• The Guardians are -145 favorites vs the White Sox
• White Sox vs Guardians Over / Under today: 8.5 Runs
• White Sox / Guardians TV Channel: PEAC | NBCX

The Chicago White Sox (+118) visit Progressive Field to take on the Cleveland Guardians (-145) on July 5, 2026. First pitch is scheduled for 2:00 pm in Cleveland, OH.

This season, the White Sox are 46-42 against the spread (ATS), while the Guardians are 42-47 ATS.

White Sox vs Guardians Starting Pitchers Today:

• White Sox starting pitcher: Chris Murphy 2-0, 3.79 ERA
• Guardians starting pitcher: Tanner Bibee 2-9, 3.72 ERA

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Sunday‘s MLB game with 57.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on White Sox vs Guardians and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

• Sam Antonacci has hit the Home Runs Over in 3 of his last 8 away games (+21.10 Units / 264% ROI)
• Tristan Peters has hit the Hits Runs and RBIs Over in 19 of his last 25 away games (+13.70 Units / 44% ROI)
• Braden Montgomery has hit the Total Bases Over in 11 of his last 15 games (+8.80 Units / 48% ROI)
• Tristan Peters has hit the Hits Over in 18 of his last 25 away games (+8.80 Units / 24% ROI)
• Colson Montgomery has hit the Singles Under in 19 of his last 25 away games (+8.80 Units / 19% ROI)

And here are some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Chase DeLauter has hit the Walks Under in 21 of his last 25 games (+12.70 Units / 25% ROI)
• Daniel Schneemann has hit the Total Bases Under in 15 of his last 20 games (+10.65 Units / 49% ROI)
• Daniel Schneemann has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+9.90 Units / 37% ROI)
• Daniel Schneemann has hit the Hits Under in 12 of his last 15 games (+9.70 Units / 63% ROI)
• Daniel Schneemann has hit the Singles Under in 13 of his last 15 games (+9.10 Units / 34% ROI)

White Sox Best Bets Today:

• The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 32 of their last 50 games (+12.45 Units / 21% ROI)
• The Chicago White Sox have hit the Moneyline in 29 of their last 50 games (+10.80 Units / 20% ROI)
• The Chicago White Sox have hit the Team Total Over in 30 of their last 50 away games (+8.65 Units / 15% ROI)
• The Chicago White Sox have hit the Game Total Over in 29 of their last 50 games (+8.20 Units / 15% ROI)
• The Chicago White Sox have covered the Run Line in 31 of their last 50 games (+8.05 Units / 11% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have hit the Team Total Under in 25 of their last 40 games (+8.35 Units / 18% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 13 games (+7.40 Units / 47% ROI)
• The Cleveland Guardians have hit the Game Total Under in 23 of their last 40 games (+3.95 Units / 9% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 8 of their last 18 games at home (+3.40 Units / 15% ROI)
• The Cleveland Guardians have hit the Moneyline in 7 of their last 11 games at home (+2.45 Units / 18% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 50-36 against the Run Line (+2.05 Units / 1.61% ROI).

• 46-42 when betting on the Moneyline for +10.85 Units / 11.68% ROI
• 50-36 when betting on the total runs Over for +10.65 Units / 11.08% ROI
• 36-50 when betting on the total runs Under for -19.45 Units / -19.96% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 42-47 against the Run Line (-7.9 Units / -6.8% ROI).

• 47-43 when betting on the Moneyline for +2.75 Units / 2.58% ROI
• 43-47 when betting on the total runs Over for -8.2 Units / -8.34% ROI
• 47-43 when betting on the total runs Under for -0.75 Units / -0.75% ROI

Guardians vs White Sox Home Run Prop Bets Today

Guardians vs White Sox Total Hits Prop Bets Today

Guardians vs White Sox Strikeout Prop Bets Today

White Sox Keys to the Game vs. the Guardians

The White Sox are 9-3 (.750) when tied entering the 7th inning this season — 3rd best in MLB; League Avg: .500.

The White Sox are just 30-7 (.811) when leading entering the 7th inning this season — 5th lowest in MLB; League Avg: .861.

The White Sox are just 3-20 (.130) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .247.

The White Sox are 7-32 (.179) when trailing entering the 7th inning this season — 5th best in MLB; League Avg: .139.

Guardians Keys to the Game vs. the White Sox

The Guardians are 15-2 (.882) when they’ve hit 2 or more home runs this season — 2nd best in MLB; League Avg: .705.

The Guardians are 25-17 (.595) after a loss this season — 4th best in MLB; League Avg: .485.

The Guardians are 99-8 (.925) when leading entering the 7th inning since the 2025 season — 2nd best in MLB; League Avg: .870.

The Guardians are 33-3 (.917) when they’ve had 5 or more XBH since the 2025 season — best in MLB; League Avg: .795.

White Sox Hitting Stats & Trends

White Sox hitters have 47 extra-base hits out of 95 total hits (49%) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

The White Sox have a winning percentage of 67% at home this season — 3rd best in MLB.

White Sox hitters are slugging .431 against LHP this season — 4th best in MLB.

White Sox hitters have struck out in 25% of their PA’s against LHP this season — 5th highest in MLB.

Guardians Hitting Stats & Trends

The Guardians are batting just .199 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Guardians hitters have an OBP of just .272 (385 PA’s) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB.

Guardians hitters have an OBP of just .238 (232 PA’s) against pitchers who have thrown at least 80 pitches in a game this season — lowest in MLB.

The Guardians are batting just .218 on the road this season — lowest in MLB.

White Sox Pitching Stats & Trends

White Sox pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — tied for highest in MLB.

White Sox pitchers have won only 20% of games in which they have allowed their opponent to score in three different innings this season — 5th lowest in MLB.

The White Sox have won 56% of home games in which their opponents scored first this season — 2nd highest in MLB.

White Sox pitchers have walked 10% of batters this season — 4th highest in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 30% in close and late situations this season — best in MLB.

Opponents have a miss rate of 27% against Guardians pitchers this season — 4th best in MLB.

Guardians pitchers have a strikeout rate of 24% this season — 4th best in MLB.

Guardians pitchers have won 35% of games in which they have allowed their opponent to score in three different innings this season — 5th highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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