• The Twins are -125 favorites vs the Angels
• Twins vs Angels Over / Under today: 8 Runs
• Twins / Angels TV Channel: TWTV | ABTV

The Minnesota Twins (-125) visit Angel Stadium of Anaheim to take on the Los Angeles Angels (+105) on September 18, 2026. First pitch is scheduled for 9:38 pm in Anaheim, CA.

This season, the Twins are 71-82 against the spread (ATS), while the Angels are 78-74 ATS.

Twins vs Angels Starting Pitchers Today:

• Twins starting pitcher: Connor Prielipp 5-7, 5.28 ERA
• Angels starting pitcher: Grayson Rodriguez 4-7, 6.13 ERA

Twins vs. Angels Odds, Run Line, Over/Under & Moneyline

Twins vs Angels Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Friday‘s MLB game with 54.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Twins players for Friday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Royce Lewis has hit the Runs Under in 22 of his last 25 games (+16.00 Units / 37% ROI)
• Royce Lewis has hit the Hits Runs and RBIs Under in 13 of his last 15 away games (+11.10 Units / 56% ROI)
• Royce Lewis has hit the Total Bases Under in 17 of his last 25 games (+9.95 Units / 32% ROI)
• Walker Jenkins has hit the Singles Under in 13 of his last 15 games (+9.55 Units / 38% ROI)
• Luke Keaschall has hit the Hits Over in 18 of his last 25 away games (+9.05 Units / 20% ROI)

And here are some favorite MLB player prop bets for Angels players for Friday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Best Bets Today:

• Wade Meckler has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+12.70 Units / 44% ROI)
• Christian Moore has hit the Runs Under in his last 10 games (+10.00 Units / 43% ROI)
• Mike Trout has hit the Walks Over in his last 6 games (+6.85 Units / 109% ROI)
• Vaughn Grissom has hit the RBIs Over in 4 of his last 5 games (+6.70 Units / 134% ROI)
• Jose Siri has hit the Hits Under in 11 of his last 15 games at home (+6.70 Units / 40% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 31 of their last 50 away games (+15.25 Units / 27% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 14 games (+5.65 Units / 33% ROI)
• The Minnesota Twins have hit the Team Total Under in 12 of their last 19 away games (+4.70 Units / 22% ROI)

Angels Best Bets Today:

• The Los Angeles Angels have hit the Game Total Under in 29 of their last 45 games (+12.15 Units / 24% ROI)
• The Los Angeles Angels have hit the 1st Five Innings (F5) Moneyline in 25 of their last 50 games at home (+9.30 Units / 16% ROI)
• The Los Angeles Angels have hit the Team Total Under in 30 of their last 50 games (+8.35 Units / 14% ROI)
• The Los Angeles Angels have covered the Run Line in 11 of their last 13 games (+8.10 Units / 41% ROI)
• The Los Angeles Angels have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 games at home (+7.75 Units / 13% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 79-72 against the Run Line (-12.3 Units / -5.67% ROI).

• 71-82 when betting on the Moneyline for -10.45 Units / -6.11% ROI
• 84-60 when betting on the total runs Over for +17.15 Units / 10.13% ROI
• 60-84 when betting on the total runs Under for -32.45 Units / -19.37% ROI

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are 78-74 against the Run Line (-18.5 Units / -8.69% ROI).

• 59-94 when betting on the Moneyline for -23.95 Units / -14.82% ROI
• 64-86 when betting on the total runs Over for -30.1 Units / -17.88% ROI
• 86-64 when betting on the total runs Under for +15.95 Units / 9.47% ROI

Twins Keys to the Game vs. the Angels

The Twins are just 26-22 (.542) when they’ve hit 2 or more home runs this season — 2nd lowest in MLB.

The Twins are just 14-9 (.609) when they’ve had 5 or more XBH this season — 2nd lowest in MLB.

The Twins are just 20-26 (.435) vs the bottom 10 runs allowed teams this season Today, they face the Angels (18th fewest runs allowed).

The Twins are just 16-40 (.286) when their opponents score in the first inning this season — 3rd lowest in MLB.

Angels Keys to the Game vs. the Twins

The Angels are just 4-16 (.200) when tied entering the 8th inning this season — lowest in MLB.

The Angels are just 7-64 (.099) when allowing 5 or more runs this season — lowest in MLB.

The Angels are just 52-11 (.825) when leading entering the 9th inning this season — lowest in MLB.

The Angels are just 5-18 (.217) when tied entering the 7th inning this season — 2nd lowest in MLB.

Twins Hitting Stats & Trends

The Twins are batting just .232 against LHP this season — 5th lowest in MLB.

Twins hitters are slugging just .279 on breaking pitches against LHP this season — lowest in MLB.

Twins hitters are slugging just .360 against LHP this season — 4th lowest in MLB.

The Twins are batting just .220 with two outs this season — 3rd lowest in MLB.

Angels Hitting Stats & Trends

Angels hitters have struck out in 26% of their PA’s against RHP this season — 2nd highest in MLB.

Angels hitters are slugging just .330 at home this season — lowest in MLB.

Angels hitters are slugging just .366 against RHP this season — lowest in MLB.

Angels hitters have an OPS of just .629 (2,857 PA’s) at home this season — lowest in MLB.

Twins Pitching Stats & Trends

Twins pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 3rd highest in MLB.

The Twins have allowed 5.47 runs per game (410/75) on the road this season — 2nd highest in MLB.

Opponents have a groundball rate of just 40% against Twins pitchers this season — tied for 3rd lowest in MLB.

Twins pitchers have an ERA of 5.20 (642.1 IP) on the road this season — 3rd highest in MLB.

Angels Pitching Stats & Trends

Angels pitchers have walked 10% of batters this season — tied for 2nd highest in MLB.

Opponents have a miss rate of 28% against Angels pitchers this season — 2nd best in MLB.

Angels pitchers have won only 16% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB.

Angels pitchers have allowed a run just 25% of the time after their offense scores this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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