Rays vs Yankees Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

New York Yankees' Jazz Chisholm Jr. reacts after connecting for a solo home run against the Toronto Blue Jays during the fifth inning of Game 3 of baseball's American League Division Series, Tuesday, Oct. 7, 2025, in New York.
(AP Photo/Frank Franklin II)
Postseason Betting Promos
  • The Yankees are -135 favorites vs the Rays
  • Rays vs Yankees Over / Under today: 6.5 Runs
  • Rays / Yankees TV Channel: RATV | YES

The Tampa Bay Rays (+110) visit Yankee Stadium to take on the New York Yankees (-135) on September 22, 2026. First pitch is scheduled for 1:05 pm in Bronx, NY.

This season, the Rays are 95-60 against the spread (ATS), while the Yankees are 78-76 ATS.

Rays vs Yankees Starting Pitchers Today:

  • Rays starting pitcher: Nick Martinez 15-4, 2.96 ERA
  • Yankees starting pitcher: Carlos Rodon 6-3, 2.94 ERA

Rays vs. Yankees Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Rays+1.5 -220O 6.5 -115+110
Yankees -1.5 +180U 6.5 -105-135

Rays vs Yankees Prediction for Today’s Game

Based on recent trends the model predicts the Yankees will win Tuesday‘s MLB game with 57.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Rays players for Tuesday‘s game, looking at profitable historical betting trends:

Best Rays Player Prop Bets Today:

  • Nick Martinez has hit the Walks Allowed Under in 21 of his last 25 games (+18.60 Units / 49% ROI)
  • Liam Hicks has hit the Home Runs Over in 3 of his last 10 away games (+15.40 Units / 154% ROI)
  • Liam Hicks has hit the Hits Over in 16 of his last 20 away games (+11.00 Units / 30% ROI)
  • Nick Martinez has hit the Pitching Outs Over in 18 of his last 25 games (+10.15 Units / 35% ROI)
  • Jonny DeLuca has hit the Total Bases Over in 14 of his last 20 away games (+9.85 Units / 39% ROI)

And here are some favorite MLB player prop bets for Yankees players for Tuesday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Best Bets Today:

  • George Lombard Jr. has hit the Home Runs Over in 3 of his last 10 games (+19.30 Units / 193% ROI)
  • Heliot Ramos has hit the Hits Runs and RBIs Under in 20 of his last 25 games at home (+14.95 Units / 49% ROI)
  • Ryan McMahon has hit the Runs Under in 18 of his last 20 games (+14.20 Units / 34% ROI)
  • Heliot Ramos has hit the Singles Under in 19 of his last 25 games (+10.55 Units / 32% ROI)
  • Luis Garcรญa Jr. has hit the RBIs Under in 13 of his last 15 games (+10.05 Units / 34% ROI)
  • The Tampa Bay Rays have covered the Run Line in 25 of their last 40 away games (+13.95 Units / 28% ROI)
  • The Tampa Bay Rays have hit the Moneyline in 18 of their last 25 away games (+10.10 Units / 32% ROI)
  • The Tampa Bay Rays have covered the 1st Five Innings (F5) Run Line in 26 of their last 40 away games (+9.65 Units / 19% ROI)
  • The Tampa Bay Rays have hit the 1st Five Innings (F5) Moneyline in 21 of their last 40 away games (+8.55 Units / 17% ROI)
  • The Tampa Bay Rays have hit the Game Total Under in 30 of their last 50 away games (+8.10 Units / 15% ROI)
  • The New York Yankees have covered the Run Line in 24 of their last 40 games (+13.40 Units / 29% ROI)
  • The New York Yankees have hit the Team Total Under in 33 of their last 50 games at home (+13.10 Units / 22% ROI)
  • The New York Yankees have hit the Game Total Over in 15 of their last 20 games (+10.75 Units / 50% ROI)
  • The New York Yankees have hit the 1st Five Innings (F5) Team Total Under in 26 of their last 40 games at home (+9.75 Units / 20% ROI)
  • The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 games (+7.35 Units / 9% ROI)

Rays Against the Spread (ATS) Record

Against the spread this season, the Rays are 81-71 against the Run Line (+21.15 Units / 11.53% ROI).

  • 95-60 when betting on the Moneyline for +21.8 Units / 10.7% ROI
  • 69-80 when betting on the total runs Over for -18.6 Units / -10.94% ROI
  • 80-69 when betting on the total runs Under for +3.8 Units / 2.22% ROI

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 78-76 against the Run Line (+11.45 Units / 6.51% ROI).

  • 89-66 when betting on the Moneyline for -3.9 Units / -1.7% ROI
  • 71-79 when betting on the total runs Over for -16.3 Units / -9.54% ROI
  • 79-71 when betting on the total runs Under for +1.05 Units / 0.62% ROI

Rays Keys to the Game vs. the Yankees

The Rays are 39-5 (.886) when they’ve hit 2 or more home runs this season — best in MLB.

The Rays are 62-32 (.660) after a win this season — best in MLB.

The Rays are 37-48 (.435) when scoring 4 or fewer runs this season — best in MLB.

The Rays are 13-48 (.213) when trailing entering the 7th inning this season — 3rd best in MLB.

Yankees Keys to the Game vs. the Rays

The Yankees are 38-4 (.905) when they’ve had 10 or more hits this season — best in MLB.

The Yankees are 53-8 (.869) when they’ve hit 2 or more home runs this season — 2nd best in MLB.

The Yankees are 58-6 (.906) when scoring 5 or more runs this season — best in MLB.

The Yankees are 89-66 (.574) this season — 5th best in MLB.

The Rays are batting .266 with two outs this season — best in MLB.

The Rays are batting .197 on pitches out of the zone this season — best in MLB.

Rays hitters have put 40% of their swings in play this season — highest in MLB.

The Rays are batting .259 this season — best in MLB.

The Yankees are batting just .124 on pitches out of the zone this season — lowest in MLB.

Yankees hitters have an OBP of just .230 (3,164 PA’s) with two-strikes this season — lowest in MLB.

Yankees hitters are slugging just .175 on pitches out of the zone this season — lowest in MLB.

Yankees hitters have an OPS of .769 (1,854 PA’s) in innings 7-9 this season — 2nd best in MLB.

Rays pitchers have walked 7% of batters this season — best in MLB.

Rays pitchers have a first-pitch strike rate of 65% this season — 2nd highest in MLB.

Rays pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — best in MLB.

Rays pitchers have allowed three-ball counts to 17% of batters they faced (952/5,689 PA’s) this season — lowest in MLB.

Opponents have a groundball rate of 45% against Yankees pitchers this season — 5th highest in MLB.

Yankees pitchers have an ERA of 2.94 (716.1 IP) on the road this season — best in MLB.

The Yankees have allowed 3.44 runs per game (279/81) on the road this season — best in MLB.

Yankees pitchers have an ERA of 3.22 (1387.1 IP) this season — best in MLB.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.