• The Astros are -145 favorites vs the Royals
• Royals vs Astros Over / Under today: 8.5 Runs
• Royals / Astros TV Channel: RYTV | SCHN

The Kansas City Royals (+118) visit Daikin Park to take on the Houston Astros (-145) on September 16, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the Royals are 66-85 against the spread (ATS), while the Astros are 78-73 ATS.

Royals vs Astros Starting Pitchers Today:

• Royals starting pitcher: Daniel Lynch 5-5, 3.52 ERA
• Astros starting pitcher: Cristian Javier 2-5, 5.50 ERA

Royals vs. Astros Odds, Run Line, Over/Under & Moneyline

Royals vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Wednesday‘s MLB game with 54.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Royals vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Royals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Bets Today:

• Carter Jensen has hit the Home Runs Over in 4 of his last 10 games (+12.90 Units / 129% ROI)
• Isaac Collins has hit the Singles Under in 20 of his last 25 away games (+12.25 Units / 30% ROI)
• Bobby Witt Jr. has hit the Hits Under in 18 of his last 25 away games (+11.25 Units / 24% ROI)
• Carter Jensen has hit the Total Bases Over in 15 of his last 20 games (+11.20 Units / 45% ROI)
• John Rave has hit the Hits Runs and RBIs Under in 9 of his last 10 away games (+8.45 Units / 66% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Christian Vazquez has hit the Home Runs Over in 2 of his last 7 games at home (+18.00 Units / 257% ROI)
• Christian Walker has hit the Runs Under in 21 of his last 25 games (+12.85 Units / 27% ROI)
• Christian Walker has hit the Total Bases Under in 17 of his last 25 games (+11.85 Units / 45% ROI)
• Daulton Varsho has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+11.35 Units / 35% ROI)
• Jeremy Pena has hit the Hits Under in 15 of his last 20 games at home (+11.35 Units / 30% ROI)

Royals Best Bets Today:

• The Kansas City Royals have hit the Team Total Under in 30 of their last 45 away games (+13.75 Units / 26% ROI)
• The Kansas City Royals have hit the Game Total Under in 29 of their last 50 games (+10.55 Units / 19% ROI)
• The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 23 of their last 35 away games (+8.95 Units / 20% ROI)
• The Kansas City Royals have covered the Run Line in 30 of their last 50 games (+8.60 Units / 13% ROI)
• The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 12 of their last 23 games (+5.25 Units / 20% ROI)

Astros Best Bets Today:

• The Houston Astros have covered the Run Line in 30 of their last 50 games (+12.50 Units / 19% ROI)
• The Houston Astros have hit the Team Total Under in 12 of their last 15 games at home (+8.85 Units / 51% ROI)
• The Houston Astros have hit the Game Total Under in 12 of their last 15 games at home (+8.75 Units / 53% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 25 games at home (+6.90 Units / 25% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 17 of their last 30 games at home (+4.85 Units / 11% ROI)

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are 72-73 against the Run Line (-19.45 Units / -9.34% ROI).

• 66-85 when betting on the Moneyline for -18.35 Units / -10.92% ROI
• 66-80 when betting on the total runs Over for -21.55 Units / -12.96% ROI
• 80-66 when betting on the total runs Under for +8.05 Units / 4.85% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 78-73 against the Run Line (-0.5 Units / -0.25% ROI).

• 76-75 when betting on the Moneyline for -8.1 Units / -4.49% ROI
• 74-68 when betting on the total runs Over for -1.8 Units / -1.07% ROI
• 68-74 when betting on the total runs Under for -13.1 Units / -7.95% ROI

Royals Keys to the Game vs. the Astros

The Royals are just 9-47 (.161) when allowing 10 or more hits this season — 4th lowest in MLB.

The Royals are just 56-8 (.875) when leading entering the 9th inning this season — 4th lowest in MLB.

The Royals are just 27-49 (.355) on the road this season — 4th lowest in MLB.

The Royals are just 8-33 (.195) when allowing 2 or more home runs this season — 3rd lowest in MLB.

Astros Keys to the Game vs. the Royals

The Astros are 65-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Astros are 13-6 (.684) when tied entering the 8th inning this season — best in MLB.

The Astros are just 24-32 (.429) vs the bottom 10 runs allowed teams this season Today, they face the Royals (25th fewest runs allowed).

The Astros are 56-4 (.933) when leading entering the 7th inning this season — tied for 2nd best in MLB.

Royals Hitting Stats & Trends

Royals hitters are slugging just .365 on the road this season — 2nd lowest in MLB.

Royals hitters have an OBP of just .298 (2,876 PA’s) on the road this season — tied for 2nd lowest in MLB.

The Royals are batting just .228 on the road this season — tied for 2nd lowest in MLB.

Royals hitters have an OPS of just .663 (2,876 PA’s) on the road this season — 3rd lowest in MLB.

Astros Hitting Stats & Trends

Astros hitters have 44 extra-base hits out of 170 total hits (just 26%) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

29% of Astros hitters strikeouts have come on 95+ MPH fastballs this season — 2nd highest in MLB.

Astros hitters have an OBP of just .236 (2,979 PA’s) with two-strikes this season — tied for 3rd lowest in MLB.

The Astros have scored first in just 39% of their games against division opponents this season — 2nd lowest in MLB.

Royals Pitching Stats & Trends

Royals pitchers have a strikeout rate of just 37% with two-strikes this season — 2nd lowest in MLB.

Royals pitchers have a strikeout rate of just 19% in late innings this season — lowest in MLB.

Opponents have a miss rate of just 23% against Royals pitchers this season — 3rd lowest in MLB.

Royals pitchers have a strikeout rate of just 19% this season — 3rd lowest in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — highest in MLB.

Astros pitchers have walked 10% of batters this season — tied for highest in MLB.

Opponents have a groundball rate of just 39% against Astros pitchers this season — 2nd lowest in MLB.

The Astros have won just 28% of home games in which their opponents scored first this season — tied for 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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