• The Twins are -115 favorites vs the White Sox
• Twins vs White Sox Over / Under today: 7.5 Runs
• Twins / White Sox TV Channel: TWTV | CHSN

The Minnesota Twins (-115) visit Rate Field to take on the Chicago White Sox (-105) on May 26, 2026. First pitch is scheduled for 7:40 pm in Chicago, IL.

This season, the Twins are against the spread (ATS), while the White Sox are ATS.

Twins vs White Sox Starting Pitchers Today:

• Twins starting pitcher: Joe Ryan 3-3, 3.02 ERA
• White Sox starting pitcher: Sean Burke 2-3, 4.05 ERA

Twins vs. White Sox Odds, Run Line, Over/Under & Moneyline

Twins vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the White Sox will win Tuesday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Twins vs White Sox and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Twins players for Tuesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

• Victor Caratini has hit the Runs Under in 18 of his last 20 games (+14.05 Units / 32% ROI)
• Victor Caratini has hit the Hits Runs and RBIs Under in 17 of his last 20 games (+13.25 Units / 47% ROI)
• Victor Caratini has hit the Hits Under in 14 of his last 20 games (+13.00 Units / 65% ROI)
• Josh Bell has hit the Walks Under in 17 of his last 20 games (+11.35 Units / 27% ROI)
• Brooks Lee has hit the Total Bases Over in 15 of his last 20 away games (+10.60 Units / 38% ROI)

And here are some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

• Drew Romo has hit the Home Runs Over in 3 of his last 8 games at home (+22.50 Units / 281% ROI)
• Chase Meidroth has hit the Runs Over in 15 of his last 25 games (+13.20 Units / 53% ROI)
• Chase Meidroth has hit the Total Bases Over in 18 of his last 25 games (+10.70 Units / 29% ROI)
• Chase Meidroth has hit the Hits Runs and RBIs Over in 17 of his last 25 games (+10.25 Units / 39% ROI)
• Miguel Vargas has hit the Hits Over in 13 of his last 15 games at home (+9.05 Units / 31% ROI)

Twins Best Bets Today:

• The Minnesota Twins have hit the Team Total Over in 32 of their last 50 games (+11.75 Units / 20% ROI)
• The Minnesota Twins have covered the Run Line in 12 of their last 14 games (+10.00 Units / 48% ROI)
• The Minnesota Twins have hit the Game Total Over in 24 of their last 40 games (+9.55 Units / 22% ROI)
• The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Over in 16 of their last 23 games (+8.95 Units / 33% ROI)
• The Minnesota Twins have hit the Moneyline in 10 of their last 14 games (+6.90 Units / 45% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the Team Total Over in 23 of their last 35 games (+9.60 Units / 24% ROI)
• The Chicago White Sox have hit the Game Total Over in 30 of their last 50 games (+9.30 Units / 17% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 15 games (+9.00 Units / 49% ROI)
• The Chicago White Sox have covered the Run Line in 17 of their last 24 games (+8.90 Units / 24% ROI)
• The Chicago White Sox have hit the Moneyline in 10 of their last 12 games at home (+8.65 Units / 69% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

White Sox vs Twins Home Run Prop Bets Today

White Sox vs Twins Total Hits Prop Bets Today

White Sox vs Twins Strikeout Prop Bets Today

Twins Keys to the Game vs. the White Sox

The Twins are just 0-21 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .103.

The Twins are just 0-24 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .054.

The Twins are just 2-5 (.286) when tied entering the 7th inning this season — tied for 4th lowest in MLB; League Avg: .500.

The Twins are just 10-13 (.435) vs the bottom 10 runs allowed teams this season Today, they face the White Sox (24th runs allowed).

White Sox Keys to the Game vs. the Twins

The White Sox are just 25-109 (.187) when scoring 4 or fewer runs since the 2025 season — 2nd lowest in MLB; League Avg: .285.

The White Sox are just 98-41 (.705) when leading entering the 7th inning since the 2024 season — lowest in MLB; League Avg: .865.

The White Sox are just 65-18 (.783) when leading entering the 7th inning since the 2025 season — 2nd lowest in MLB; League Avg: .872.

The White Sox are just 13-110 (.106) when allowing 10 or more hits since the 2024 season — lowest in MLB; League Avg: .252.

Twins Hitting Stats & Trends

The Twins are batting just .205 with two outs this season — tied for 2nd lowest in MLB.

The Twins are batting just .285 on the first pitch of at-bats this season — 3rd lowest in MLB.

Twins hitters have a Hard-Hit Rate of just 35% on pitches 95 mph or greater this season — lowest in MLB.

Twins hitters have an OBP of .341 (675 PA’s) against LHP this season — tied for 3rd best in MLB.

White Sox Hitting Stats & Trends

White Sox hitters are slugging .705 on the first pitch of at-bats this season — 2nd best in MLB.

White Sox hitters are slugging .445 against LHP this season — 3rd best in MLB.

White Sox hitters have an OPS of .780 (546 PA’s) against LHP this season — 3rd best in MLB.

The White Sox are batting just .128 on pitches out of the zone this season — 4th lowest in MLB.

Twins Pitching Stats & Trends

Opponents have a groundball rate of just 40% against Twins pitchers this season — 3rd lowest in MLB.

Opponents have a miss rate of just 23% against Twins pitchers this season — tied for 4th lowest in MLB.

Twins pitchers have a strikeout rate of just 18% in late innings this season — lowest in MLB.

Twins pitchers have an ERA of 4.94 (213.0 IP) on the road this season — 5th highest in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 13% of batters when facing the leadoff batter in the inning this season — tied for highest in MLB.

Opponents have a miss rate of just 23% against White Sox pitchers this season — tied for 4th lowest in MLB.

White Sox pitchers have a strikeout rate of just 39% with two-strikes this season — 4th lowest in MLB.

White Sox pitchers have walked 10% of batters this season — 5th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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