• The Cubs are -150 favorites vs the Pirates
• Pirates vs Cubs Over / Under today: 6.5 Runs
• Pirates / Cubs TV Channel: MARQ | SNPT

The Pittsburgh Pirates (+125) visit Wrigley Field to take on the Chicago Cubs (-150) on April 11, 2026. First pitch is scheduled for 2:20 pm in Chicago, IL.

This season, the Pirates are 8-5 against the spread (ATS), while the Cubs are 5-8 ATS.

Pirates vs Cubs Starting Pitchers Today:

• Pirates starting pitcher: Braxton Ashcraft 1-1, 2.25 ERA
• Cubs starting pitcher: Edward Cabrera 1-0, 0.00 ERA

Pirates vs. Cubs Odds, Run Line, Over/Under & Moneyline

Pirates vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Saturday‘s MLB game with 58.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Pirates vs Cubs and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Pirates players for Saturday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

• Bryan Reynolds has hit the Home Runs Over in 3 of his last 4 away games (+15.80 Units / 395% ROI)
• Oneil Cruz has hit the Hits Over in his last 9 games (+9.00 Units / 57% ROI)
• Bryan Reynolds has hit the Runs Over in 12 of his last 20 games (+8.40 Units / 42% ROI)
• Oneil Cruz has hit the Singles Over in 12 of his last 20 games (+7.85 Units / 39% ROI)
• Bryan Reynolds has hit the Walks Under in 9 of his last 10 away games (+7.30 Units / 34% ROI)

And here are some favorite MLB player prop bets for Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

• Seiya Suzuki has hit the Home Runs Over in 5 of his last 10 games at home (+18.90 Units / 189% ROI)
• Ian Happ has hit the Singles Under in 20 of his last 25 games (+12.50 Units / 31% ROI)
• Seiya Suzuki has hit the Hits Over in 14 of his last 15 games (+12.45 Units / 46% ROI)
• Seiya Suzuki has hit the Total Bases Over in 13 of his last 15 games (+11.70 Units / 55% ROI)
• Alex Bregman has hit the Runs Under in 13 of his last 15 games (+10.55 Units / 46% ROI)

Pirates Best Bets Today:

• The Pittsburgh Pirates have covered the Run Line in 32 of their last 50 games (+10.70 Units / 15% ROI)
• The Pittsburgh Pirates have hit the Game Total Under in 30 of their last 50 away games (+10.60 Units / 20% ROI)
• The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 31 of their last 50 away games (+9.85 Units / 16% ROI)
• The Pittsburgh Pirates have hit the Moneyline in 14 of their last 21 games (+8.95 Units / 39% ROI)
• The Pittsburgh Pirates have covered the 1st Five Innings (F5) Run Line in 15 of their last 21 games (+8.25 Units / 34% ROI)

Cubs Best Bets Today:

• The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 31 of their last 50 games at home (+12.10 Units / 15% ROI)
• The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 31 of their last 50 games at home (+10.35 Units / 18% ROI)
• The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 games at home (+6.95 Units / 18% ROI)
• The Chicago Cubs have hit the Team Total Over in 14 of their last 21 games at home (+6.65 Units / 28% ROI)
• The Chicago Cubs have covered the Run Line in 10 of their last 15 games at home (+6.25 Units / 35% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 8-5 against the Run Line (+2.25 Units / 12.61% ROI).

• 8-5 when betting on the Moneyline for +3.55 Units / 23.99% ROI
• 7-6 when betting on the total runs Over for +0.35 Units / 2.46% ROI
• 6-7 when betting on the total runs Under for -1.85 Units / -12.85% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 5-8 against the Run Line (-2.6 Units / -18.18% ROI).

• 6-7 when betting on the Moneyline for -4.9 Units / -24.2% ROI
• 6-6 when betting on the total runs Over for -0.35 Units / -2.46% ROI
• 6-6 when betting on the total runs Under for -0.7 Units / -4.83% ROI

Pirates Keys to the Game vs. the Cubs

The Pirates were just 1-80 (.012) when trailing entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .043.

The Pirates are just 14-73 (.161) when allowing 2 or more home runs since the 2024 season — lowest in MLB; League Avg: .293.

The Pirates are 8-5 (.615) this season — tied for 3rd best in MLB; League Avg: .500.

The Pirates are just 14-90 (.135) when allowing 10 or more hits since the 2024 season — 2nd lowest in MLB; League Avg: .250.

Cubs Keys to the Game vs. the Pirates

The Cubs are 51-25 (.671) after a loss since the 2025 season — best in MLB; League Avg: .482.

The Cubs were 48-6 (.889) when they had 10 or more hits in the 2025 season — best in MLB; League Avg: .743.

The Cubs are 42-9 (.824) when they’ve scored in the first inning since the 2025 season — best in MLB; League Avg: .639.

The Cubs are 74-19 (.796) when they’ve scored in the first inning since the 2024 season — best in MLB; League Avg: .640.

Pirates Hitting Stats & Trends

Pirates hitters slugged just .333 on the road in the 2025 season — 2nd lowest in MLB.

The Pirates batted just .121 in lefty-lefty matchups in the 2025 season — lowest in MLB.

Pirates hitters are slugging just .158 on pitches out of the zone since the 2025 season — lowest in MLB.

Pirates hitters had an OPS of just .634 (1,471 PA’s) against LHP in the 2025 season — 2nd lowest in MLB.

Cubs Hitting Stats & Trends

Cubs hitters have drawn walks in 14% of their PA’s against LHP this season — 2nd best in MLB.

Cubs hitters slugged .434 against LHP in the 2025 season — 4th best in MLB.

Cubs hitters had an OPS of .761 (3,167 PA’s) on the road in the 2025 season — 3rd best in MLB.

Cubs hitters slugged .441 on the road in the 2025 season — 3rd best in MLB.

Pirates Pitching Stats & Trends

Pirates pitchers have walked 19% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Pirates pitchers have a strikeout rate of 34% in late innings this season — best in MLB.

Pirates pitchers have walked 12% of batters this season — 5th highest in MLB.

Pirates pitchers won only 14% of games in which they allowed their opponent to score in three different innings in the 2025 season — 2nd lowest in MLB.

Cubs Pitching Stats & Trends

Cubs pitchers walked 7% of batters in the 2025 season — best in MLB.

Cubs pitchers have a strikeout rate of just 7% in close and late situations this season — lowest in MLB.

Cubs pitchers have walked 7% of batters since the 2025 season — best in MLB.

Cubs pitchers picked-off 27 runners in the 2025 season — most in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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