• The Diamondbacks are -200 favorites vs the Rockies
• Rockies vs Diamondbacks Over / Under today: 9.5 Runs
• Rockies / Diamondbacks TV Channel: DBTV | ROTV | KPNX

The Colorado Rockies (+165) visit Chase Field to take on the Arizona Diamondbacks (-200) on May 21, 2026. First pitch is scheduled for 9:40 pm in Phoenix, AZ.

This season, the Rockies are 19-31 against the spread (ATS), while the Diamondbacks are 30-17 ATS.

Rockies vs Diamondbacks Starting Pitchers Today:

• Rockies starting pitcher: Zach Agnos 0-0, 5.59 ERA
• Diamondbacks starting pitcher: Eduardo Rodriguez 4-1, 2.55 ERA

Rockies vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Rockies vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Diamondbacks will win Thursday‘s MLB game with 61.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Rockies vs Diamondbacks and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Rockies players for Thursday‘s game, looking at profitable historical betting trends:

Best Rockies Player Prop Bets Today:

• Jake McCarthy has hit the Total Bases Over in 15 of his last 20 games (+11.40 Units / 46% ROI)
• Jake McCarthy has hit the Hits Runs and RBIs Over in 15 of his last 20 games (+10.00 Units / 42% ROI)
• Jake McCarthy has hit the Hits Over in 16 of his last 20 games (+8.65 Units / 25% ROI)
• Mickey Moniak has hit the Runs Under in 15 of his last 20 games (+7.85 Units / 25% ROI)
• T.J. Rumfield has hit the Singles Over in 13 of his last 20 away games (+7.55 Units / 37% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Thursday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Jorge Barrosa has hit the Singles Under in 20 of his last 25 games (+12.30 Units / 30% ROI)
• Jose Fernandez has hit the Hits Over in 19 of his last 25 games (+10.30 Units / 23% ROI)
• Lourdes Gurriel Jr. has hit the Total Bases Under in 15 of his last 20 games at home (+8.35 Units / 28% ROI)
• Ketel Marte has hit the Walks Under in 15 of his last 20 games at home (+7.85 Units / 27% ROI)
• Eduardo Rodriguez has hit the Walks Allowed Over in 17 of his last 25 games (+7.85 Units / 23% ROI)

Rockies Best Bets Today:

• The Colorado Rockies have hit the Team Total Under in 30 of their last 50 away games (+8.15 Units / 14% ROI)
• The Colorado Rockies have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 17 away games (+7.10 Units / 36% ROI)
• The Colorado Rockies have hit the Moneyline in 7 of their last 13 away games (+5.65 Units / 43% ROI)
• The Colorado Rockies have hit the Game Total Over in 13 of their last 21 games (+5.30 Units / 23% ROI)
• The Colorado Rockies have covered the 1st Five Innings (F5) Run Line in 27 of their last 50 games (+1.35 Units / 2% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 29 of their last 40 games at home (+15.90 Units / 32% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 26 of their last 40 games (+10.65 Units / 23% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 31 of their last 50 games at home (+10.40 Units / 17% ROI)
• The Arizona Diamondbacks have covered the Run Line in 30 of their last 50 games at home (+10.25 Units / 16% ROI)
• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 26 of their last 50 games at home (+9.00 Units / 14% ROI)

Rockies Against the Spread (ATS) Record

Against the spread this season, the Rockies are 26-24 against the Run Line (-2.9 Units / -4.64% ROI).

• 19-31 when betting on the Moneyline for -0.45 Units / -0.9% ROI
• 23-26 when betting on the total runs Over for -5.8 Units / -10.5% ROI
• 26-23 when betting on the total runs Under for +0.75 Units / 1.37% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 30-17 against the Run Line (+8.5 Units / 12.57% ROI).

• 25-23 when betting on the Moneyline for +2.65 Units / 4.92% ROI
• 25-21 when betting on the total runs Over for +2 Units / 3.77% ROI
• 21-25 when betting on the total runs Under for -6.3 Units / -11.95% ROI

Diamondbacks vs Rockies Home Run Prop Bets Today

Diamondbacks vs Rockies Total Hits Prop Bets Today

Diamondbacks vs Rockies Strikeout Prop Bets Today

Rockies Keys to the Game vs. the Diamondbacks

The Rockies are just 19-31 (.380) this season — 2nd lowest in MLB; League Avg: .500.

The Rockies are just 4-14 (.222) when their opponents score in the first inning this season — 3rd lowest in MLB; League Avg: .365.

The Rockies are just 0-25 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .055.

The Rockies are just 18-24 (.429) when allowing 5 or more extra base hits this season — 5th lowest in MLB; League Avg: .532.

Diamondbacks Keys to the Game vs. the Rockies

The Diamondbacks are 5-15 (.250) when trailing entering the 7th inning this season — tied for 2nd best in MLB; League Avg: .137.

The Diamondbacks are just 79-21 (.790) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .872.

The Diamondbacks are just 87-15 (.853) when leading entering the 8th inning since the 2025 season — 3rd lowest in MLB; League Avg: .905.

The Diamondbacks are 7-84 (.077) when trailing entering the 9th inning since the 2025 season — 3rd best in MLB; League Avg: .046.

Rockies Hitting Stats & Trends

Rockies hitters have struck out in 30% of their PA’s against LHP this season — highest in MLB.

The Rockies are batting just .205 when facing the starting pitcher for the 3rd time in a game this season — 2nd lowest in MLB.

Rockies hitters have put just 30% of their swings in play against LHP this season — lowest in MLB.

Rockies hitter’ K:BB ratio is 5.1 against LHP this season — highest in MLB.

Diamondbacks Hitting Stats & Trends

The Diamondbacks are batting .276 against LHP this season — best in MLB.

The Diamondbacks are batting .337 in lefty-lefty matchups this season — best in MLB.

Diamondbacks hitters have struck out in just 17% of their PA’s against LHP this season — best in MLB.

9% of Diamondbacks’ hitters plate appearances have lasted only one pitch (157/1,777 PA’s) this season — lowest in MLB.

Rockies Pitching Stats & Trends

The longest HR allowed by the Rockies pitchers this season traveled 505.5 feet — — longest in MLB

Rockies pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

Opponents are hitting .277 against Rockies pitchers this season — highest in MLB.

Rockies pitchers have a strikeout rate of just 38% with two-strikes this season — 3rd lowest in MLB.

Diamondbacks Pitching Stats & Trends

Diamondbacks pitchers have walked 6% of batters when facing the leadoff batter in the inning this season — tied for 2nd best in MLB.

Diamondbacks pitchers have walked 8% of batters this season — 4th best in MLB.

Diamondbacks pitchers have a strikeout rate of just 19% with runners in scoring position this season — tied for 3rd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 20% this season — tied for 3rd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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