• The Yankees are -145 favorites vs the Diamondbacks
• Yankees vs Diamondbacks Over / Under today: 7.5 Runs
• Yankees / Diamondbacks TV Channel: DBTV | YES

The New York Yankees (-145) visit Chase Field to take on the Arizona Diamondbacks (+120) on September 19, 2026. First pitch is scheduled for 8:10 pm in Phoenix, AZ.

This season, the Yankees are 89-64 against the spread (ATS), while the Diamondbacks are 78-71 ATS.

Yankees vs Diamondbacks Starting Pitchers Today:

• Yankees starting pitcher: Cam Schlittler 14-6, 1.95 ERA
• Diamondbacks starting pitcher: Brandon Pfaadt 7-3, 3.78 ERA

Yankees vs. Diamondbacks Odds, Run Line, Over/Under & Moneyline

Yankees vs Diamondbacks Prediction for Today’s Game

Based on recent trends the model predicts the Yankees will win Saturday‘s MLB game with 58.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Yankees players for Saturday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Bets Today:

• Cam Schlittler has hit the Earned Runs Under in 20 of his last 25 games (+16.25 Units / 54% ROI)
• Ryan McMahon has hit the Runs Under in 18 of his last 20 games (+14.20 Units / 34% ROI)
• Aaron Judge has hit the Hits Under in 14 of his last 20 games (+13.90 Units / 56% ROI)
• Cody Bellinger has hit the Home Runs Over in 4 of his last 9 games (+13.80 Units / 153% ROI)
• Cody Bellinger has hit the Hits Runs and RBIs Over in 19 of his last 25 games (+12.55 Units / 43% ROI)

And here are some favorite MLB player prop bets for Diamondbacks players for Saturday‘s game, looking at profitable historical betting trends:

Best Diamondbacks Player Prop Best Bets Today:

• Gabriel Moreno has hit the Home Runs Over in 3 of his last 5 games (+22.00 Units / 440% ROI)
• Lars Nootbaar has hit the Runs Under in 21 of his last 25 games (+15.85 Units / 45% ROI)
• Gabriel Moreno has hit the Total Bases Over in 17 of his last 25 games (+13.20 Units / 53% ROI)
• Lars Nootbaar has hit the Hits Under in 11 of his last 15 games at home (+12.65 Units / 84% ROI)
• Gabriel Moreno has hit the RBIs Over in 14 of his last 25 games (+12.60 Units / 50% ROI)

Yankees Best Bets Today:

• The New York Yankees have covered the Run Line in 23 of their last 35 games (+16.85 Units / 42% ROI)
• The New York Yankees have hit the Game Total Over in 17 of their last 25 games (+9.45 Units / 35% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 16 of their last 30 away games (+9.45 Units / 23% ROI)
• The New York Yankees have hit the Moneyline in 21 of their last 30 games (+9.40 Units / 21% ROI)
• The New York Yankees have covered the 1st Five Innings (F5) Run Line in 15 of their last 22 away games (+8.05 Units / 32% ROI)

Diamondbacks Best Bets Today:

• The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 25 games (+14.65 Units / 46% ROI)
• The Arizona Diamondbacks have hit the Game Total Under in 16 of their last 24 games (+7.30 Units / 28% ROI)
• The Arizona Diamondbacks have hit the Team Total Under in 15 of their last 23 games (+5.05 Units / 18% ROI)

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 78-74 against the Run Line (+13.9 Units / 8.01% ROI).

• 89-64 when betting on the Moneyline for -1.3 Units / -0.57% ROI
• 69-79 when betting on the total runs Over for -18.3 Units / -10.84% ROI
• 79-69 when betting on the total runs Under for +3.35 Units / 1.99% ROI

Diamondbacks Against the Spread (ATS) Record

Against the spread this season, the Diamondbacks are 78-71 against the Run Line (-4.75 Units / -2.33% ROI).

• 80-74 when betting on the Moneyline for +4.65 Units / 2.57% ROI
• 65-83 when betting on the total runs Over for -26.35 Units / -15.5% ROI
• 83-65 when betting on the total runs Under for +12.05 Units / 7.13% ROI

Yankees Keys to the Game vs. the Diamondbacks

The Yankees are 53-6 (.898) when they’ve hit 2 or more home runs this season — best in MLB.

The Yankees are 38-4 (.905) when they’ve had 10 or more hits this season — best in MLB.

The Yankees are 58-6 (.906) when scoring 5 or more runs this season — best in MLB.

The Yankees are 22-2 (.917) when they’ve had 5 or more XBH this season — 5th best in MLB.

Diamondbacks Keys to the Game vs. the Yankees

The Diamondbacks are 67-0 (1.000) when leading entering the 9th inning this season — tied for best in MLB.

The Diamondbacks were just 67-7 (.905) when leading entering the 9th inning in the 2025 season — 2nd lowest in MLB; League Avg: .956.

The Diamondbacks were just 61-17 (.782) when leading entering the 7th inning in the 2025 season — 2nd lowest in MLB; League Avg: .875.

The Diamondbacks were 5-59 (.077) when trailing entering the 9th inning in the 2024 season — 4th best in MLB; League Avg: .050.

Yankees Hitting Stats & Trends

The Yankees are batting just .126 on pitches out of the zone this season — lowest in MLB.

Yankees hitters are slugging just .177 on pitches out of the zone this season — lowest in MLB.

The Yankees are batting just .154 with two-strikes this season — 2nd lowest in MLB.

Yankees hitters have an OPS of .776 (1,835 PA’s) in innings 7-9 this season — best in MLB.

Diamondbacks Hitting Stats & Trends

The Diamondbacks are batting .274 against LHP this season — best in MLB.

Diamondbacks hitters have struck out in just 18% of their PA’s against LHP this season — 2nd best in MLB.

Diamondbacks hitters have a swing rate of just 25% on the first pitch of at-bats this season — lowest in MLB.

Diamondbacks hitters have an OPS of .778 (1,619 PA’s) against LHP this season — 2nd best in MLB.

Yankees Pitching Stats & Trends

Yankees pitchers have an ERA of 2.87 (700.0 IP) on the road this season — best in MLB.

Opponents have a groundball rate of 45% against Yankees pitchers this season — 5th highest in MLB.

Yankees pitchers have allowed innings of 3+ runs in 4% of innings played this season — lowest in MLB.

The Yankees have allowed 3.37 runs per game (266/79) on the road this season — best in MLB.

Diamondbacks Pitching Stats & Trends

Opponents have a miss rate of just 23% against Diamondbacks pitchers this season — 2nd lowest in MLB.

The Diamondbacks pitchers have allowed division opponents to score first in just 37% of their games this season — 2nd lowest in MLB.

Diamondbacks pitchers have walked 8% of batters this season — 5th best in MLB.

Diamondbacks pitchers have a strikeout rate of just 19% this season — 2nd lowest in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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