• The Diamondbacks are -135 favorites vs the Twins
• Twins vs Diamondbacks Over / Under today: 9.5 Runs
• Twins / Diamondbacks TV Channel: PEAC

The Minnesota Twins (+110) visit Chase Field to take on the Arizona Diamondbacks (-135) on June 21, 2026. First pitch is scheduled for 3:15 pm in Phoenix, AZ.

This season, the Twins are 37-41 against the spread (ATS), while the Diamondbacks are 43-32 ATS.

Twins vs Diamondbacks Starting Pitchers Today:

• Twins starting pitcher: Mike Paredes 0-0, 4.20 ERA
• Diamondbacks starting pitcher: Jose Cabrera 0-0, 0.00 ERA

Twins vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Twins vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Sunday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs Diamondbacks and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Sunday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Victor Caratini has hit the Home Runs Over in 3 of his last 9 games (+19.00 Units / 211% ROI)
• Josh Bell has hit the Hits Over in 19 of his last 20 games (+16.95 Units / 43% ROI)
• Josh Bell has hit the Total Bases Over in 15 of his last 20 games (+15.10 Units / 69% ROI)
• Josh Bell has hit the Hits Runs and RBIs Over in 17 of his last 20 games (+13.65 Units / 61% ROI)
• Josh Bell has hit the Runs Over in 14 of his last 20 games (+13.40 Units / 67% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Sunday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Gabriel Moreno has hit the Home Runs Over in 3 of his last 10 games (+16.30 Units / 163% ROI)
• Lourdes Gurriel Jr. has hit the Total Bases Under in 20 of his last 25 games at home (+13.35 Units / 35% ROI)
• Nolan Arenado has hit the RBIs Under in 21 of his last 25 games (+13.35 Units / 26% ROI)
• Lourdes Gurriel Jr. has hit the Runs Under in 17 of his last 20 games at home (+12.25 Units / 38% ROI)
• Nolan Arenado has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+10.90 Units / 64% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Game Total Over in 26 of their last 35 away games (+17.30 Units / 45% ROI)
• The Minnesota Twins have hit the Team Total Over in 31 of their last 45 games (+16.05 Units / 31% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 games (+11.15 Units / 19% ROI)
• The Minnesota Twins have covered the Run Line in 22 of their last 35 games (+6.70 Units / 13% ROI)
• The Minnesota Twins have hit the Moneyline in 7 of their last 10 games (+4.70 Units / 44% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 37 of their last 50 games at home (+22.00 Units / 36% ROI)
• The Arizona Diamondbacks have hit the Game Total Under in 28 of their last 45 games (+12.85 Units / 26% ROI)
• The Arizona Diamondbacks have covered the Run Line in 27 of their last 45 games at home (+8.85 Units / 16% ROI)
• The Arizona Diamondbacks have hit the Moneyline in 27 of their last 45 games at home (+6.75 Units / 12% ROI)
• The Arizona Diamondbacks have hit the Team Total Over in 12 of their last 20 games at home (+3.50 Units / 15% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 43-35 against the Run Line (-3.25 Units / -2.87% ROI).

• 37-41 when betting on the Moneyline for -2.2 Units / -2.62% ROI
• 47-26 when betting on the total runs Over for +18.3 Units / 21.27% ROI
• 26-47 when betting on the total runs Under for -25.7 Units / -30.02% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 43-32 against the Run Line (+5.75 Units / 5.63% ROI).

• 39-37 when betting on the Moneyline for +0.3 Units / 0.33% ROI
• 33-39 when betting on the total runs Over for -9.65 Units / -11.51% ROI
• 39-33 when betting on the total runs Under for +3.1 Units / 3.71% ROI

Diamondbacks vs Twins Home Run Prop Bets Today

Diamondbacks vs Twins Total Hits Prop Bets Today

Diamondbacks vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the Diamondbacks

The Twins are just 0-34 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .055.

The Twins are just 2-8 (.200) when tied entering the 7th inning this season — 2nd lowest in MLB; League Avg: .500.

The Twins are just 0-31 (.000) when trailing entering the 8th inning this season — lowest in MLB; League Avg: .104.

The Twins are just 7-27 (.206) when tied entering the 7th inning since the 2025 season — lowest in MLB; League Avg: .500.

Diamondbacks Keys to the Game vs. the Twins

The Diamondbacks are 19-11 (.633) vs the bottom 10 runs allowed teams this season Today, they face the Twins (27th runs allowed).

The Diamondbacks are just 98-16 (.860) when leading entering the 8th inning since the 2025 season — 2nd lowest in MLB; League Avg: .905.

The Diamondbacks are just 87-22 (.798) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .871.

The Diamondbacks were just 67-7 (.905) when leading entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .956.

Twins Hitting Stats & Trends

The Twins are batting just .287 on the first pitch of at-bats this season — lowest in MLB.

Twins hitters have 49 extra-base hits out of 97 total hits (51%) on the first pitch of at-bats this season — best in MLB.

The Twins are batting just .215 with two outs this season — 2nd lowest in MLB.

Twins hitters have a 52% QAB rate with runners in scoring position this season — best in MLB.

Diamondbacks Hitting Stats & Trends

Diamondbacks hitters have struck out in just 16% of their PA’s against LHP this season — best in MLB.

Diamondbacks hitters are slugging .545 in lefty-lefty matchups this season — best in MLB.

Diamondbacks hitters have an OPS of just .667 (2,010 PA’s) against RHP this season — 2nd lowest in MLB.

The Diamondbacks are batting .269 against LHP this season — 2nd best in MLB.

Twins Pitching Stats & Trends

Opponents have a miss rate of just 23% against Twins pitchers this season — 4th lowest in MLB.

Opponents have a groundball rate of just 40% against Twins pitchers this season — tied for 2nd lowest in MLB.

Twins pitchers have an ERA of 5.59 (333.1 IP) on the road this season — highest in MLB.

Opponents have a chase percentage of just 27% against the Twins pitchers this season — lowest in MLB.

Diamondbacks Pitching Stats & Trends

Opponents have a miss rate of just 23% against Diamondbacks pitchers this season — 3rd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

Diamondbacks pitchers have a strikeout rate of just 39% with two-strikes this season — 3rd lowest in MLB.

Diamondbacks pitchers have struck out just 17% of left-handed batters they faced this season — lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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