• The Yankees are -145 favorites vs the Astros
• Yankees vs Astros Over / Under today: 9 Runs
• Yankees / Astros TV Channel: SCHN | YES

The New York Yankees (-145) visit Daikin Park to take on the Houston Astros (+120) on April 24, 2026. First pitch is scheduled for 8:10 pm in Houston, TX.

This season, the Yankees are 16-9 against the spread (ATS), while the Astros are 10-16 ATS.

Yankees vs Astros Starting Pitchers Today:

• Yankees starting pitcher: Will Warren 2-0, 2.49 ERA
• Astros starting pitcher: Lance McCullers 1-1, 6.20 ERA

Yankees vs. Astros Odds, Run Line, Over/Under & Moneyline

Yankees vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Yankees will win Friday‘s MLB game with 57.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Yankees vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Yankees players for Friday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Bets Today:

• Ben Rice has hit the Home Runs Over in 4 of his last 6 games (+12.35 Units / 206% ROI)
• Ben Rice has hit the Hits Over in 16 of his last 20 games (+8.05 Units / 22% ROI)
• Ben Rice has hit the Runs Over in 13 of his last 20 games (+7.95 Units / 37% ROI)
• Aaron Judge has hit the Total Bases Under in 8 of his last 9 away games (+6.70 Units / 57% ROI)
• Austin Wells has hit the Hits Runs and RBIs Under in 13 of his last 20 games (+6.55 Units / 25% ROI)

And here are some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Yordan Alvarez has hit the Home Runs Over in 6 of his last 9 games at home (+17.25 Units / 192% ROI)
• Yordan Alvarez has hit the Runs Over in 17 of his last 20 games at home (+13.80 Units / 55% ROI)
• Yordan Alvarez has hit the Hits Runs and RBIs Over in 13 of his last 15 games at home (+11.15 Units / 63% ROI)
• Yordan Alvarez has hit the RBIs Over in 8 of his last 9 games (+9.80 Units / 109% ROI)
• Yordan Alvarez has hit the Hits Over in 13 of his last 20 games at home (+8.75 Units / 27% ROI)

Yankees Best Bets Today:

• The New York Yankees have covered the Run Line in 23 of their last 35 away games (+14.35 Units / 37% ROI)
• The New York Yankees have hit the Team Total Over in 24 of their last 35 away games (+12.05 Units / 30% ROI)
• The New York Yankees have hit the Game Total Under in 27 of their last 45 games (+9.25 Units / 19% ROI)
• The New York Yankees have hit the Moneyline in 24 of their last 35 away games (+8.85 Units / 18% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 23 of their last 40 away games (+8.70 Units / 15% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 30 games (+11.70 Units / 34% ROI)
• The Houston Astros have hit the Game Total Over in 18 of their last 24 games (+11.10 Units / 41% ROI)
• The Houston Astros have hit the Team Total Over in 14 of their last 21 games at home (+6.35 Units / 26% ROI)
• The Houston Astros have covered the Run Line in 6 of their last 11 games at home (+2.40 Units / 20% ROI)
• The Houston Astros have hit the Moneyline in 7 of their last 11 games at home (+1.65 Units / 10% ROI)

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 14-11 against the Run Line (+5.55 Units / 20.37% ROI).

• 16-9 when betting on the Moneyline for -0.85 Units / -2.05% ROI
• 9-14 when betting on the total runs Over for -6.35 Units / -23.26% ROI
• 14-9 when betting on the total runs Under for +3.95 Units / 14.26% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 10-16 against the Run Line (-6.35 Units / -20.29% ROI).

• 10-16 when betting on the Moneyline for -10.25 Units / -29.88% ROI
• 18-8 when betting on the total runs Over for +8.8 Units / 29.98% ROI
• 8-18 when betting on the total runs Under for -11.5 Units / -41.22% ROI

Astros vs Yankees Home Run Prop Bets Today

Astros vs Yankees Total Hits Prop Bets Today

Astros vs Yankees Strikeout Prop Bets Today

Yankees Keys to the Game vs. the Astros

The Yankees are 2-6 (.250) when trailing entering the 9th inning this season — best in MLB; League Avg: .050.

The Yankees are 52-41 (.559) on the road since the 2025 season — best in MLB; League Avg: .457.

The Yankees are 2-6 (.250) when trailing entering the 8th inning this season — tied for 2nd best in MLB; League Avg: .104.

The Yankees are 10-1 (.909) when scoring 5 or more runs this season — 5th best in MLB; League Avg: .764.

Astros Keys to the Game vs. the Yankees

The Astros are just 0-14 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .104.

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros are just 0-13 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Astros were 71-4 (.947) when leading entering the 8th inning in the 2025 season — tied for 2nd best in MLB; League Avg: .909.

Yankees Hitting Stats & Trends

Yankees hitters slugged .458 on the road in the 2025 season — best in MLB.

Yankees hitters drew walks in 11% of their PA’s against LHP in the 2025 season — best in MLB.

Yankees hitters slugged .457 against LHP in the 2025 season — best in MLB.

Yankees hitters have drawn walks in 11% of their PA’s against LHP since the 2024 season — best in MLB.

Astros Hitting Stats & Trends

Astros hitters have an OPS of .904 (169 PA’s) in lefty-lefty matchups since the 2025 season — best in MLB.

The Astros are batting .326 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OPS of 1.123 (60 PA’s) in lefty-lefty matchups this season — 2nd best in MLB.

The Astros batted .253 with two outs in the 2025 season — 2nd best in MLB.

Yankees Pitching Stats & Trends

The Yankees have allowed 2.00 runs per game (24/12) on the road this season — best in MLB.

The Yankees pitchers have allowed their opponents to score first in just 33% of their games on the road since the 2024 season — lowest in MLB.

Yankees pitchers have allowed an OBP of just .250 (224 PA’s) when facing the leadoff batter in the inning this season — best in MLB.

Yankees pitchers have an ERA of 1.79 (105.2 IP) on the road this season — best in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 14% of batters this season — highest in MLB.

The Astros have allowed 3.88 runs per game (101/26) in the first 5 innings this season — highest in MLB.

Astros pitchers have a strikeout rate of 46% with two-strikes since the 2025 season — tied for best in MLB.

Astros pitchers have an ERA of 6.16 (172.1 IP) this month (20 games) — highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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