• The Yankees are -150 favorites vs the Astros
• Yankees vs Astros Over / Under today: 9 Runs
• Yankees / Astros TV Channel: SCHN | YES

The New York Yankees (-150) visit Daikin Park to take on the Houston Astros (+125) on April 25, 2026. First pitch is scheduled for 7:10 pm in Houston, TX.

This season, the Yankees are against the spread (ATS), while the Astros are ATS.

Yankees vs Astros Starting Pitchers Today:

• Yankees starting pitcher: Ryan Weathers 1-2, 3.22 ERA
• Astros starting pitcher: Michael Burrows 1-3, 6.76 ERA

Yankees vs. Astros Odds, Run Line, Over/Under & Moneyline

Yankees vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Yankees will win Saturday‘s MLB game with 59.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Yankees vs Astros and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Yankees players for Saturday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Bets Today:

• Ben Rice has hit the Home Runs Over in 5 of his last 7 games (+15.85 Units / 226% ROI)
• Cody Bellinger has hit the Total Bases Under in 19 of his last 25 away games (+10.45 Units / 26% ROI)
• Giancarlo Stanton has hit the Walks Under in his last 9 games (+9.00 Units / 61% ROI)
• Jose Caballero has hit the Singles Over in 7 of his last 8 games (+8.50 Units / 106% ROI)
• Ben Rice has hit the Hits Over in 16 of his last 20 games (+8.05 Units / 22% ROI)

And here are some favorite MLB player prop bets for Astros players for Saturday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

• Yordan Alvarez has hit the Home Runs Over in 6 of his last 10 games at home (+16.25 Units / 162% ROI)
• Yordan Alvarez has hit the Hits Over in 14 of his last 20 games at home (+11.65 Units / 36% ROI)
• Yordan Alvarez has hit the Runs Over in 16 of his last 20 games at home (+11.50 Units / 46% ROI)
• Yordan Alvarez has hit the RBIs Over in 13 of his last 20 games (+10.30 Units / 51% ROI)
• Yordan Alvarez has hit the Total Bases Over in 15 of his last 20 games at home (+10.05 Units / 47% ROI)

Yankees Best Bets Today:

• The New York Yankees have covered the Run Line in 23 of their last 35 away games (+14.10 Units / 37% ROI)
• The New York Yankees have hit the Team Total Over in 24 of their last 35 away games (+12.05 Units / 30% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 24 of their last 40 away games (+10.85 Units / 19% ROI)
• The New York Yankees have hit the Moneyline in 27 of their last 40 away games (+9.50 Units / 17% ROI)
• The New York Yankees have covered the 1st Five Innings (F5) Run Line in 25 of their last 40 away games (+8.20 Units / 18% ROI)

Astros Best Bets Today:

• The Houston Astros have hit the Game Total Over in 19 of their last 25 games (+12.10 Units / 43% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 21 of their last 30 games (+11.65 Units / 33% ROI)
• The Houston Astros have hit the Team Total Over in 15 of their last 22 games at home (+7.35 Units / 28% ROI)
• The Houston Astros have covered the Run Line in 6 of their last 12 games at home (+1.20 Units / 9% ROI)
• The Houston Astros have hit the 1st Five Innings (F5) Moneyline in 3 of their last 5 games (+1.15 Units / 21% ROI)

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are against the Run Line ( Units / ROI).

• away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• away total over record when betting on the total runs Over for over units Units / over ROI ROI
• away total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are against the Run Line ( Units / ROI).

• home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
• home total over record when betting on the total runs Over for over units Units / over ROI ROI
• home total under record when betting on the total runs Under for under units Units / under ROI ROI

Yankees Keys to the Game vs. the Astros

The Yankees are 2-6 (.250) when trailing entering the 9th inning this season — tied for best in MLB; League Avg: .051.

The Yankees are 2-6 (.250) when trailing entering the 8th inning this season — tied for 3rd best in MLB; League Avg: .103.

The Yankees are 3-6 (.333) when trailing entering the 7th inning this season — tied for 3rd best in MLB; League Avg: .135.

The Yankees are just 6-7 (.462) vs the bottom 10 runs allowed teams this season Today, they face the Astros (29th runs allowed).

Astros Keys to the Game vs. the Yankees

The Astros are 30-22 (.577) vs top 10 scoring offenses since the 2025 season Today, they face the Yankees (ninth in runs scored).

The Astros are just 0-15 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .103.

The Astros are just 2-10 (.167) when scoring 4 or fewer runs this season — tied for 2nd lowest in MLB; League Avg: .275.

The Astros are just 0-14 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .051.

Yankees Hitting Stats & Trends

Yankees hitters have an OPS of .783 (3,741 PA’s) on the road since the 2025 season — best in MLB.

Yankees hitters have an OPS of .782 (7,220 PA’s) since the 2025 season — best in MLB.

Yankees hitters are slugging .686 on the first pitch of at-bats since the 2025 season — best in MLB.

Yankees hitters are slugging .452 against LHP since the 2025 season — best in MLB.

Astros Hitting Stats & Trends

Astros hitters have an OBP of .431 (116 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .358 (520 PA’s) on the road this season — 2nd best in MLB.

Astros hitters have put 45% of balls in play to the left side of the field with runners in scoring position since the 2025 season — highest in MLB.

The Astros are batting .337 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Yankees Pitching Stats & Trends

Yankees pitchers have an ERA of 1.67 (54.0 IP) over the past seven days (6 games) — best in MLB.

Yankees pitchers have allowed an OBP of just .253 (233 PA’s) when facing the leadoff batter in the inning this season — best in MLB.

The Yankees have allowed 1.83 runs per game (11/6) over the past seven days (6 games) — best in MLB.

Yankees pitchers have a strikeout rate of 27% with runners in scoring position this season — best in MLB.

Astros Pitching Stats & Trends

Astros pitchers have walked 14% of batters this season — highest in MLB.

Astros pitchers have an ERA of 5.97 (235.1 IP) this season — highest in MLB.

The Astros have allowed 3.93 runs per game (106/27) in the first 5 innings this season — highest in MLB.

Astros pitchers have an ERA of 6.35 (181.1 IP) this month (21 games) — highest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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