• The Astros are -165 favorites vs the White Sox
• White Sox vs Astros Over / Under today: 8.5 Runs
• White Sox / Astros TV Channel: CHSN | SCHN

The Chicago White Sox (+135) visit Daikin Park to take on the Houston Astros (-165) on September 3, 2026. First pitch is scheduled for 2:10 pm in Houston, TX.

This season, the White Sox are against the spread (ATS), while the Astros are ATS.

White Sox vs Astros Starting Pitchers Today:

• White Sox starting pitcher: Luis Castillo 4-10, 5.33 ERA
• Astros starting pitcher: Hunter Brown 4-3, 3.34 ERA

White Sox vs. Astros Odds, Run Line, Over/Under & Moneyline

White Sox vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Thursday‘s MLB game with 55.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Thursday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Tristan Peters has hit the Home Runs Over in 4 of his last 10 games (+30.50 Units / 305% ROI)
• Miguel Vargas has hit the Walks Over in 18 of his last 25 games (+18.05 Units / 72% ROI)
• Sam Antonacci has hit the Hits Under in 16 of his last 25 away games (+17.75 Units / 71% ROI)
• Munetaka Murakami has hit the Singles Under in 21 of his last 25 games (+12.70 Units / 25% ROI)
• Sam Antonacci has hit the Total Bases Under in 17 of his last 20 away games (+11.50 Units / 33% ROI)

And here are some favorite MLB player prop bets for Astros players for Thursday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Jeremy Pena has hit the Hits Under in 18 of his last 25 games (+13.30 Units / 30% ROI)
• Cam Smith has hit the Singles Under in 14 of his last 15 games (+12.45 Units / 56% ROI)
• Daulton Varsho has hit the Hits Runs and RBIs Under in 19 of his last 25 games at home (+11.30 Units / 35% ROI)
• Isaac Paredes has hit the Walks Over in 11 of his last 15 games (+10.55 Units / 70% ROI)
• Jeremy Pena has hit the Home Runs Over in 3 of his last 9 games (+10.50 Units / 117% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 24 of their last 35 away games (+10.70 Units / 25% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 28 of their last 45 away games (+9.05 Units / 16% ROI)
• The Chicago White Sox have covered the Run Line in 27 of their last 45 games (+7.35 Units / 12% ROI)
• The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 14 of their last 30 away games (+5.75 Units / 18% ROI)
• The Chicago White Sox have hit the Moneyline in 14 of their last 25 away games (+4.80 Units / 19% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 23 games (+9.50 Units / 33% ROI)
• The Houston Astros have covered the Run Line in 22 of their last 40 games (+7.05 Units / 14% ROI)
• The Houston Astros have hit the Team Total Under in 8 of their last 10 games at home (+6.05 Units / 54% ROI)
• The Houston Astros have hit the Game Total Under in 7 of their last 10 games at home (+3.70 Units / 34% ROI)
• The Houston Astros have hit the Moneyline in 6 of their last 9 games (+3.65 Units / 37% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

White Sox Keys to the Game vs. the Astros

The White Sox are 23-25 (.479) when their opponents score in the first inning this season — 3rd best in MLB.

The White Sox are 14-5 (.737) when tied entering the 7th inning this season — 2nd best in MLB.

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

Astros Keys to the Game vs. the White Sox

The Astros are 12-5 (.706) when tied entering the 8th inning this season — 2nd best in MLB.

The Astros are 52-3 (.945) when leading entering the 7th inning this season — 2nd best in MLB.

The Astros are 61-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Astros are 85-59 (.590) after a loss since the 2025 season — 3rd best in MLB.

White Sox Hitting Stats & Trends

White Sox hitters have 126 extra-base hits out of 320 total hits (39%) against LHP this season — best in MLB.

White Sox hitters have 66 extra-base hits out of 135 total hits (49%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

The White Sox are 43-19 (.694) against the run line (24.7% ROI) vs bottom 10 scoring offenses this season Today, they face the Astros (10th in runs scored).

White Sox hitters have grounded into 63 double plays in 1,001 opportunities (6%) this season — best in MLB.

Astros Hitting Stats & Trends

29% of Astros hitters strikeouts have come on 95+ MPH fastballs this season — 2nd highest in MLB.

The Astros have scored first in just 39% of their games against division opponents this season — 2nd lowest in MLB.

Astros hitters have 42 extra-base hits out of 155 total hits (just 27%) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Astros hitters have drawn walks in 13% of their PA’s with runners in scoring position this season — best in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 10% of batters when facing the leadoff batter in the inning this season — 4th highest in MLB.

The White Sox have won 50% of home games in which their opponents scored first this season — 2nd highest in MLB.

Opponents have a groundball rate of just 40% against White Sox pitchers this season — tied for 4th lowest in MLB.

White Sox pitchers have an ERA of 3.24 (347.1 IP) against division opponents this season — 3rd best in MLB.

Astros Pitching Stats & Trends

Opponents have a groundball rate of just 39% against Astros pitchers this season — 2nd lowest in MLB.

Astros pitchers have walked 11% of batters this season — highest in MLB.

Astros pitchers have walked 11% of batters when facing the leadoff batter in the inning this season — highest in MLB.

The Astros have allowed 3.12 runs per game (437/140) in the first 5 innings this season — 3rd highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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