• The Yankees are +100 favorites vs the Guardians
• Yankees vs Guardians Over / Under today: 8 Runs
• Yankees / Guardians TV Channel: GDTV | YES

The New York Yankees (+100) visit Progressive Field to take on the Cleveland Guardians (-120) on June 10, 2026. First pitch is scheduled for 1:10 pm in Cleveland, OH.

This season, the Yankees are 40-26 against the spread (ATS), while the Guardians are 34-35 ATS.

Yankees vs Guardians Starting Pitchers Today:

• Yankees starting pitcher: Carlos Rodon 1-2, 2.88 ERA
• Guardians starting pitcher: Parker Messick 6-2, 2.43 ERA

Yankees vs. Guardians Odds, Run Line, Over/Under & Moneyline

Yankees vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 51.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

Bet now on Yankees vs Guardians and all games with BetMGM

We’ve highlighted some favorite MLB player prop bets for Yankees players for Wednesday‘s game, looking at profitable historical betting trends:

Best Yankees Player Prop Bets Today:

• Anthony Volpe has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+10.20 Units / 38% ROI)
• Anthony Volpe has hit the Hits Under in 13 of his last 20 games (+7.80 Units / 38% ROI)
• Anthony Volpe has hit the Total Bases Under in 14 of his last 20 games (+6.05 Units / 24% ROI)
• Ben Rice has hit the RBIs Over in 6 of his last 9 away games (+5.45 Units / 61% ROI)
• Anthony Volpe has hit the Runs Over in 5 of his last 7 away games (+5.20 Units / 74% ROI)

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

• Angel Martinez has hit the Home Runs Over in 3 of his last 9 games at home (+12.60 Units / 140% ROI)
• Steven Kwan has hit the Total Bases Under in 20 of his last 25 games at home (+12.15 Units / 27% ROI)
• Travis Bazzana has hit the Singles Under in 15 of his last 20 games (+9.25 Units / 38% ROI)
• Steven Kwan has hit the Hits Runs and RBIs Under in 15 of his last 20 games at home (+9.00 Units / 38% ROI)
• Steven Kwan has hit the Hits Under in 14 of his last 25 games (+8.85 Units / 35% ROI)

Yankees Best Bets Today:

• The New York Yankees have hit the 1st Five Innings (F5) Team Total Under in 25 of their last 40 away games (+8.95 Units / 19% ROI)
• The New York Yankees have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 away games (+7.80 Units / 13% ROI)
• The New York Yankees have hit the 1st Five Innings (F5) Moneyline in 29 of their last 50 away games (+6.95 Units / 10% ROI)
• The New York Yankees have hit the Game Total Under in 23 of their last 40 away games (+6.45 Units / 15% ROI)
• The New York Yankees have covered the Run Line in 26 of their last 50 away games (+6.20 Units / 11% ROI)

Guardians Best Bets Today:

• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 30 of their last 50 games (+9.55 Units / 17% ROI)
• The Cleveland Guardians have hit the Team Total Under in 14 of their last 20 games (+7.50 Units / 33% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 30 of their last 50 games (+7.45 Units / 12% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 21 of their last 40 games (+6.90 Units / 14% ROI)
• The Cleveland Guardians have hit the Game Total Over in 8 of their last 11 games at home (+4.55 Units / 37% ROI)

Yankees Against the Spread (ATS) Record

Against the spread this season, the Yankees are 32-33 against the Run Line (+4.5 Units / 6.38% ROI).

• 40-26 when betting on the Moneyline for -0.85 Units / -0.82% ROI
• 29-33 when betting on the total runs Over for -7.6 Units / -10.46% ROI
• 33-29 when betting on the total runs Under for +0.9 Units / 1.24% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 34-35 against the Run Line (-1.65 Units / -1.88% ROI).

• 37-32 when betting on the Moneyline for +4.2 Units / 5.06% ROI
• 34-35 when betting on the total runs Over for -4.15 Units / -5.5% ROI
• 35-34 when betting on the total runs Under for -2.8 Units / -3.65% ROI

Guardians vs Yankees Home Run Prop Bets Today

Guardians vs Yankees Total Hits Prop Bets Today

Guardians vs Yankees Strikeout Prop Bets Today

Yankees Keys to the Game vs. the Guardians

The Yankees are 18-1 (.947) when they’ve had 10 or more hits this season — best in MLB; League Avg: .751.

The Yankees are 14-1 (.933) when they’ve had 5 or more XBH this season — 4th best in MLB; League Avg: .785.

The Yankees are 5-17 (.227) when trailing entering the 7th inning this season — 3rd best in MLB; League Avg: .143.

The Yankees are 13-10 (.565) vs the top 10 runs allowed teams this season Today, they face Guardians (ninth in runs allowed).

Guardians Keys to the Game vs. the Yankees

The Guardians are 19-12 (.613) after a loss this season — 3rd best in MLB; League Avg: .478.

The Guardians are just 1-23 (.042) when trailing entering the 7th inning this season — 5th lowest in MLB; League Avg: .143.

The Guardians are 11-2 (.846) when they’ve hit 2 or more home runs this season — 3rd best in MLB; League Avg: .708.

The Guardians are 32-3 (.914) when they’ve had 5 or more XBH since the 2025 season — 2nd best in MLB; League Avg: .795.

Yankees Hitting Stats & Trends

Yankees hitters have 130 extra-base hits out of 289 total hits (45%) against starting pitchers this season — best in MLB.

Yankees hitters are slugging .433 this season — 2nd best in MLB.

Yankees hitters are slugging .463 against LHP this season — best in MLB.

Yankees hitters have drawn walks in 15% of their PA’s when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Guardians Hitting Stats & Trends

The Guardians are hitting just .174 against pitchers who have thrown at least 80 pitches in the game this season — lowest in MLB.

Guardians hitters are slugging just .366 against RHP this season — 4th lowest in MLB.

Guardians hitters have an OPS of just .678 (1,820 PA’s) against RHP this season — 5th lowest in MLB.

Guardians hitters are slugging just .371 this season — 3rd lowest in MLB.

Yankees Pitching Stats & Trends

Opponents have a groundball rate of 47% against Yankees pitchers this season — highest in MLB.

Yankees pitchers have an ERA of 2.96 (307.1 IP) on the road this season — tied for best in MLB.

Yankees pitchers have an ERA of 3.25 (586.1 IP) this season — 3rd best in MLB.

Opponents are hitting just .223 against Yankees pitchers this season — 3rd best in MLB.

Guardians Pitching Stats & Trends

Guardians pitchers have a strikeout rate of 33% in close and late situations this season — best in MLB.

Opponents have a miss rate of 28% against Guardians pitchers this season — tied for 2nd best in MLB.

Guardians pitchers have a strikeout rate of 24% with runners in scoring position this season — 5th best in MLB.

Guardians pitchers have an ERA of 2.69 (127.0 IP) against division opponents this season — 2nd best in MLB.

More MLB Reading:

• Home Run Predictions Today
• Best NRFI Bets Today
• Strikeout Props Today
• MLB Starting Pitchers Today

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