting pitcher: Shane Smith 0-2, 19.31 ERA

Orioles vs. White Sox Odds, Run Line, Over/Under & Moneyline

Orioles vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Orioles vs White Sox and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Orioles players for Tuesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Trevor Rogers has hit the Earned Runs Under in 14 of his last 15 games (+13.30 Units / 64% ROI)
• Trevor Rogers has hit the Hits Allowed Under in 12 of his last 15 games (+9.30 Units / 49% ROI)
• Trevor Rogers has hit the Pitching Outs Over in 12 of his last 15 games (+8.41 Units / 44% ROI)
• Trevor Rogers has hit the Strikeouts Over in 10 of his last 15 games (+6.10 Units / 37% ROI)
• Trevor Rogers has hit the Walks Allowed Over in 4 of his last 5 games (+3.65 Units / 61% ROI)

And here are some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

• Shane Smith has hit the Hits Allowed Under in 17 of his last 25 games (+8.25 Units / 28% ROI)
• Shane Smith has hit the Strikeouts Over in 16 of his last 25 games (+6.25 Units / 20% ROI)
• Shane Smith has hit the Walks Allowed Under in his last 4 games at home (+4.20 Units / 93% ROI)
• Shane Smith has hit the Earned Runs Under in 5 of his last 6 games at home (+3.50 Units / 44% ROI)
• Shane Smith has hit the Pitching Outs Over in 4 of his last 5 games at home (+3.20 Units / 45% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have hit the Game Total Under in 87 of their last 141 games (+30.03 Units / 19% ROI)
• The Baltimore Orioles have hit the Team Total Under in 84 of their last 142 games (+17.65 Units / 10% ROI)
• The Baltimore Orioles have hit the Moneyline in 59 of their last 112 games (+10.95 Units / 9% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Over in 25 of their last 39 away games (+10.75 Units / 23% ROI)
• The Baltimore Orioles have covered the Run Line in 45 of their last 76 games (+8.05 Units / 8% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 45 of their last 69 games at home (+16.45 Units / 19% ROI)
• The Chicago White Sox have covered the Run Line in 82 of their last 138 games (+15.05 Units / 8% ROI)
• The Chicago White Sox have hit the Team Total Over in 41 of their last 66 games (+13.60 Units / 18% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 29 of their last 71 games at home (+9.95 Units / 14% ROI)
• The Chicago White Sox have hit the Game Total Under in 11 of their last 16 games (+5.60 Units / 32% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 2-8 against the Run Line (-6.25 Units / -56.31% ROI).

• 4-6 when betting on the Moneyline for -4.25 Units / -37.61% ROI
• 5-5 when betting on the total runs Over for +0.55 Units / 5.58% ROI
• 5-5 when betting on the total runs Under for -1.6 Units / -16.08% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 5-5 against the Run Line (-3.7 Units / -28.35% ROI).

• 4-6 when betting on the Moneyline for +0.55 Units / 6.11% ROI
• 7-3 when betting on the total runs Over for +4.8 Units / 48.98% ROI
• 3-7 when betting on the total runs Under for -5.8 Units / -58% ROI

Orioles Keys to the Game vs. the White Sox

The Orioles are just 1-82 (.012) when trailing entering the 9th inning since the 2025 season — tied for 2nd lowest in MLB; League Avg: .042.

The Orioles were just 1-77 (.013) when trailing entering the 9th inning in the 2025 season — 3rd lowest in MLB; League Avg: .043.

The Orioles were just 63-10 (.863) when leading entering the 8th inning in the 2025 season — 5th lowest in MLB; League Avg: .909.

The Orioles were just 10-67 (.130) when they allowed 5 or more runs in the 2025 season — 4th lowest in MLB; League Avg: .202.

White Sox Keys to the Game vs. the Orioles

The White Sox are just 84-38 (.689) when leading entering the 7th inning since the 2024 season — lowest in MLB; League Avg: .867.

The White Sox are just 64-164 (.281) after a loss since the 2024 season — lowest in MLB; League Avg: .492.

The White Sox are just 105-229 (.314) since the 2024 season — lowest in MLB; League Avg: .500.

The White Sox are just 101-194 (.342) when allowing 5 or more extra base hits since the 2024 season — lowest in MLB; League Avg: .536.

Orioles Hitting Stats & Trends

Orioles hitters struck out in 24% of their PA’s in the 2025 season — 3rd highest in MLB.

Orioles hitters slugged just .189 on pitches out of the zone in the 2025 season — 5th lowest in MLB.

Orioles hitters had an OPS of just .671 (3,064 PA’s) on the road in the 2025 season — 4th lowest in MLB.

Orioles hitters have drawn walks in 7% of their PA’s against LHP since the 2025 season — tied for 4th lowest in MLB.

White Sox Hitting Stats & Trends

The White Sox have won just 47% of games in which they have scored first since the 2024 season — lowest in MLB.

White Sox hitters have an OPS of just .651 (13,687 PA’s) against RHP since the 2023 season — lowest in MLB.

White Sox hitters have an OPS of just .642 (9,091 PA’s) against RHP since the 2024 season — lowest in MLB.

White Sox hitters have an OBP of just .289 (9,091 PA’s) against RHP since the 2024 season — lowest in MLB.

Orioles Pitching Stats & Trends

Orioles pitchers have walked 11% of batters when facing the leadoff batter in the inning since the 2025 season — 2nd highest in MLB.

Orioles pitchers walked 10% of batters when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

Orioles pitchers have walked 12% of batters this season — tied for 5th highest in MLB.

Orioles pitchers allowed an OBP of .352 (1,434 PA’s) when facing the leadoff batter in the inning in the 2025 season — 2nd highest in MLB.

White Sox Pitching Stats & Trends

The White Sox have won just 9% of road games in which their opponents scored first since the 2024 season — lowest in MLB.

Opponents have a miss rate of just 20% against White Sox pitchers this season — 2nd lowest in MLB.

White Sox pitchers have an ERA of 8.63 (49.0 IP) on the road this season — highest in MLB.

The White Sox have won just 15% of games in which their opponents scored first since the 2024 season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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