• The Mariners are -155 favorites vs the Reds
• Reds vs Mariners Over / Under today: 8 Runs
• Reds / Mariners TV Channel: MRTV | RDTV

The Cincinnati Reds (+125) visit T-Mobile Park to take on the Seattle Mariners (-155) on July 22, 2026. First pitch is scheduled for 3:40 pm in Seattle, WA.

This season, the Reds are 46-54 against the spread (ATS), while the Mariners are 41-61 ATS.

Reds vs Mariners Starting Pitchers Today:

• Reds starting pitcher: Brady Singer 4-9, 4.57 ERA
• Mariners starting pitcher: Emerson Hancock 6-4, 3.18 ERA

Reds vs. Mariners Odds, Run Line, Over/Under & Moneyline

Reds vs Mariners Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Wednesday‘s MLB game with 57.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Reds players for Wednesday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

• Nate Lowe has hit the Home Runs Over in 3 of his last 4 games (+13.10 Units / 328% ROI)
• TJ Friedl has hit the Hits Under in 17 of his last 25 games (+11.60 Units / 44% ROI)
• Noelvi Marte has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+10.55 Units / 37% ROI)
• JJ Bleday has hit the Singles Over in 13 of his last 20 games (+10.15 Units / 50% ROI)
• Nate Lowe has hit the Total Bases Over in 18 of his last 25 away games (+9.90 Units / 28% ROI)

And here are some favorite MLB player prop bets for Mariners players for Wednesday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

• Cole Young has hit the Home Runs Over in 3 of his last 8 games (+18.00 Units / 225% ROI)
• Luke Raley has hit the Runs Under in 22 of his last 25 games (+17.55 Units / 37% ROI)
• Cal Raleigh has hit the Total Bases Under in 17 of his last 20 games at home (+14.90 Units / 60% ROI)
• Colt Emerson has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+11.90 Units / 39% ROI)
• Josh Naylor has hit the Singles Over in 18 of his last 25 games (+10.00 Units / 34% ROI)

Reds Best Bets Today:

• The Cincinnati Reds have hit the Team Total Under in 29 of their last 45 games (+11.30 Units / 21% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 30 away games (+9.55 Units / 26% ROI)
• The Cincinnati Reds have hit the Game Total Over in 28 of their last 45 away games (+9.25 Units / 19% ROI)
• The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 22 of their last 35 games (+7.80 Units / 19% ROI)
• The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 14 of their last 30 away games (+6.85 Units / 20% ROI)

Mariners Best Bets Today:

• The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 30 games (+10.95 Units / 30% ROI)
• The Seattle Mariners have hit the Team Total Under in 26 of their last 40 games (+10.75 Units / 23% ROI)
• The Seattle Mariners have hit the Moneyline in 17 of their last 24 games at home (+7.90 Units / 22% ROI)
• The Seattle Mariners have hit the Game Total Over in 21 of their last 40 games (+4.65 Units / 10% ROI)
• The Seattle Mariners have covered the Run Line in 10 of their last 19 games at home (+3.55 Units / 17% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 54-45 against the Run Line (-3.9 Units / -2.77% ROI).

• 46-54 when betting on the Moneyline for -7.9 Units / -7.07% ROI
• 56-43 when betting on the total runs Over for +8.65 Units / 7.82% ROI
• 43-56 when betting on the total runs Under for -18 Units / -16.45% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 41-61 against the Run Line (-11.6 Units / -10.44% ROI).

• 51-51 when betting on the Moneyline for -14.7 Units / -10.54% ROI
• 49-47 when betting on the total runs Over for -2.5 Units / -2.22% ROI
• 47-49 when betting on the total runs Under for -6.6 Units / -5.9% ROI

Mariners vs Reds Home Run Prop Bets Today

Mariners vs Reds Total Hits Prop Bets Today

Mariners vs Reds Strikeout Prop Bets Today

Reds Keys to the Game vs. the Mariners

The Reds are just 3-15 (.167) when tied entering the 7th inning this season — lowest in MLB; League Avg: .500.

The Reds are just 8-43 (.157) when allowing 5 or more runs this season — 5th lowest in MLB; League Avg: .207.

The Reds are just 6-11 (.353) when tied entering the 8th inning this season — 5th lowest in MLB; League Avg: .500.

The Reds are just 5-28 (.152) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .247.

Mariners Keys to the Game vs. the Reds

The Mariners are just 15-27 (.357) vs bottom 10 scoring offenses this season Today, they face the Reds (23rd in runs scored).

The Mariners are just 1-45 (.022) when trailing entering the 9th inning this season — 3rd lowest in MLB; League Avg: .053.

The Mariners are just 6-35 (.146) when allowing 5 or more runs this season — 4th lowest in MLB; League Avg: .207.

The Mariners are just 1-41 (.024) when trailing entering the 8th inning this season — 3rd lowest in MLB; League Avg: .097.

Reds Hitting Stats & Trends

The Reds are batting just .217 with runners on base this season — lowest in MLB.

The Reds are batting just .212 with two outs this season — lowest in MLB.

The Reds are batting just .118 on pitches out of the zone this season — lowest in MLB.

Reds hitters have an OBP of just .300 (1,650 PA’s) with runners on base this season — lowest in MLB.

Mariners Hitting Stats & Trends

The Mariners are batting just .216 against LHP this season — 2nd lowest in MLB.

Mariners hitters are slugging just .334 against LHP this season — lowest in MLB.

Mariners hitters have an OPS of just .635 (1,078 PA’s) against LHP this season — lowest in MLB.

Mariners hitters are slugging just .378 this season — 2nd lowest in MLB.

Reds Pitching Stats & Trends

Reds pitchers have walked 11% of batters this season — 2nd highest in MLB.

Reds pitchers have a first-pitch strike rate of just 58% this season — lowest in MLB.

Reds pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 5th highest in MLB.

The Reds pitchers have allowed their opponents to score first in 58% of their games this season — 4th highest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have walked 7% of batters this season — best in MLB.

Mariners pitchers have a first-pitch strike rate of 66% this season — highest in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 69% of opposing batters this season — highest in MLB.

Mariners pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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